| An integrated encyclopedia of DNA elements in the human genome ENCODE Project Consortium Nature 489 (7414), 57, 2012 | 13825 | 2012 |
| Comprehensive mapping of long-range interactions reveals folding principles of the human genome E Lieberman-Aiden, NL Van Berkum, L Williams, M Imakaev, T Ragoczy, ... science 326 (5950), 289-293, 2009 | 8470 | 2009 |
| Chromosomal Subunits in Active Genes Have an Altered Conformation: Globin genes are digested by deoxyribonuclease I in red blood cell nuclei but not in fibroblast nuclei. H Weintraub, M Groudine Science 193 (4256), 848-856, 1976 | 2161 | 1976 |
| A comparative encyclopedia of DNA elements in the mouse genome F Yue, Y Cheng, A Breschi, J Vierstra, W Wu, T Ryba, R Sandstrom, Z Ma, ... Nature 515 (7527), 355-364, 2014 | 1897 | 2014 |
| Controlling the double helix G Felsenfeld, M Groudine Nature 421 (6921), 448-453, 2003 | 1684 | 2003 |
| Cyclin E-CDK2 is a regulator of p27Kip1. RJ Sheaff, M Groudine, M Gordon, JM Roberts, BE Clurman Genes & development 11 (11), 1464-1478, 1997 | 1207 | 1997 |
| The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote D Schübeler, DM MacAlpine, D Scalzo, C Wirbelauer, C Kooperberg, ... Genes & development 18 (11), 1263-1271, 2004 | 1004 | 2004 |
| Functional and mechanistic diversity of distal transcription enhancers M Bulger, M Groudine Cell 144 (3), 327-339, 2011 | 978 | 2011 |
| A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells DL Bentley, M Groudine Nature 321 (6071), 702-706, 1986 | 968 | 1986 |
| An expansive human regulatory lexicon encoded in transcription factor footprints S Neph, J Vierstra, AB Stergachis, AP Reynolds, E Haugen, B Vernot, ... Nature 489 (7414), 83-90, 2012 | 946 | 2012 |
| Control of c-myc regulation in normal and neoplastic cells CA Spencer, M Groudine Advances in cancer research 56, 1-48, 1991 | 874 | 1991 |
| Transcriptional regulation of hemoglobin switching in chicken embryos M Groudine, M Peretz, H Weintraub Molecular and cellular biology 1 (3), 281-288, 1981 | 872 | 1981 |
| Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line S Collins, M Groudine Nature 298 (5875), 679-681, 1982 | 846 | 1982 |
| Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation. BE Clurman, RJ Sheaff, K Thress, M Groudine, JM Roberts Genes & development 10 (16), 1979-1990, 1996 | 654 | 1996 |
| Looping versus linking: toward a model for long-distance gene activation M Bulger, M Groudine Genes & development 13 (19), 2465-2477, 1999 | 626 | 1999 |
| Proximity among distant regulatory elements at the β-globin locus requires GATA-1 and FOG-1 CR Vakoc, DL Letting, N Gheldof, T Sawado, MA Bender, M Groudine, ... Molecular cell 17 (3), 453-462, 2005 | 625 | 2005 |
| A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus. WC Forrester, E Epner, MC Driscoll, T Enver, M Brice, ... Genes & development 4 (10), 1637-1649, 1990 | 601 | 1990 |
| Chromatin structure of endogenous retroviral genes and activation by an inhibitor of DNA methylation M Groudine, R Eisenman, H Weintraub Nature 292 (5821), 311-317, 1981 | 583 | 1981 |
| Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells MC Lorincz, DR Dickerson, M Schmitt, M Groudine Nature structural & molecular biology 11 (11), 1068-1075, 2004 | 572 | 2004 |
| Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids WC Forrester, S Takegawa, T Papayannopoulou, G Stamatoyannopoulos, ... Nucleic acids research 15 (24), 10159-10177, 1987 | 537 | 1987 |
