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Emma Guttman-Yassky
Emma Guttman-Yassky
Professor of Dermatology and Immunology, Mount Sinai Medical Center
Email verificata su mountsinai.org
Titolo
Citata da
Citata da
Anno
Two phase 3 trials of dupilumab versus placebo in atopic dermatitis
EL Simpson, T Bieber, E Guttman-Yassky, LA Beck, A Blauvelt, MJ Cork, ...
New England Journal of Medicine 375 (24), 2335-2348, 2016
17272016
Dupilumab treatment in adults with moderate-to-severe atopic dermatitis
LA Beck, D Thaçi, JD Hamilton, NM Graham, T Bieber, R Rocklin, JE Ming, ...
New England Journal of Medicine 371 (2), 130-139, 2014
14492014
Th17 cytokines interleukin (IL)‐17 and IL‐22 modulate distinct inflammatory and keratinocyte‐response pathways
KE Nograles, LC Zaba, E Guttman‐Yassky, J Fuentes‐Duculan, ...
British Journal of Dermatology 159 (5), 1092-1102, 2008
9612008
Progressive activation of TH2/TH22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis
JK Gittler, A Shemer, M Suárez-Fariñas, J Fuentes-Duculan, KJ Gulewicz, ...
Journal of Allergy and Clinical Immunology 130 (6), 1344-1354, 2012
9522012
IL-22–producing “T22” T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17–producing TH17 T cells
KE Nograles, LC Zaba, A Shemer, J Fuentes-Duculan, I Cardinale, ...
Journal of Allergy and Clinical Immunology 123 (6), 1244-1252. e2, 2009
7482009
Integrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis
A Chiricozzi, E Guttman-Yassky, M Suárez-Farinas, KE Nograles, S Tian, ...
Journal of Investigative Dermatology 131 (3), 677-687, 2011
6982011
The immunology of atopic dermatitis and its reversibility with broad-spectrum and targeted therapies
PM Brunner, E Guttman-Yassky, DYM Leung
Journal of Allergy and Clinical Immunology 139 (4), S65-S76, 2017
5952017
Anti–interleukin-31 receptor A antibody for atopic dermatitis
T Ruzicka, JM Hanifin, M Furue, G Pulka, I Mlynarczyk, A Wollenberg, ...
New England Journal of Medicine 376 (9), 826-835, 2017
5952017
Cellular and molecular immunologic mechanisms in patients with atopic dermatitis
T Werfel, JP Allam, T Biedermann, K Eyerich, S Gilles, E Guttman-Yassky, ...
Journal of allergy and clinical immunology 138 (2), 336-349, 2016
5882016
The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization
S Noda, M Suárez-Fariñas, B Ungar, SJ Kim, C de Guzman Strong, H Xu, ...
Journal of Allergy and Clinical Immunology 136 (5), 1254-1264, 2015
5542015
Deciphering the complexities of atopic dermatitis: shifting paradigms in treatment approaches
DYM Leung, E Guttman-Yassky
Journal of Allergy and Clinical Immunology 134 (4), 769-779, 2014
5182014
Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis
E Guttman-Yassky, R Bissonnette, B Ungar, M Suárez-Fariñas, ...
Journal of Allergy and Clinical Immunology 143 (1), 155-172, 2019
5162019
Intrinsic atopic dermatitis shows similar TH2 and higher TH17 immune activation compared with extrinsic atopic dermatitis
M Suárez-Fariñas, N Dhingra, J Gittler, A Shemer, I Cardinale, ...
Journal of Allergy and Clinical Immunology 132 (2), 361-370, 2013
4922013
Atopic dermatitis endotypes and implications for targeted therapeutics
T Czarnowicki, H He, JG Krueger, E Guttman-Yassky
Journal of Allergy and Clinical Immunology 143 (1), 1-11, 2019
4832019
Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis
JD Hamilton, M Suárez-Farinas, N Dhingra, I Cardinale, X Li, A Kostic, ...
Journal of Allergy and Clinical Immunology 134 (6), 1293-1300, 2014
4752014
Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities
M Suárez-Fariñas, SJ Tintle, A Shemer, A Chiricozzi, K Nograles, ...
Journal of Allergy and Clinical Immunology 127 (4), 954-964. e4, 2011
4652011
Tralokinumab for moderate‐to‐severe atopic dermatitis: results from two 52‐week, randomized, double‐blind, multicentre, placebo‐controlled phase III trials (ECZTRA 1 and ECZTRA 2)
A Wollenberg, A Blauvelt, E Guttman‐Yassky, M Worm, C Lynde, ...
British Journal of Dermatology 184 (3), 437-449, 2021
4062021
Contrasting pathogenesis of atopic dermatitis and psoriasis—part I: clinical and pathologic concepts
E Guttman-Yassky, KE Nograles, JG Krueger
Journal of Allergy and Clinical Immunology 127 (5), 1110-1118, 2011
4042011
Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis
E Guttman-Yassky, MA Lowes, J Fuentes-Duculan, LC Zaba, I Cardinale, ...
The Journal of Immunology 181 (10), 7420-7427, 2008
4022008
Efficacy and safety of dupilumab in adolescents with uncontrolled moderate to severe atopic dermatitis: a phase 3 randomized clinical trial
EL Simpson, AS Paller, EC Siegfried, M Boguniewicz, L Sher, ...
JAMA dermatology 156 (1), 44-56, 2020
4012020
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