| Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA AS Tan, JW Baty, LF Dong, A Bezawork-Geleta, B Endaya, J Goodwin, ... Cell metabolism 21 (1), 81-94, 2015 | 705 | 2015 |
| Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures YS Elhassan, K Kluckova, RS Fletcher, MS Schmidt, A Garten, CL Doig, ... Cell reports 28 (7), 1717-1728. e6, 2019 | 304 | 2019 |
| Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells LF Dong, J Kovarova, M Bajzikova, A Bezawork-Geleta, D Svec, ... elife 6, e22187, 2017 | 256 | 2017 |
| Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II LF Dong, VJA Jameson, D Tilly, J Cerny, E Mahdavian, ... Journal of Biological Chemistry 286 (5), 3717-3728, 2011 | 230 | 2011 |
| Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II LF Dong, VJA Jameson, D Tilly, J Cerny, E Mahdavian, ... Journal of Biological Chemistry 286 (5), 3717-3728, 2011 | 230 | 2011 |
| Reactivation of dihydroorotate dehydrogenase-driven pyrimidine biosynthesis restores tumor growth of respiration-deficient cancer cells M Bajzikova, J Kovarova, AR Coelho, S Boukalova, S Oh, K Rohlenova, ... Cell metabolism 29 (2), 399-416. e10, 2019 | 208 | 2019 |
| Mitochondrial complex II, a novel target for anti-cancer agents K Kluckova, A Bezawork-Geleta, J Rohlena, L Dong, J Neuzil Biochimica et Biophysica Acta (BBA)-Bioenergetics 1827 (5), 552-564, 2013 | 135 | 2013 |
| Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy LF Dong, VJA Jameson, D Tilly, L Prochazka, J Rohlena, K Valis, J Truksa, ... Free Radical Biology and Medicine 50 (11), 1546-1555, 2011 | 124 | 2011 |
| MicroRNA-126 suppresses mesothelioma malignancy by targeting IRS1 and interfering with the mitochondrial function M Tomasetti, L Nocchi, S Staffolani, N Manzella, M Amati, J Goodwin, ... Antioxidants & redox signaling 21 (15), 2109-2125, 2014 | 107 | 2014 |
| Oncogenic IDH1 mutations promote enhanced proline synthesis through PYCR1 to support the maintenance of mitochondrial redox homeostasis KER Hollinshead, H Munford, KL Eales, C Bardella, C Li, ... Cell reports 22 (12), 3107-3114, 2018 | 81 | 2018 |
| Sorafenib-induced apoptosis in hepatocellular carcinoma is reversed by SIRT1 A Garten, T Grohmann, K Kluckova, GG Lavery, W Kiess, M Penke International journal of molecular sciences 20 (16), 4048, 2019 | 74 | 2019 |
| Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation K Kluckova, M Sticha, J Cerny, T Mracek, L Dong, Z Drahota, E Gottlieb, ... Cell death & disease 6 (5), e1749-e1749, 2015 | 72 | 2015 |
| Mitochondrially targeted α-tocopheryl succinate is antiangiogenic: potential benefit against tumor angiogenesis but caution against wound healing J Rohlena, LF Dong, K Kluckova, R Zobalova, J Goodwin, D Tilly, J Stursa, ... Antioxidants & redox signaling 15 (12), 2923-2935, 2011 | 68 | 2011 |
| Metabolic implications of hypoxia and pseudohypoxia in pheochromocytoma and paraganglioma K Kluckova, DA Tennant Cell and tissue research 372, 367-378, 2018 | 54 | 2018 |
| Mitochondrially targeted vitamin E succinate modulates expression of mitochondrial DNA transcripts and mitochondrial biogenesis J Truksa, LF Dong, J Rohlena, J Stursa, M Vondrusova, J Goodwin, ... Antioxidants & redox signaling 22 (11), 883-900, 2015 | 50 | 2015 |
| Mitochondrial targeting overcomes ABCA1-dependent resistance of lung carcinoma to α-tocopheryl succinate L Prochazka, S Koudelka, LF Dong, J Stursa, J Goodwin, J Neca, J Slavik, ... Apoptosis 18, 286-299, 2013 | 47 | 2013 |
| Loss of SDHB promotes dysregulated iron homeostasis, oxidative stress, and sensitivity to ascorbate J Goncalves, S Moog, A Morin, G Gentric, S Müller, AP Morrell, ... Cancer Research 81 (13), 3480-3494, 2021 | 30 | 2021 |
| PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma A D’Avola, N Legrave, M Tajan, P Chakravarty, RL Shearer, HW King, ... The Journal of clinical investigation 132 (9), 2022 | 16 | 2022 |
| B-cell receptor signaling induced metabolic alterations in chronic lymphocytic leukemia can be partially bypassed by TP53 Abnormalities K Kluckova, AJ Clear, A D’Avola, LZ Rassenti, TJ Kipps, JG Gribben, ... HemaSphere 6 (6), e722, 2022 | 7 | 2022 |
| Advances in understanding of metabolism of B-cell lymphoma: implications for therapy K Kluckova, A D’Avola, JC Riches Cancers 14 (22), 5552, 2022 | 5 | 2022 |
