| Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo D Salani, G Taraboletti, L Rosanò, V Di Castro, P Borsotti, R Giavazzi, ... The American journal of pathology 157 (5), 1703-1711, 2000 | 458 | 2000 |
| Endothelin 1 in cancer: biological implications and therapeutic opportunities L Rosanò, F Spinella, A Bagnato Nature Reviews Cancer 13 (9), 637-651, 2013 | 328 | 2013 |
| Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1α in ovarian carcinoma cells F Spinella, L Rosanò, V Di Castro, PG Natali, A Bagnato Journal of Biological Chemistry 277 (31), 27850-27855, 2002 | 312 | 2002 |
| Role of endothelin-1 in neovascularization of ovarian carcinoma D Salani, V Di Castro, MR Nicotra, L Rosanò, R Tecce, A Venuti, ... The American journal of pathology 157 (5), 1537-1547, 2000 | 265 | 2000 |
| The endothelin axis in cancer A Bagnato, L Rosanò The international journal of biochemistry & cell biology 40 (8), 1443-1451, 2008 | 251 | 2008 |
| Endothelin-1 promotes epithelial-to-mesenchymal transition in human ovarian cancer cells L Rosanò, F Spinella, V Di Castro, MR Nicotra, S Dedhar, AG de Herreros, ... Cancer research 65 (24), 11649-11657, 2005 | 228 | 2005 |
| Acquisition of chemoresistance and EMT phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells L Rosanò, R Cianfrocca, F Spinella, V Di Castro, MR Nicotra, A Lucidi, ... Clinical cancer research 17 (8), 2350-2360, 2011 | 215 | 2011 |
| Endothelin-1 induces tumor proteinase activation and invasiveness of ovarian carcinoma cells L Rosano, M Varmi, D Salani, V Di Castro, F Spinella, PG Natali, ... Cancer Research 61 (22), 8340-8346, 2001 | 207 | 2001 |
| β-Arrestin links endothelin A receptor to β-catenin signaling to induce ovarian cancer cell invasion and metastasis L Rosanò, R Cianfrocca, S Masi, F Spinella, V Di Castro, A Biroccio, ... Proceedings of the National Academy of Sciences 106 (8), 2806-2811, 2009 | 197 | 2009 |
| Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation D Del Bufalo, V Di Castro, A Biroccio, M Varmi, D Salani, L Rosanò, ... Molecular Pharmacology 61 (3), 524-532, 2002 | 188 | 2002 |
| Therapeutic targeting of the endothelin a receptor in human ovarian carcinoma L Rosano, F Spinella, D Salani, V Di Castro, A Venuti, MR Nicotra, ... Cancer Research 63 (10), 2447-2453, 2003 | 157 | 2003 |
| Endothelin B receptor blockade inhibits dynamics of cell interactions and communications in melanoma cell progression A Bagnato, L Rosanò, F Spinella, V Di Castro, R Tecce, PG Natali Cancer research 64 (4), 1436-1443, 2004 | 156 | 2004 |
| Endothelin-1-induced prostaglandin E2-EP2, EP4 signaling regulates vascular endothelial growth factor production and ovarian carcinoma cell invasion F Spinella, L Rosanò, V Di Castro, PG Natali, A Bagnato Journal of Biological Chemistry 279 (45), 46700-46705, 2004 | 136 | 2004 |
| Endothelin-1 stimulates lymphatic endothelial cells and lymphatic vessels to grow and invade F Spinella, E Garrafa, V Di Castro, L Rosano, MR Nicotra, A Caruso, ... Cancer Research 69 (6), 2669-2676, 2009 | 126 | 2009 |
| Emerging role of the endothelin axis in ovarian tumor progression A Bagnato, F Spinella, L Rosano Endocrine-Related Cancer 12 (4), 761-772, 2005 | 123 | 2005 |
| The endothelin axis in cancer: the promise and the challenges of molecularly targeted therapy A Bagnato, F Spinella, L Rosano Canadian journal of physiology and pharmacology 86 (8), 473-484, 2008 | 121 | 2008 |
| Endothelin-1 and endothelin-3 promote invasive behavior via hypoxia-inducible factor-1α in human melanoma cells F Spinella, L Rosano, V Di Castro, S Decandia, MR Nicotra, PG Natali, ... Cancer research 67 (4), 1725-1734, 2007 | 117 | 2007 |
| Green tea polyphenol epigallocatechin-3-gallate inhibits the endothelin axis and downstream signaling pathways in ovarian carcinoma F Spinella, L Rosano, V Di Castro, S Decandia, A Albini, MR Nicotra, ... Molecular cancer therapeutics 5 (6), 1483-1492, 2006 | 114 | 2006 |
| Endothelin-1 decreases gap junctional intercellular communication by inducing phosphorylation of connexin 43 in human ovarian carcinoma cells F Spinella, L Rosanò, V Di Castro, MR Nicotra, PG Natali, A Bagnato Journal of Biological Chemistry 278 (42), 41294-41301, 2003 | 102 | 2003 |
| Endothelin A receptor/β-arrestin signaling to the Wnt pathway renders ovarian cancer cells resistant to chemotherapy L Rosano, R Cianfrocca, P Tocci, F Spinella, V Di Castro, V Caprara, ... Cancer research 74 (24), 7453-7464, 2014 | 100 | 2014 |
