Robert J. Mallis
Robert J. Mallis
Dana Farber Cancer Institute
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Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A
KN Brazin, RJ Mallis, DB Fulton, AH Andreotti
Proceedings of the National Academy of Sciences 99 (4), 1899-1904, 2002
Oxidative modification of H-ras: S-thiolation and S-nitrosylation of reactive cysteines
RJ Mallis, JE Buss, JA Thomas
Biochemical Journal 355 (1), 145-153, 2001
Aging and oxidation of reactive protein sulfhydryls
JA Thomas, RJ Mallis
Experimental gerontology 36 (9), 1519-1526, 2001
Structural characterization of a proline-driven conformational switch within the Itk SH2 domain
RJ Mallis, KN Brazin, DB Fulton, AH Andreotti
Nature structural biology 9 (12), 900-905, 2002
Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime
DK Das, Y Feng, RJ Mallis, X Li, DB Keskin, RE Hussey, SK Brady, ...
Proceedings of the National Academy of Sciences 112 (5), 1517-1522, 2015
Irreversible thiol oxidation in carbonic anhydrase III: protection by S-glutathiolation and detection in aging rats
RJ Mallis, MJ Hamann, W Zhao, T Zhang, S Hendrich, JA Thomas
Biological chemistry 383 (3-4), 649-662, 2002
Crystal structure of S‐glutathiolated carbonic anhydrase III
RJ Mallis, BW Poland, TK Chatterjee, RA Fisher, S Darmawan, ...
FEBS letters 482 (3), 237-241, 2000
TCR mechanobiology: torques and tunable structures linked to early T cell signaling
ST Kim, Y Shin, K Brazin, RJ Mallis, J Sun, G Wagner, M Lang, ...
Frontiers in immunology 3, 76, 2012
Mechanosensing drives acuity of αβ T-cell recognition
Y Feng, KN Brazin, E Kobayashi, RJ Mallis, EL Reinherz, MJ Lang
Proceedings of the National Academy of Sciences 114 (39), E8204-E8213, 2017
Effect of S-nitrosothiols on cellular glutathione and reactive protein sulfhydryls
RJ Mallis, JA Thomas
Archives of biochemistry and biophysics 383 (1), 60-69, 2000
Pre-TCR ligand binding impacts thymocyte development before αβTCR expression
RJ Mallis, K Bai, H Arthanari, RE Hussey, M Handley, Z Li, L Chingozha, ...
Proceedings of the National Academy of Sciences 112 (27), 8373-8378, 2015
Structural features of the αβTCR mechanotransduction apparatus that promote pMHC discrimination
KN Brazin, RJ Mallis, DK Das, Y Feng, W Hwang, J Wang, G Wagner, ...
Frontiers in immunology 6, 441, 2015
CTL recognition of a protective immunodominant influenza A virus nucleoprotein epitope utilizes a highly restricted Vβ but diverse Vα repertoire: functional and structural …
W Zhong, SB Dixit, RJ Mallis, H Arthanari, AA Lugovskoy, DL Beveridge, ...
Journal of molecular biology 372 (2), 535-548, 2007
The T cell antigen receptor α transmembrane domain coordinates triggering through regulation of bilayer immersion and CD3 subunit associations
KN Brazin, RJ Mallis, A Boeszoermenyi, Y Feng, A Yoshizawa, PA Reche, ...
Immunity 49 (5), 829-841. e6, 2018
Pre-T cell receptors (Pre-TCRs) leverage Vβ complementarity determining regions (CDRs) and hydrophobic patch in mechanosensing thymic self-ligands
DK Das, RJ Mallis, JS Duke-Cohan, RE Hussey, PW Tetteh, M Hilton, ...
Journal of Biological Chemistry 291 (49), 25292-25305, 2016
Cryopreservation of rooster semen in thirteen and sixteen percent glycerol
SPS Gill, EG Buss, RJ Mallis
Poultry science 75 (2), 254-256, 1996
Constitutively oxidized CXXC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments
KN Brazin, RJ Mallis, C Li, DB Keskin, H Arthanari, Y Gao, SL Wu, ...
Journal of Biological Chemistry 289 (27), 18880-18892, 2014
Protein S-thiolation, S-nitrosylation, and irreversible sulfhydryl oxidation: roles in redox regulation
JA Thomas, R Mallis, H Sies
Cell Implic Redox Signaling, 141-174, 2003
A conserved hydrophobic patch on Vβ domains revealed by TCRβ chain crystal structures: Implications for pre-TCR dimerization
B Zhou, Q Chen, R Mallis, H Zhang, J Liu, EL Reinherz, J Wang
Frontiers in immunology 2, 5, 2011
NMR: an essential structural tool for integrative studies of T cell development, pMHC ligand recognition and TCR mechanobiology
RJ Mallis, KN Brazin, JS Duke-Cohan, W Hwang, J Wang, G Wagner, ...
Journal of biomolecular NMR 73 (6), 319-332, 2019
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