| Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis G D'Orazi, B Cecchinelli, T Bruno, I Manni, Y Higashimoto, S Saito, ... Nature cell biology 4 (1), 11-19, 2002 | 848 | 2002 |
| p53 expression in B-cell chronic lymphocytic leukemia: a marker of disease progression and poor prognosis I Cordone, S Masi, FR Mauro, S Soddu, O Morsilli, T Valentini, ML Vegna, ... Blood, The Journal of the American Society of Hematology 91 (11), 4342-4349, 1998 | 308 | 1998 |
| MDM2-regulated degradation of HIPK2 prevents p53Ser46 phosphorylation and DNA damage-induced apoptosis C Rinaldo, A Prodosmo, F Mancini, S Iacovelli, A Sacchi, F Moretti, ... Molecular cell 25 (5), 739-750, 2007 | 227 | 2007 |
| p53 inhibits α6β4 integrin survival signaling by promoting the caspase 3–dependent cleavage of AKT/PKB RE Bachelder, MJ Ribick, A Marchetti, R Falcioni, S Soddu, KR Davis, ... The Journal of cell biology 147 (5), 1063-1072, 1999 | 217 | 1999 |
| NF-Y Mediates the Transcriptional Inhibition of thecyclin B1, cyclin B2, and cdc25CPromoters upon Induced G2 Arrest I Manni, G Mazzaro, A Gurtner, R Mantovani, U Haugwitz, K Krause, ... Journal of Biological Chemistry 276 (8), 5570-5576, 2001 | 214 | 2001 |
| p53 re-expression inhibits proliferation and restores differentiation of human thyroid anaplastic carcinoma cells F Moretti, A Farsetti, S Soddu, S Misiti, M Crescenzi, S Filetti, M Andreoli, ... Oncogene 14 (6), 729-740, 1997 | 196 | 1997 |
| TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity R Tomasini, AA Samir, A Carrier, D Isnardon, B Cecchinelli, S Soddu, ... Journal of Biological Chemistry 278 (39), 37722-37729, 2003 | 192 | 2003 |
| Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways B Valentinis, G Romano, F Peruzzi, A Morrione, M Prisco, S Soddu, ... Journal of Biological Chemistry 274 (18), 12423-12430, 1999 | 180 | 1999 |
| Interference with p53 protein inhibits hematopoietic and muscle differentiation. S Soddu, G Blandino, R Scardigli, S Coen, A Marchetti, MG Rizzo, ... The Journal of cell biology 134 (1), 193-204, 1996 | 162 | 1996 |
| Variants of uncertain significance in the era of high-throughput genome sequencing: a lesson from breast and ovary cancers G Federici, S Soddu Journal of Experimental & Clinical Cancer Research 39, 1-12, 2020 | 158 | 2020 |
| p53 displacement from centrosomes and p53-mediated G1 arrest following transient inhibition of the mitotic spindle M Ciciarello, R Mangiacasale, M Casenghi, MZ Limongi, M D'Angelo, ... Journal of Biological Chemistry 276 (22), 19205-19213, 2001 | 152 | 2001 |
| Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint T Bruno, F De Nicola, S Iezzi, D Lecis, C D'Angelo, M Di Padova, N Corbi, ... Cancer cell 10 (6), 473-486, 2006 | 146 | 2006 |
| p53 regulates myogenesis by triggering the differentiation activity of pRb A Porrello, MA Cerone, S Coen, A Gurtner, G Fontemaggi, L Cimino, ... The Journal of cell biology 151 (6), 1295-1304, 2000 | 145 | 2000 |
| From p63 to p53 across p73 S Strano, M Rossi, G Fontemaggi, E Munarriz, S Soddu, A Sacchi, ... FEBS letters 490 (3), 163-170, 2001 | 144 | 2001 |
| HIPK2: a multitalented partner for transcription factors in DNA damage response and development C Rinaldo, A Prodosmo, F Siepi, S Soddu Biochemistry and Cell Biology 85 (4), 411-418, 2007 | 135 | 2007 |
| Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis B Cecchinelli, L Lavra, C Rinaldo, S Iacovelli, A Gurtner, A Gasbarri, ... Molecular and cellular biology 26 (12), 4746-4757, 2006 | 131 | 2006 |
| p53 localization at centrosomes during mitosis and postmitotic checkpoint are ATM-dependent and require serine 15 phosphorylation A Tritarelli, E Oricchio, M Ciciarello, R Mangiacasale, A Palena, P Lavia, ... Molecular biology of the cell 15 (8), 3751-3757, 2004 | 121 | 2004 |
| Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis V Di Stefano, C Rinaldo, A Sacchi, S Soddu, G D'Orazi Experimental cell research 293 (2), 311-320, 2004 | 119 | 2004 |
| High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2 GM Pierantoni, C Rinaldo, M Mottolese, A Di Benedetto, F Esposito, ... The Journal of clinical investigation 117 (3), 693-702, 2007 | 117 | 2007 |
| Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation R Amato, L D’Antona, G Porciatti, V Agosti, M Menniti, C Rinaldo, N Costa, ... Journal of molecular medicine 87, 1221-1239, 2009 | 115 | 2009 |
