Mitochondrial DNA in inflammation and immunity JS Riley, SWG Tait EMBO reports 21 (4), e49799, 2020 | 532 | 2020 |
Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death G Ichim, J Lopez, SU Ahmed, N Muthalagu, E Giampazolias, ME Delgado, ... Molecular cell 57 (5), 860-872, 2015 | 398 | 2015 |
Mitochondrial inner membrane permeabilisation enables mt DNA release during apoptosis JS Riley, G Quarato, C Cloix, J Lopez, J O'Prey, M Pearson, J Chapman, ... The EMBO journal 37 (17), e99238, 2018 | 364 | 2018 |
Parkin-independent mitophagy controls chemotherapeutic response in cancer cells E Villa, E Proïcs, C Rubio-Patiño, S Obba, B Zunino, JP Bossowski, ... Cell reports 20 (12), 2846-2859, 2017 | 246 | 2017 |
Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis E Kerr, C Holohan, KM McLaughlin, J Majkut, S Dolan, K Redmond, ... Cell Death & Differentiation 19 (8), 1317-1327, 2012 | 109 | 2012 |
Differential affinity of FLIP and procaspase 8 for FADD’s DED binding surfaces regulates DISC assembly J Majkut, M Sgobba, C Holohan, N Crawford, AE Logan, E Kerr, ... Nature communications 5 (1), 3350, 2014 | 96 | 2014 |
Prognostic and therapeutic relevance of FLIP and procaspase-8 overexpression in non-small cell lung cancer JS Riley, R Hutchinson, DG McArt, N Crawford, C Holohan, I Paul, ... Cell death & disease 4 (12), e951-e951, 2013 | 78 | 2013 |
Mito-priming as a method to engineer Bcl-2 addiction J Lopez, M Bessou, JS Riley, E Giampazolias, F Todt, T Rochegüe, ... Nature Communications 7 (1), 10538, 2016 | 64 | 2016 |
DED or alive: assembly and regulation of the death effector domain complexes JS Riley, A Malik, C Holohan, DB Longley Cell death & disease 6 (8), e1866-e1866, 2015 | 63 | 2015 |
Apoptotic stress causes mtDNA release during senescence and drives the SASP S Victorelli, H Salmonowicz, J Chapman, H Martini, MG Vizioli, JS Riley, ... Nature 622 (7983), 627-636, 2023 | 58 | 2023 |
PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasiveness N Rabas, S Palmer, L Mitchell, S Ismail, A Gohlke, JS Riley, SWG Tait, ... Journal of Cell Biology 220 (12), e202006049, 2021 | 58 | 2021 |
Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage K Cao, JS Riley, R Heilig, AE Montes-Gómez, E Vringer, K Berthenet, ... Developmental cell 57 (10), 1211-1225. e6, 2022 | 41 | 2022 |
Efficient drug delivery and induction of apoptosis in colorectal tumors using a death receptor 5-targeted nanomedicine D Schmid, F Fay, DM Small, J Jaworski, JS Riley, D Tegazzini, C Fenning, ... Molecular Therapy 22 (12), 2083-2092, 2014 | 39 | 2014 |
Modulating mitofusins to control mitochondrial function and signaling E Zacharioudakis, B Agianian, V Kumar MV, N Biris, TP Garner, ... Nature communications 13 (1), 3775, 2022 | 38 | 2022 |
When cell death goes wrong: inflammatory outcomes of failed apoptosis and mitotic cell death FJ Bock, JS Riley Cell Death & Differentiation 30 (2), 293-303, 2023 | 22 | 2023 |
The SCFSkp2 ubiquitin ligase complex modulates TRAIL-R2-induced apoptosis by regulating FLIP(L) JZ Roberts, C Holohan, T Sessler, J Fox, N Crawford, JS Riley, ... Cell Death & Differentiation 27 (9), 2726-2741, 2020 | 19 | 2020 |
Mitochondria and pathogen immunity: from killer to firestarter JS Riley, SWG Tait The EMBO Journal 38 (11), e102325, 2019 | 12 | 2019 |
Mechanisms of mitophagy: putting the powerhouse into the doghouse JS Riley, SWG Tait Biological chemistry 397 (7), 617-635, 2016 | 11 | 2016 |
Activated BAX/BAK enable mitochondrial inner membrane permeabilisation and mtDNA release during cell death JS Riley, G Quarato, J Lopez, J O’Prey, M Pearson, J Chapman, H Sesaki, ... bioRxiv, 272104, 2018 | 9 | 2018 |
Voices from beyond the grave: the impact of apoptosis on the microenvironment JS Riley, FJ Bock Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1869 (11), 119341, 2022 | 7 | 2022 |