Giorgio Sesti
Giorgio Sesti
Full Professor of Internal Medicine-Sapienza University of Rome
Verified email at
Cited by
Cited by
Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
JB Buse, J Rosenstock, G Sesti, WE Schmidt, E Montanya, JH Brett, ...
The Lancet 374 (9683), 39-47, 2009
Basal insulin and cardiovascular and other outcomes in dysglycemia
OT Investigators
New England Journal of Medicine 367 (4), 319-328, 2012
N-3 fatty acids and cardiovascular outcomes in patients with dysglycemia
OT Investigators
New England Journal of Medicine 367 (4), 309-318, 2012
Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
The Lancet 292 (10157), 1519-1529, 2018
Cardiovascular efficacy and safety of bococizumab in high-risk patients
SCO Investigators
New England Journal of Medicine 376 (16), 1527-1539, 2017
Defects of the insulin receptor substrate (IRS) system in human metabolic disorders
G Sesti, M Federici, ML Hribal, D Lauro, P Sbraccia, R Lauro
The FASEB Journal 15 (12), 2099-2111, 2001
High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program
M Federici, M Hribal, L Perego, M Ranalli, Z Caradonna, C Perego, ...
Diabetes 50 (6), 1290-1301, 2001
Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells
M Federici, R Menghini, A Mauriello, ML Hribal, F Ferrelli, D Lauro, ...
Circulation 106 (4), 466-472, 2002
Pathophysiology of insulin resistance
G Sesti
Best practice & research Clinical endocrinology & metabolism 20 (4), 665-679, 2006
Uric acid and endothelial dysfunction in essential hypertension
C Zoccali, R Maio, F Mallamaci, G Sesti, F Perticone
Journal of the American Society of Nephrology 17 (5), 1466-1471, 2006
Asymmetric dimethylarginine, L-arginine, and endothelial dysfunction in essential hypertension
F Perticone, A Sciacqua, R Maio, M Perticone, R Maas, RH Boger, ...
Journal of the American College of Cardiology 46 (3), 518-523, 2005
Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in …
F Andreozzi, E Laratta, A Sciacqua, F Perticone, G Sesti
Circulation research 94 (9), 1211-1218, 2004
Pulse pressure and endothelial dysfunction in never-treated hypertensive patients
R Ceravolo, R Maio, A Pujia, A Sciacqua, G Ventura, MC Costa, G Sesti, ...
Journal of the American College of Cardiology 41 (10), 1753-1758, 2003
Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: the ORIGIN Trial (Outcome …
BJ Origin Trial Investigators, Gerstein H, Yusuf S, Riddle MC, Ryden L
Am Heart J 155 (1), 26-32, 2008
Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential
B Giovannone, M Lucia Scaldaferri, M Federici, O Porzio, D Lauro, ...
Diabetes/metabolism research and reviews 16 (6), 434-441, 2000
The Gly972→Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic β cells
O Porzio, M Federici, ML Hribal, D Lauro, D Accili, R Lauro, P Borboni, ...
The Journal of clinical investigation 104 (3), 357-364, 1999
Switching to once-daily liraglutide from twice-daily exenatide further improves glycemic control in patients with type 2 diabetes using oral agents
JB Buse, G Sesti, WE Schmidt, E Montanya, CT Chang, Y Xu, L Blonde, ...
Diabetes care 33 (6), 1300-1303, 2010
Insulin receptor substrate 1 mediates the stimulatory effect of insulin on GLUT4 translocation in transfected rat adipose cells.
MJ Quon, AJ Butte, MJ Zarnowski, G Sesti, SW Cushman, SI Taylor
Journal of Biological Chemistry 269 (45), 27920-27924, 1994
A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects
G Sesti, M Cardellini, MA Marini, S Frontoni, M D’Adamo, S Del Guerra, ...
Diabetes 52 (5), 1280-1283, 2003
Plasma concentration of IGF-I is independently associated with insulin sensitivity in subjects with different degrees of glucose tolerance
G Sesti, A Sciacqua, M Cardellini, MA Marini, R Maio, M Vatrano, ...
Diabetes care 28 (1), 120-125, 2005
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