A surface expression vector for antibody screening F Breitling, S Dübel, T Seehaus, I Klewinghaus, M Little Gene 104 (2), 147-153, 1991 | 458 | 1991 |
A helper phage to improve single-chain antibody presentation in phage display S Rondot, J Koch, F Breitling, S Dübel Nature biotechnology 19 (1), 75-78, 2001 | 419 | 2001 |
Targeting Recombinant Antibodies to the Surface of Escherichia coli: Fusion to a Peptidoglycan Associated Lipoprotein P Fuchs, F Breitling, S Dübel, T Seehaus, M Little Bio/technology 9 (12), 1369-1372, 1991 | 267 | 1991 |
Recombinant single-chain Fv fragments carrying C-terminal cysteine residues: production of bivalent and biotinylated miniantibodies SM Kipriyanov, S Dübel, F Breitling, RE Kontermann, M Little Molecular immunology 31 (14), 1047-1058, 1994 | 225 | 1994 |
DMBT1 Encodes a Protein Involved in the Immune Defense and in Epithelial Differentiation and Is Highly Unstable in Cancer J Mollenhauer, S Herbertz, U Holmskov, M Tolnay, I Krebs, A Merlo, ... Cancer research 60 (6), 1704-1710, 2000 | 214 | 2000 |
Single-chain antibody streptavidin fusions: tetrameric bifunctional scFv-complexes with biotin binding activity and enhanced affinity to antigen SM Kipriyanov, F Breitling, M Little, S Dübel Human Antibodies 6 (3), 93-101, 1995 | 180 | 1995 |
Combinatorial synthesis of peptide arrays onto a microchip M Beyer, A Nesterov, I Block, K König, T Felgenhauer, S Fernandez, ... Science 318 (5858), 1888-1888, 2007 | 179 | 2007 |
Carboxy-terminal regions on the surface of tubulin and microtubules epitope locations of YOL1/34, DM1A and DM1B F Breitling, M Little Journal of molecular biology 189 (2), 367-370, 1986 | 175 | 1986 |
Combinatorial synthesis of peptide arrays with a laser printer V Stadler, T Felgenhauer, M Beyer, S Fernandez, K Leibe, S Güttler, ... Angewandte Chemie International Edition 47 (37), 7132-7135, 2008 | 170 | 2008 |
Bifunctional and multimeric complexes of streptavidin fused to single chain antibodies (scFv) S Dübel, F Breitling, R Kontermann, T Schmidt, A Skerra, M Little Journal of immunological methods 178 (2), 201-209, 1995 | 170 | 1995 |
Affinity enhancement of a recombinant antibody: formation of complexes with multiple valency by a single-chain Fv fragment–core streptavidin fusion SM Kipriyanov, M Little, H Kropshofer, F Breitling, S Gotter, S Dübel Protein Engineering, Design and Selection 9 (2), 203-211, 1996 | 134 | 1996 |
The antigen-binding domain of a human IgG-anti-F(ab′)2 autoantibody M Welschof, P Terness, SM Kipriyanov, D Stanescu, F Breitling, H Dörsam, ... Proceedings of the National Academy of Sciences 94 (5), 1902-1907, 1997 | 123 | 1997 |
A novel glass slide-based peptide array support with high functionality resisting non-specific protein adsorption M Beyer, T Felgenhauer, FR Bischoff, F Breitling, V Stadler Biomaterials 27 (18), 3505-3514, 2006 | 117 | 2006 |
Effects of unpaired cysteines on yield, solubility and activity of different recombinant antibody constructs expressed in E. coli A Schmiedl, F Breitling, CH Winter, I Queitsch, S Dübel Journal of immunological methods 242 (1-2), 101-114, 2000 | 107 | 2000 |
Bacterial surface presentation of proteins and peptides: an alternative to phage technology? M Little, P Fuchs, F Breitling, S Dübel Trends in biotechnology 11 (1), 3-5, 1993 | 96 | 1993 |
A family of vectors for surface display and production of antibodies S Dübel, F Breitling, P Fuchs, M Braunagel, I Klewinghaus, M Little Gene 128 (1), 97-101, 1993 | 92 | 1993 |
Isolation of IgG antibody Fv-DNA from various mouse and rat hybridoma cell lines using the polymerase chain reaction with a simple set of primers S Dübel, F Breitling, P Fuchs, M Zewe, S Gotter, M Welschof, ... Journal of immunological methods 175 (1), 89-95, 1994 | 89 | 1994 |
High-density peptide arrays F Breitling, A Nesterov, V Stadler, T Felgenhauer, FR Bischoff Molecular BioSystems 5 (3), 224-234, 2009 | 87 | 2009 |
Simultaneous mutagenesis of antibody CDR regions by overlap extension and PCR. N Hayashi, M Welschof, M Zewe, M Braunagel, S Dübel, F Breitling, ... Biotechniques 17 (2), 310, 312, 314-5, 1994 | 84 | 1994 |
Preparation and use of gene banks of synthetic human antibodies (" synthetic human-antibody libraries") M Little, FB Breitling, T Seehaus, S Dubel, I Klewinghaus US Patent 5,840,479, 1998 | 82 | 1998 |