| Digital signaling and hysteresis characterize ras activation in lymphoid cells J Das, M Ho, J Zikherman, C Govern, M Yang, A Weiss, AK Chakraborty, ... Cell 136 (2), 337-351, 2009 | 476 | 2009 |
| Endogenous antigen tunes the responsiveness of naive B cells but not T cells J Zikherman, R Parameswaran, A Weiss Nature 489 (7414), 160-164, 2012 | 345 | 2012 |
| CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cells ML Hermiston, J Zikherman, JW Zhu Immunological reviews 228 (1), 288-311, 2009 | 216 | 2009 |
| PTPN22 deficiency cooperates with the CD45 E613R allele to break tolerance on a non-autoimmune background J Zikherman, M Hermiston, D Steiner, K Hasegawa, A Chan, A Weiss The Journal of Immunology 182 (7), 4093-4106, 2009 | 174 | 2009 |
| A sharp T-cell antigen receptor signaling threshold for T-cell proliferation BB Au-Yeung, J Zikherman, JL Mueller, JF Ashouri, M Matloubian, ... Proceedings of the National Academy of Sciences 111 (35), E3679-E3688, 2014 | 163 | 2014 |
| IL-2 modulates the TCR signaling threshold for CD8 but not CD4 T cell proliferation on a single-cell level BB Au-Yeung, GA Smith, JL Mueller, CS Heyn, RG Jaszczak, A Weiss, ... The Journal of Immunology 198 (6), 2445-2456, 2017 | 124 | 2017 |
| Tonic signals: why do lymphocytes bother? DR Myers, J Zikherman, JP Roose Trends in immunology 38 (11), 844-857, 2017 | 123 | 2017 |
| CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development J Zikherman, C Jenne, S Watson, K Doan, W Raschke, CC Goodnow, ... Immunity 32 (3), 342-354, 2010 | 113 | 2010 |
| IgM and IgD B cell receptors differentially respond to endogenous antigens and control B cell fate M Noviski, JL Mueller, A Satterthwaite, LA Garrett-Sinha, F Brombacher, ... Elife 7, e35074, 2018 | 89 | 2018 |
| Cutting edge: An in vivo reporter reveals active B cell receptor signaling in the germinal center J Mueller, M Matloubian, J Zikherman The Journal of Immunology 194 (7), 2993-2997, 2015 | 85 | 2015 |
| Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases S Mukherjee, J Zhu, J Zikherman, R Parameswaran, TA Kadlecek, ... Science signaling 6 (256), ra1-ra1, 2013 | 84 | 2013 |
| Long‐term corticosteroid‐sparing immunosuppression for cardiac sarcoidosis DG Rosenthal, P Parwani, TO Murray, BJ Petek, BS Benn, T De Marco, ... Journal of the American Heart Association 8 (18), e010952, 2019 | 75 | 2019 |
| Origin of the sharp boundary that discriminates positive and negative selection of thymocytes A Prasad, J Zikherman, J Das, JP Roose, A Weiss, AK Chakraborty Proceedings of the National Academy of Sciences 106 (2), 528-533, 2009 | 75 | 2009 |
| Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development BB Au-Yeung, HJ Melichar, JO Ross, DA Cheng, J Zikherman, KM Shokat, ... Nature immunology 15 (7), 687-694, 2014 | 72 | 2014 |
| Quantitative differences in CD45 expression unmask functions for CD45 in B-cell development, tolerance, and survival J Zikherman, K Doan, R Parameswaran, W Raschke, A Weiss Proceedings of the National Academy of Sciences 109 (1), E3-E12, 2012 | 64 | 2012 |
| NR4A nuclear receptors restrain B cell responses to antigen when second signals are absent or limiting C Tan, R Hiwa, JL Mueller, V Vykunta, K Hibiya, M Noviski, J Huizar, ... Nature immunology 21 (10), 1267-1279, 2020 | 60 | 2020 |
| The role of T cell receptor signaling thresholds in guiding T cell fate decisions J Zikherman, B Au-Yeung Current opinion in immunology 33, 43-48, 2015 | 56 | 2015 |
| Alternative splicing of CD45: the tip of the iceberg J Zikherman, A Weiss Immunity 29 (6), 839-841, 2008 | 47 | 2008 |
| An extracatalytic function of CD45 in B cells is mediated by CD22 S Coughlin, M Noviski, JL Mueller, A Chuwonpad, WC Raschke, A Weiss, ... Proceedings of the National Academy of Sciences 112 (47), E6515-E6524, 2015 | 45 | 2015 |
| Self‐reactivity on a spectrum: A sliding scale of peripheral B cell tolerance C Tan, M Noviski, J Huizar, J Zikherman Immunological reviews 292 (1), 37-60, 2019 | 41 | 2019 |
Byron Au-YeungAssistant Professor, Department of Medicine, Emory UniversityVerified email at emory.edu
