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Iris Grossman-Haham
Iris Grossman-Haham
Email verificata su bgu.ac.il
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Citata da
Citata da
Anno
A secreted disulfide catalyst controls extracellular matrix composition and function
T Ilani, A Alon, I Grossman, B Horowitz, E Kartvelishvily, SR Cohen, ...
Science 341 (6141), 74-76, 2013
1632013
The dynamic disulphide relay of quiescin sulphydryl oxidase
A Alon, I Grossman, Y Gat, VK Kodali, F DiMaio, T Mehlman, G Haran, ...
Nature 488 (7411), 414-418, 2012
912012
Structure of the radial spoke head and insights into its role in mechanoregulation of ciliary beating
I Grossman-Haham, N Coudray, Z Yu, F Wang, N Zhang, G Bhabha, ...
Nature structural & molecular biology 28 (1), 20-28, 2021
392021
Slow domain reconfiguration causes power-law kinetics in a two-state enzyme
I Grossman-Haham, G Rosenblum, T Namani, H Hofmann
Proceedings of the National Academy of Sciences 115 (3), 513-518, 2018
352018
An inhibitory antibody blocks the first step in the dithiol/disulfide relay mechanism of the enzyme QSOX1
I Grossman, A Alon, T Ilani, D Fass
Journal of molecular biology 425 (22), 4366-4378, 2013
342013
Enzyme structure captures four cysteines aligned for disulfide relay
Y Gat, A Vardi‐Kilshtain, I Grossman, DT Major, D Fass
Protein Science 23 (8), 1102-1112, 2014
192014
Single-molecule spectroscopy exposes hidden states in an enzymatic electron relay
I Grossman, H Yuval Aviram, G Armony, A Horovitz, H Hofmann, G Haran, ...
Nature Communications 6 (1), 8624, 2015
182015
Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models
T Feldman, I Grossman-Haham, Y Elkis, P Vilela, N Moskovits, I Barshack, ...
Oncotarget 11 (4), 386, 2020
172020
cis‐Proline mutants of quiescin sulfhydryl oxidase 1 with altered redox properties undermine extracellular matrix integrity and cell adhesion in fibroblast cultures
G Javitt, I Grossman‐Haham, A Alon, E Resnick, Y Mutsafi, T Ilani, D Fass
Protein Science 28 (1), 228-238, 2019
132019
Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma
I Grossman, T Ilani, SJ Fleishman, D Fass
Protein Engineering, Design and Selection 29 (4), 135-147, 2016
132016
Towards an atomic model of a beating ciliary axoneme
I Grossman-Haham
Current Opinion in Structural Biology 78, 102516, 2023
52023
Compositions for inhibition of quiescin sulfhydryl oxidase (qsox1) and uses of same
D Fass, I Grossman, T Ilani, A Alon
US Patent App. 15/494,585, 2017
12017
Chimeric quiescin sulfhydryl oxidase (qsox1) antibodies and uses of same
D Fass, S Fleishman, S Warszawski, I Grossman, L Khmelnitsky
US Patent App. 17/267,049, 2021
2021
Antibodies targeting quiescin sulfhydryl oxidase (qsox1) and uses of same
D Fass, I Grossman, T Ilani
US Patent App. 17/087,765, 2021
2021
Antibodies targeting quiescin sulfhydryl oxidase (QSOX1) and uses of same
D Fass, I Grossman, T Ilani
US Patent 10,829,561, 2020
2020
Correction: Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models
T Feldman, I Grossman-Haham, Y Elkis, P Vilela, N Moskovits, I Barshack, ...
Oncotarget 11 (40), 3687, 2020
2020
Compositions for inhibition of quiescin sulfhydryl oxidase (QSOX1) and uses of same
D Fass, I Grossman, T Ilani, A Alon
US Patent 9,631,028, 2017
2017
Mechanism and inhibition of the enzyme QSOX, catalyst of basement membrane modulation in cancer
I Grossman-Haham
PQDT-Global, 2017
2017
An Inhibitory Antibody Targeting the Disulfide Catalyst QSOX1 Perturbs Extracellular Matrix Formation by Blocking the First Step in a Dithiol/Disulfide Relay: 526
I Grossman, A Alon, T Ilani, D Fass
Protein Science 22, 2013
2013
Supplementary Information for
I Grossman, T Ilani, SJ Fleishman, D Fass
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