Ursula Grohmann
Ursula Grohmann
Professore di Farmacologia, Università di Perugia
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Modulation of tryptophan catabolism by regulatory T cells
F Fallarino, U Grohmann, KW Hwang, C Orabona, C Vacca, R Bianchi, ...
Nature immunology 4 (12), 1206-1212, 2003
CTLA-4–Ig regulates tryptophan catabolism in vivo
U Grohmann, C Orabona, F Fallarino, C Vacca, F Calcinaro, A Falorni, ...
Nature immunology 3 (11), 1097-1101, 2002
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor ζ-chain and induce a regulatory phenotype in naive T cells
F Fallarino, U Grohmann, S You, BC McGrath, DR Cavener, C Vacca, ...
The Journal of Immunology 176 (11), 6752-6761, 2006
T cell apoptosis by tryptophan catabolism
F Fallarino, U Grohmann, C Vacca, R Bianchi, C Orabona, A Spreca, ...
Cell Death & Differentiation 9 (10), 1069-1077, 2002
Tolerance, DCs and tryptophan: much ado about IDO
U Grohmann, F Fallarino, P Puccetti
Trends in immunology 24 (5), 242-248, 2003
Indoleamine 2, 3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells
MT Pallotta, C Orabona, C Volpi, C Vacca, ML Belladonna, R Bianchi, ...
Nature immunology 12 (9), 870-878, 2011
Aryl hydrocarbon receptor control of a disease tolerance defence pathway
A Bessede, M Gargaro, MT Pallotta, D Matino, G Servillo, C Brunacci, ...
Nature 511 (7508), 184-190, 2014
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease
L Romani, F Fallarino, A De Luca, C Montagnoli, C D’Angelo, T Zelante, ...
Nature 451 (7175), 211-215, 2008
IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-κB activation
P Puccetti, U Grohmann
Nature Reviews Immunology 7 (10), 817-823, 2007
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86
C Orabona, U Grohmann, ML Belladonna, F Fallarino, C Vacca, R Bianchi, ...
Nature immunology 5 (11), 1134-1142, 2004
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy
U Grohmann, C Volpi, F Fallarino, S Bozza, R Bianchi, C Vacca, ...
Nature medicine 13 (5), 579-586, 2007
IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells
ML Belladonna, JC Renauld, R Bianchi, C Vacca, F Fallarino, C Orabona, ...
The Journal of Immunology 168 (11), 5448-5454, 2002
IL-12 acts directly on DC to promote nuclear localization of NF-κB and primes DC for IL-12 production
U Grohmann, ML Belladonna, R Bianchi, C Orabona, E Ayroldi, ...
Immunity 9 (3), 315-323, 1998
Functional expression of indoleamine 2, 3-dioxygenase by murine CD8α+ dendritic cells
F Fallarino, C Vacca, C Orabona, ML Belladonna, R Bianchi, B Marshall, ...
International Immunology 14 (1), 65-68, 2002
Control of immune response by amino acid metabolism
U Grohmann, V Bronte
Immunological reviews 236 (1), 243-264, 2010
Murine plasmacytoid dendritic cells initiate the immunosuppressive pathway of tryptophan catabolism in response to CD200 receptor engagement
F Fallarino, C Asselin-Paturel, C Vacca, R Bianchi, S Gizzi, MC Fioretti, ...
The Journal of Immunology 173 (6), 3748-3754, 2004
A relay pathway between arginine and tryptophan metabolism confers immunosuppressive properties on dendritic cells
G Mondanelli, R Bianchi, MT Pallotta, C Orabona, E Albini, A Iacono, ...
Immunity 46 (2), 233-244, 2017
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice
U Grohmann, F Fallarino, R Bianchi, C Orabona, C Vacca, MC Fioretti, ...
The Journal of experimental medicine 198 (1), 153-160, 2003
T cell apoptosis by kynurenines
F Fallarino, U Grohmann, C Vacca, C Orabona, A Spreca, MC Fioretti, ...
Developments in tryptophan and serotonin metabolism, 183-190, 2003
Neutralizing antibody to interleukin 4 induces systemic protection and T helper type 1-associated immunity in murine candidiasis.
L Romani, A Mencacci, U Grohmann, S Mocci, P Mosci, P Puccetti, ...
The Journal of experimental medicine 176 (1), 19-25, 1992
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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