IL-22 upregulates epithelial claudin-2 to drive diarrhea and enteric pathogen clearance PY Tsai, B Zhang, WQ He, JM Zha, MA Odenwald, G Singh, A Tamura, ... Cell host & microbe 21 (6), 671-681. e4, 2017 | 214 | 2017 |
The tight junction protein ZO-1 is dispensable for barrier function but critical for effective mucosal repair WT Kuo, L Zuo, MA Odenwald, S Madha, G Singh, CB Gurniak, ... Gastroenterology 161 (6), 1924-1939, 2021 | 179 | 2021 |
Inflammation-induced occludin downregulation limits epithelial apoptosis by suppressing caspase-3 expression WT Kuo, L Shen, L Zuo, N Shashikanth, MLDM Ong, L Wu, J Zha, ... Gastroenterology 157 (5), 1323-1337, 2019 | 158 | 2019 |
Resistance to hypoxia-induced necroptosis is conferred by glycolytic pyruvate scavenging of mitochondrial superoxide in colorectal cancer cells CY Huang, WT Kuo, YC Huang, TC Lee, LCH Yu Cell death & disease 4 (5), e622-e622, 2013 | 121 | 2013 |
Tight junctions as targets and effectors of mucosal immune homeostasis L Zuo, WT Kuo, JR Turner Cellular and molecular gastroenterology and hepatology 10 (2), 327-340, 2020 | 113 | 2020 |
Tight junction proteins occludin and ZO‐1 as regulators of epithelial proliferation and survival WT Kuo, MA Odenwald, JR Turner, L Zuo Annals of the New York Academy of Sciences 1514 (1), 21-33, 2022 | 112 | 2022 |
Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experimental colitis in mice P Raju, N Shashikanth, PY Tsai, P Pongkorpsakol, S Chanez-Paredes, ... The Journal of Clinical Investigation 130 (10), 5197-5208, 2020 | 95 | 2020 |
Interleukin 22 expands transit-amplifying cells while depleting Lgr5+ stem cells via inhibition of Wnt and notch signaling JM Zha, HS Li, Q Lin, WT Kuo, ZH Jiang, PY Tsai, N Ding, J Wu, SF Xu, ... Cellular and molecular gastroenterology and hepatology 7 (2), 255-274, 2019 | 92 | 2019 |
The scaffolding protein ZO-1 coordinates actomyosin and epithelial apical specializations in vitro and in vivo MA Odenwald, W Choi, WT Kuo, G Singh, A Sailer, Y Wang, L Shen, ... Journal of Biological Chemistry 293 (45), 17317-17335, 2018 | 84 | 2018 |
Enteric dysbiosis promotes antibiotic-resistant bacterial infection: systemic dissemination of resistant and commensal bacteria through epithelial transcytosis LCH Yu, YA Shih, LL Wu, YD Lin, WT Kuo, WH Peng, KS Lu, SC Wei, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 307 (8 …, 2014 | 78 | 2014 |
SGLT-1-mediated glucose uptake protects human intestinal epithelial cells against Giardia duodenalis-induced apoptosis CH Linda, C Huang, W Kuo, H Sayer, JR Turner, AG Buret International journal for parasitology 38 (8-9), 923-934, 2008 | 76 | 2008 |
Commensal bacterial endocytosis in epithelial cells is dependent on myosin light chain kinase–activated brush border fanning by interferon-γ LL Wu, WH Peng, WT Kuo, CY Huang, YH Ni, KS Lu, JR Turner, CH Linda The American Journal of Pathology 184 (8), 2260-2274, 2014 | 53 | 2014 |
LPS receptor subunits have antagonistic roles in epithelial apoptosis and colonic carcinogenesis WT Kuo, TC Lee, HY Yang, CY Chen, YC Au, YZ Lu, LL Wu, SC Wei, ... Cell Death & Differentiation 22 (10), 1590-1604, 2015 | 52 | 2015 |
Eritoran suppresses colon cancer by altering a functional balance in toll-like receptors that bind lipopolysaccharide WT Kuo, TC Lee, LCH Yu Cancer research 76 (16), 4684-4695, 2016 | 51 | 2016 |
Distinct cytoprotective roles of pyruvate and ATP by glucose metabolism on epithelial necroptosis and crypt proliferation in ischaemic gut CY Huang, WT Kuo, CY Huang, TC Lee, CT Chen, WH Peng, KS Lu, ... The Journal of physiology 595 (2), 505-521, 2017 | 41 | 2017 |
Differentiating between tight junction-dependent and tight junction-independent intestinal barrier loss in vivo SD Chanez-Paredes, S Abtahi, WT Kuo, JR Turner Permeability Barrier: Methods and Protocols, 249-271, 2021 | 32 | 2021 |
The Villin1 gene promoter drives Cre recombinase expression in extraintestinal tissues M Rutlin, D Rastelli, WT Kuo, JA Estep, A Louis, MM Riccomagno, ... Cellular and molecular gastroenterology and hepatology 10 (4), 864-867. e5, 2020 | 22 | 2020 |
Tumor necrosis factor α-dependent neutrophil priming prevents intestinal ischemia/reperfusion-induced bacterial translocation YZ Lu, CY Huang, YC Huang, TC Lee, WT Kuo, YC Pai, LCH Yu Digestive Diseases and Sciences 62, 1498-1510, 2017 | 15 | 2017 |
Tacrolimus-binding protein FKBP8 directs myosin light chain kinase-dependent barrier regulation and is a potential therapeutic target in Crohn’s disease L Zuo, WT Kuo, F Cao, SD Chanez-Paredes, D Zeve, P Mannam, ... Gut 72 (5), 870-881, 2023 | 13 | 2023 |
Myosin light chain kinase is a potential target for hypopharyngeal cancer treatment F Cao, L Zhu, J Zhang, P Pongkorpsakol, WT Kuo, JR Turner, Q Zhou, ... Biomedicine & Pharmacotherapy 131, 110665, 2020 | 5 | 2020 |