Tommi Henrik Nyrönen
Tommi Henrik Nyrönen
CSC - IT Center for Science Ltd.
Email verificata su - Home page
Citata da
Citata da
BODIL: a molecular modeling environment for structure-function analysis and drug design
JV Lehtonen, DJ Still, J Ekholm, D Björklund, Z Iftikhar, M Huhtala, S Repo, ...
Journal of computer-aided molecular design 18 (6), 401-419, 2004
An in silico approach to discovering novel inhibitors of human sirtuin type 2
AJ Tervo, S Kyrylenko, P Niskanen, A Salminen, J Leppänen, TH Nyrönen, ...
Journal of medicinal chemistry 47 (25), 6292-6298, 2004
Glucuronidation converts clopidogrel to a strong time‐dependent inhibitor of CYP2C8: a phase II metabolite as a perpetrator of drug–drug interactions
A Tornio, AM Filppula, O Kailari, M Neuvonen, TH Nyrönen, T Tapaninen, ...
Clinical Pharmacology & Therapeutics 96 (4), 498-507, 2014
Molecular mechanism for agonist-promoted α2A-adrenoceptor activation by norepinephrine and epinephrine
T Nyrönen, M Pihlavisto, JM Peltonen, AM Hoffrén, M Varis, T Salminen, ...
Molecular Pharmacology 59 (5), 1343-1354, 2001
Bioinformatics training: a review of challenges, actions and support requirements
MV Schneider, J Watson, T Attwood, K Rother, A Budd, J McDowall, A Via, ...
Briefings in bioinformatics 11 (6), 544-551, 2010
Molecular evolution of adrenoceptors and dopamine receptors: implications for the binding of catecholamines
H Xhaard, VV Rantanen, T Nyrönen, MS Johnson
Journal of medicinal chemistry 49 (5), 1706-1719, 2006
Best practices in bioinformatics training for life scientists
A Via, T Blicher, E Bongcam-Rudloff, MD Brazas, C Brooksbank, A Budd, ...
Briefings in bioinformatics 14 (5), 528-537, 2013
Three-dimensional structure− activity relationships of nonsteroidal ligands in complex with androgen receptor ligand-binding domain
AA Söderholm, PT Lehtovuori, TH Nyrönen
Journal of medicinal chemistry 48 (4), 917-925, 2005
BRUTUS: optimization of a grid-based similarity function for rigid-body molecular superposition. 1. Alignment and virtual screening applications
AJ Tervo, T Rönkkö, TH Nyrönen, A Poso
Journal of medicinal chemistry 48 (12), 4076-4086, 2005
A structure-activity relationship study of catechol-O-methyltransferase inhibitors combining molecular docking and 3D QSAR methods
AJ Tervo, TH Nyrönen, T Rönkkö, A Poso
Journal of Computer-Aided Molecular Design 17 (12), 797-810, 2003
Three-dimensional models of α2A-adrenergic receptor complexes provide a structural explanation for ligand binding
T Salminen, M Varis, T Nyrönen, M Pihlavisto, AM Hoffrén, T Lönnberg, ...
Journal of Biological Chemistry 274 (33), 23405-23413, 1999
Federated identity management for research collaborations
D Broeder, B Jones, D Kelsey, P Kershaw, S Lüders, A Lyall, T Nyrönen, ...
Report No. CERN-OPEN 6, 2012
Molecular mechanisms of ligand–receptor interactions in transmembrane domain V of the α2A‐adrenoceptor
JM Peltonen, T Nyrönen, S Wurster, M Pihlavisto, AM Hoffrén, ...
British journal of pharmacology 140 (2), 347-358, 2003
Comparing the quality and predictiveness between 3D QSAR models obtained from manual and automated alignment
AJ Tervo, TH Nyrönen, T Rönkkö, A Poso
Journal of chemical information and computer sciences 44 (3), 807-816, 2004
Model structures of α-2 adrenoceptors in complex with automatically docked antagonist ligands raise the possibility of interactions dissimilar from agonist ligands
H Xhaard, T Nyrönen, VV Rantanen, JO Ruuskanen, J Laurila, ...
Journal of structural biology 150 (2), 126-143, 2005
“RKKH” Peptides from the Snake Venom Metalloproteinase ofBothrops jararaca Bind Near the Metal Ion-dependent Adhesion Site of the Human Integrin α2 I-domain
O Pentikäinen, AM Hoffrén, J Ivaska, J Käpylä, T Nyrönen, J Heino, ...
Journal of Biological Chemistry 274 (44), 31493-31505, 1999
Leveraging European infrastructures to access 1 million human genomes by 2022
G Saunders, M Baudis, R Becker, S Beltran, C Béroud, E Birney, ...
Nature Reviews Genetics 20 (11), 693-701, 2019
Bioinformatics Training Network (BTN): a community resource for bioinformatics trainers
MV Schneider, P Walter, MC Blatter, J Watson, MD Brazas, K Rother, ...
Briefings in Bioinformatics, 2011
Small molecule designed to target metal binding site in the α2I domain inhibits integrin function
J Käpylä, OT Pentikäinen, T Nyrönen, L Nissinen, S Lassander, J Jokinen, ...
Journal of medicinal chemistry 50 (11), 2742-2746, 2007
A linear open-chain piperazine-pyridine ligand and its meso-helical Co complex
K Airola, J Ratilainen, T Nyrönen, K Rissanen
Inorganica chimica acta 277 (1), 55-60, 1998
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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