| mCSM: predicting the effects of mutations in proteins using graph-based signatures DEV Pires, DB Ascher, TL Blundell Bioinformatics 30 (3), 335-342, 2014 | 355 | 2014 |
| pkCSM: predicting small-molecule pharmacokinetic and toxicity properties using graph-based signatures DEV Pires, TL Blundell, DB Ascher Journal of medicinal chemistry 58 (9), 4066-4072, 2015 | 336 | 2015 |
| DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach DEV Pires, DB Ascher, TL Blundell Nucleic acids research 42 (W1), W314-W319, 2014 | 308 | 2014 |
| DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability CHM Rodrigues, DEV Pires, DB Ascher Nucleic acids research 46 (W1), W350-W355, 2018 | 102 | 2018 |
| Protein cutoff scanning: A comparative analysis of cutoff dependent and cutoff free methods for prospecting contacts in proteins CH da Silveira, DEV Pires, RC Minardi, C Ribeiro, CJM Veloso, ... Proteins: Structure, Function, and Bioinformatics 74 (3), 727-743, 2009 | 79 | 2009 |
| Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance J Phelan, F Coll, R McNerney, DB Ascher, DEV Pires, N Furnham, ... BMC medicine 14 (1), 1-13, 2016 | 71 | 2016 |
| mCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistance DEV Pires, TL Blundell, DB Ascher Scientific reports 6, 29575, 2016 | 63 | 2016 |
| Tumour risks and genotype–phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD KA Andrews, DB Ascher, DEV Pires, DR Barnes, L Vialard, RT Casey, ... Journal of medical genetics 55 (6), 384-394, 2018 | 61 | 2018 |
| In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity DEV Pires, J Chen, TL Blundell, DB Ascher Scientific reports 6, 19848, 2016 | 61 | 2016 |
| Twelve novel HGD gene variants identified in 99 alkaptonuria patients: focus on ‘black bone disease’in Italy M Nemethova, J Radvanszky, L Kadasi, DB Ascher, DEV Pires, ... European Journal of Human Genetics 24 (1), 66-72, 2016 | 61 | 2016 |
| Platinum: a database of experimentally measured effects of mutations on structurally defined protein–ligand complexes DEV Pires, TL Blundell, DB Ascher Nucleic acids research 43 (D1), D387-D391, 2015 | 60 | 2015 |
| Germline mutations in the CDKN2B tumor suppressor gene predispose to renal cell carcinoma M Jafri, NC Wake, DB Ascher, DEV Pires, D Gentle, MR Morris, ... Cancer discovery 5 (7), 723-729, 2015 | 54 | 2015 |
| A campaign-based characterization of spamming strategies PH Calais, DEV Pires, DO Guedes, W Meira Jr, C Hoepers, KS Jessen | 53 | 2008 |
| CSM-lig: a web server for assessing and comparing protein–small molecule affinities DEV Pires, DB Ascher Nucleic acids research 44 (W1), W557-W561, 2016 | 52 | 2016 |
| mCSM-AB: a web server for predicting antibody–antigen affinity changes upon mutation with graph-based signatures DEV Pires, DB Ascher Nucleic acids research 44 (W1), W469-W473, 2016 | 43 | 2016 |
| Cutoff Scanning Matrix (CSM): structural classification and function prediction by protein inter-residue distance patterns DEV Pires, RC de Melo-Minardi, MA dos Santos, CH da Silveira, ... BMC Genomics 12 (Suppl 4), S12, 2011 | 39 | 2011 |
| mCSM–NA: predicting the effects of mutations on protein–nucleic acids interactions DEV Pires, DB Ascher Nucleic acids research 45 (W1), W241-W246, 2017 | 37 | 2017 |
| Analysis of HGD gene mutations in patients with alkaptonuria from the United Kingdom: identification of novel mutations JL Usher, DB Ascher, DEV Pires, AM Milan, TL Blundell, LR Ranganath JIMD Reports, Volume 24, 3-11, 2014 | 34 | 2014 |
| SDHA related tumorigenesis: a new case series and literature review for variant interpretation and pathogenicity RT Casey, DB Ascher, E Rattenberry, L Izatt, KA Andrews, HL Simpson, ... Molecular genetics & genomic medicine 5 (3), 237-250, 2017 | 30 | 2017 |
| Variation in Human Cytochrome P-450 Drug-Metabolism Genes: A Gateway to the Understanding of Plasmodium vivax Relapses ACR Silvino, GL Costa, FCF Araújo, DB Ascher, DEV Pires, CJF Fontes, ... PloS one 11 (7), e0160172, 2016 | 30 | 2016 |
David AscherBaker Institute; University of Melbourne; University of CambridgeVerified email at unimelb.edu.au
