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Oneda Leka
Oneda Leka
Postdoctoral fellow, Paul Scherrer Institute
Verified email at psi.ch
Title
Cited by
Cited by
Year
On the translocation of botulinum and tetanus neurotoxins across the membrane of acidic intracellular compartments
M Pirazzini, O Leka, G Zanetti, O Rossetto, C Montecucco
Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (3), 467-474, 2016
1062016
The first non Clostridial botulinum-like toxin cleaves VAMP within the juxtamembrane domain
I Zornetta, D Azarnia Tehran, G Arrigoni, F Anniballi, L Bano, O Leka, ...
Scientific reports 6 (1), 30257, 2016
1042016
Hsp90 is involved in the entry of clostridial neurotoxins into the cytosol of nerve terminals
D Azarnia Tehran, M Pirazzini, O Leka, A Mattarei, F Lista, T Binz, ...
Cellular Microbiology 19 (2), e12647, 2017
472017
Diphtheria toxin conformational switching at acidic pH
O Leka, F Vallese, M Pirazzini, P Berto, C Montecucco, G Zanotti
The FEBS journal 281 (9), 2115-2122, 2014
402014
A novel inhibitor prevents the peripheral neuroparalysis of botulinum neurotoxins
D Azarnia Tehran, G Zanetti, O Leka, F Lista, S Fillo, T Binz, CC Shone, ...
Scientific Reports 5 (1), 17513, 2015
342015
Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice
M Pirazzini, A Grinzato, D Corti, S Barbieri, O Leka, F Vallese, M Tonellato, ...
The Journal of Clinical Investigation 131 (22), 2021
82021
Crystal structure of the catalytic domain of botulinum neurotoxin subtype A3
O Leka, Y Wu, X Li, RA Kammerer
Journal of Biological Chemistry 296, 2021
72021
Structural insights into the interaction of botulinum neurotoxin a with its neuronal receptor SV2C
X Li, C Brunner, Y Wu, O Leka, G Schneider, RA Kammerer
Toxicon 175, 36-43, 2020
22020
A DARPin promotes faster onset of botulinum neurotoxin A1 action
O Leka, Y Wu, G Zanetti, S Furler, T Reinberg, J Marinho, JV Schaefer, ...
Nature Communications 14 (1), 8317, 2023
2023
A coiled-coil-based design strategy for the thermostabilization of G-protein-coupled receptors
M Amer, O Leka, P Jasko, D Frey, X Li, RA Kammerer
Scientific Reports 13 (1), 10159, 2023
2023
A DARPin Increases the Catalytic Activity of Botulinum Neurotoxin A1
O Leka, Y Wu, G Zanetti, S Furler, T Reinberg, J Marinho, J Schaefer, ...
2023
Antigen-Binding Fragments From Purified Human Monoclonal Antibodies Open to the Intrathecal Therapy of Tetanus
F Fabris, P Šoštarić, P Meglić, T Marika, G Alessandro, C Davide, ...
Toxins 2022 6th International Conference, s61-s62, 2022
2022
Extremely potent Human Monoclonal Antibodies for the Prophylaxis and Therapy of Tetanus
M Pirazzini, A Grinzato, D Corti, S Barbieri, O Leka, F Vallese, M Tonellato, ...
bioRxiv, 2021.05. 24.445390, 2021
2021
Blocking tetanus with purified human monoclonal antibodies
M Pirazzini, S Barbieri, A Grinzato, O Leka, F Vallese, G Zanetti, ...
Toxicon 190, S60-S60, 2021
2021
Hsp90, thioredoxin and thioredoxin reductase form a chaperone-redox machinery enabling the catalytic activity of clostridial neurotoxins inside nerve terminals
M Pirazzini, DA Tehran, G Zanetti, O Leka, A Mattarei, T Binz, R Lista, ...
JOURNAL OF NEUROCHEMISTRY 142, 217-217, 2017
2017
Hsp90 is involved in the entry of clostridial neurotoxins into the cytosol of nerve terminals.
M Pirazzini, O Leka, A Mattarei, F Lista, T Binz, O Rossetto, C Montecucco
Cellular Microbiology 19 (2), 2016
2016
Structural and functional characterization of AB toxins: diphtheria toxin and clostridial neurotoxins
O Leka
Università degli studi di Padova, 2016
2016
169. A WEISSELLA ORYZAE BOTULINUM-LIKE TOXIN CLEAVES VAMP WITHIN THE JUXTAMEMBRANE DOMAIN
C Montecucco, I Zornetta, G Arrigoni, F Anniballi, L Bano, O Leka, ...
Abstracts/Toxicon 123 (S2eS90), S2eS90, 2016
2016
Hsp90, thioredoxin, and thioredoxin reductase form a chaperone-redox machinery enabling the catalytic activity of clostridial neurotoxins inside nerve terminals
M Pirazzini, G Zanetti, O Leka, T Binz, F Lista, A Mattarei, O Rossetto, ...
Toxicon, S68, 2016
2016
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