An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors I Ben-Porath, MW Thomson, VJ Carey, R Ge, GW Bell, A Regev, ... Nature genetics 40 (5), 499, 2008 | 2870 | 2008 |
Engineering customized cell sensing and response behaviors using synthetic notch receptors L Morsut, KT Roybal, X Xiong, RM Gordley, SM Coyle, M Thomson, ... Cell 164 (4), 780-791, 2016 | 843 | 2016 |
Pluripotency factors in embryonic stem cells regulate differentiation into germ layers M Thomson, SJ Liu, LN Zou, Z Smith, A Meissner, S Ramanathan Cell 145 (6), 875-889, 2011 | 668 | 2011 |
Unlimited multistability in multisite phosphorylation systems M Thomson, J Gunawardena Nature 460 (7252), 274, 2009 | 270 | 2009 |
Transcriptome-wide analysis reveals hallmarks of human intestine development and maturation in vitro and in vivo SR Finkbeiner, DR Hill, CH Altheim, PH Dedhia, MJ Taylor, YH Tsai, ... Stem cell reports 4 (6), 1140-1155, 2015 | 236 | 2015 |
Adult neurogenesis is sustained by symmetric self-renewal and differentiation K Obernier, A Cebrian-Silla, M Thomson, JI Parraguez, R Anderson, ... Cell stem cell 22 (2), 221-234. e8, 2018 | 234 | 2018 |
Low Dimensionality in Gene Expression Data Enables the Accurate Extraction of Transcriptional Programs from Shallow Sequencing G Heimberg, R Bhatnagar, H El-Samad, M Thomson Cell systems 2 (4), 239-250, 2016 | 171 | 2016 |
Controlling organization and forces in active matter through optically defined boundaries TD Ross, HJ Lee, Z Qu, RA Banks, R Phillips, M Thomson Nature 572 (7768), 224-229, 2019 | 120 | 2019 |
A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity AE Cerchiari, JC Garbe, NY Jee, ME Todhunter, KE Broaders, DM Peehl, ... Proceedings of the National Academy of Sciences 112 (7), 2287-2292, 2015 | 112 | 2015 |
The rational parameterisation theorem for multisite post-translational modification systems M Thomson, J Gunawardena Journal of theoretical biology 261 (4), 626-636, 2009 | 107 | 2009 |
Highly multiplexed single-cell RNA-seq by DNA oligonucleotide tagging of cellular proteins J Gehring, JH Park, S Chen, M Thomson, L Pachter Nature biotechnology 38 (1), 35-38, 2020 | 100 | 2020 |
Programming with models: modularity and abstraction provide powerful capabilities for systems biology A Mallavarapu, M Thomson, B Ullian, J Gunawardena Journal of The Royal Society Interface 6 (32), 257-270, 2008 | 100 | 2008 |
In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development YH Tsai, R Nattiv, PH Dedhia, MS Nagy, AM Chin, M Thomson, OD Klein, ... Development 144 (6), 1045-1055, 2017 | 96 | 2017 |
Transcription Factor Competition Allows Embryonic Stem Cells to Distinguish Authentic Signals from Noise C Sokolik, Y Liu, D Bauer, J McPherson, M Broeker, G Heimberg, LS Qi, ... Cell Systems 1 (2), 117-129, 2015 | 82 | 2015 |
Developmental clock and mechanism of de novo polarization of the mouse embryo M Zhu, J Cornwall-Scoones, P Wang, CE Handford, J Na, M Thomson, ... Science 370 (6522), 2020 | 72 | 2020 |
SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells SA Myers, S Peddada, N Chatterjee, T Friedrich, K Tomoda, G Krings, ... Elife 5, e10647, 2016 | 71 | 2016 |
A DNA-repair pathway can affect transcriptional noise to promote cell fate transitions RV Desai, X Chen, B Martin, S Chaturvedi, DW Hwang, W Li, C Yu, ... Science, 2021 | 63 | 2021 |
Diffusion as a ruler: modeling kinesin diffusion as a length sensor for intraflagellar transport NL Hendel, M Thomson, WF Marshall Biophysical journal 114 (3), 663-674, 2018 | 57 | 2018 |
Deep parallel characterization of AAV tropism and AAV-mediated transcriptional changes via single-cell RNA sequencing D Brown, M Altermatt, T Dobreva, S Chen, A Wang, M Thomson, ... Frontiers in Immunology 12, 2021 | 43 | 2021 |
Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension M Bao, J Cornwall-Scoones, E Sanchez-Vasquez, DY Chen, J De Jonghe, ... Nature cell biology 24 (9), 1341-1349, 2022 | 35 | 2022 |