| Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand R Ochoa-Sanchez, S Comai, B Lacoste, FR Bambico, ... Journal of Neuroscience 31 (50), 18439-18452, 2011 | 155 | 2011 |
| Plant-derived phenolic compounds prevent the DNA single-strand breakage and cytotoxicity induced by tert-butylhydroperoxide via an iron-chelating mechanism P Sestili, G Diamantini, A Bedini, L Cerioni, I Tommasini, G Tarzia, ... Biochemical Journal 364 (1), 121-128, 2002 | 133 | 2002 |
| 2-[N-Acylamino(C1−C3)alkyl]indoles as MT1 Melatonin Receptor Partial Agonists, Antagonists, and Putative Inverse Agonists G Spadoni, C Balsamini, A Bedini, G Diamantini, B Di Giacomo, A Tontini, ... Journal of medicinal chemistry 41 (19), 3624-3634, 1998 | 128 | 1998 |
| N-(Substituted-anilinoethyl)amides: Design, Synthesis, and Pharmacological Characterization of a New Class of Melatonin Receptor Ligands S Rivara, A Lodola, M Mor, A Bedini, G Spadoni, V Lucini, M Pannacci, ... Journal of medicinal chemistry 50 (26), 6618-6626, 2007 | 104 | 2007 |
| Selective melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways M Lopez-Canul, E Palazzo, S Dominguez-Lopez, L Luongo, B Lacoste, ... Pain 156 (2), 305-317, 2015 | 99 | 2015 |
| Analysis of Structure−Activity Relationships for MT2 Selective Antagonists by Melatonin MT1 and MT2 Receptor Models S Rivara, S Lorenzi, M Mor, PV Plazzi, G Spadoni, A Bedini, G Tarzia Journal of medicinal chemistry 48 (12), 4049-4060, 2005 | 93 | 2005 |
| Anxiolytic effects of the melatonin MT2 receptor partial agonist UCM765: Comparison with melatonin and diazepam R Ochoa-Sanchez, Q Rainer, S Comai, G Spadoni, A Bedini, S Rivara, ... Progress in neuro-psychopharmacology and biological psychiatry 39 (2), 318-325, 2012 | 91 | 2012 |
| Rapid and transient stimulation of intracellular reactive oxygen species by melatonin in normal and tumor leukocytes F Radogna, L Paternoster, M De Nicola, C Cerella, S Ammendola, ... Toxicology and applied pharmacology 239 (1), 37-45, 2009 | 85 | 2009 |
| Melatonin receptor agonists: new options for insomnia and depression treatment G Spadoni, A Bedini, S Rivara, M Mor CNS neuroscience & therapeutics 17 (6), 733-741, 2011 | 82 | 2011 |
| Synthesis of tryptamine derivatives via a direct, one-pot reductive alkylation of indoles M Righi, F Topi, S Bartolucci, A Bedini, G Piersanti, G Spadoni The Journal of Organic Chemistry 77 (14), 6351-6357, 2012 | 78 | 2012 |
| Melatonin receptor agonists: SAR and applications to the treatment of sleep-wake disorders S Rivara, M Mor, A Bedini, G Spadoni, G Tarzia Current topics in medicinal chemistry 8 (11), 954-968, 2008 | 77 | 2008 |
| Iridium-catalyzed direct synthesis of tryptamine derivatives from indoles: exploiting N-protected β-amino alcohols as alkylating agents S Bartolucci, M Mari, A Bedini, G Piersanti, G Spadoni The Journal of Organic Chemistry 80 (6), 3217-3222, 2015 | 71 | 2015 |
| Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands M Mor, G Spadoni, B Di Giacomo, G Diamantini, A Bedini, G Tarzia, ... Bioorganic & medicinal chemistry 9 (4), 1045-1057, 2001 | 68 | 2001 |
| Recent advances in the development of melatonin MT1 and MT2 receptor agonists M Mor, S Rivara, D Pala, A Bedini, G Spadoni, G Tarzia Expert opinion on therapeutic patents 20 (8), 1059-1077, 2010 | 66 | 2010 |
| Three-Dimensional Quantitative Structure−Activity Relationship Studies on Selected MT1 and MT2 Melatonin Receptor Ligands: Requirements for Subtype … S Rivara, M Mor, C Silva, V Zuliani, F Vacondio, G Spadoni, A Bedini, ... Journal of medicinal chemistry 46 (8), 1429-1439, 2003 | 64 | 2003 |
| Indole‐based analogs of melatonin: in vitro antioxidant and cytoprotective activities M Mor, C Silva, F Vacondio, PV Plazzi, S Bertoni, G Spadoni, ... Journal of pineal research 36 (2), 95-102, 2004 | 63 | 2004 |
| Therapeutic uses of melatonin and melatonin derivatives: a patent review (2012-2014) S Rivara, D Pala, A Bedini, G Spadoni Expert opinion on therapeutic patents, 425-441, 2015 | 61 | 2015 |
| Homology models of melatonin receptors: challenges and recent advances D Pala, A Lodola, A Bedini, G Spadoni, S Rivara International Journal of Molecular Sciences 14 (4), 8093-8121, 2013 | 59 | 2013 |
| Antiproliferative and pro-apoptotic activity of melatonin analogues on melanoma and breast cancer cells G Gatti, V Lucini, S Dugnani, A Calastretti, G Spadoni, A Bedini, S Rivara, ... Oncotarget 8 (40), 68338, 2017 | 58 | 2017 |
| Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines G Spadoni, A Bedini, S Lucarini, M Mari, DH Caignard, JA Boutin, ... Journal of Medicinal Chemistry 58 (18), 7512-7525, 2015 | 57 | 2015 |
