Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis M Caganova, C Carrisi, G Varano, F Mainoldi, F Zanardi, PL Germain, ... The Journal of clinical investigation 123 (12), 5009-5022, 2013 | 227 | 2013 |
Exploratory rearing: a context-and stress-sensitive behavior recorded in the open-field test O Sturman, PL Germain, J Bohacek Stress 21 (5), 443-452, 2018 | 210 | 2018 |
Multi-omic measurements of heterogeneity in HeLa cells across laboratories Y Liu, Y Mi, T Mueller, S Kreibich, EG Williams, A Van Drogen, C Borel, ... Nature biotechnology 37 (3), 314-322, 2019 | 181 | 2019 |
7q11. 23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages A Adamo, S Atashpaz, PL Germain, M Zanella, G D'Agostino, V Albertin, ... Nature genetics 47 (2), 132-141, 2015 | 134 | 2015 |
Muscat detects subpopulation-specific state transitions from multi-sample multi-condition single-cell transcriptomics data HL Crowell, C Soneson, PL Germain, D Calini, L Collin, C Raposo, ... Nature communications 11 (1), 1-12, 2020 | 119* | 2020 |
Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal trauma K Gapp, G van Steenwyk, PL Germain, W Matsushima, KLM Rudolph, ... Molecular Psychiatry 25 (9), 2162-2174, 2020 | 104 | 2020 |
YY1 haploinsufficiency causes an intellectual disability syndrome featuring transcriptional and chromatin dysfunction M Gabriele, AT Vulto-van Silfhout, PL Germain, A Vitriolo, R Kumar, ... The American Journal of Human Genetics 100 (6), 907-925, 2017 | 95 | 2017 |
Systematic proteome and proteostasis profiling in human Trisomy 21 fibroblast cells Y Liu, C Borel, L Li, T Müller, EG Williams, PL Germain, M Buljan, T Sajic, ... Nature communications 8 (1), 1-15, 2017 | 78 | 2017 |
Junk or functional DNA? ENCODE and the function controversy PL Germain, E Ratti, F Boem Biology & Philosophy 29 (6), 807-831, 2014 | 73 | 2014 |
Taming human genetic variability: transcriptomic meta-analysis guides the experimental design and interpretation of iPSC-based disease modeling PL Germain, G Testa Stem Cell Reports 8 (6), 1784-1796, 2017 | 70 | 2017 |
Cell reprogramming requires silencing of a core subset of polycomb targets G Fragola, PL Germain, P Laise, A Cuomo, A Blasimme, F Gross, ... PLoS genetics 9 (2), e1003292, 2013 | 66 | 2013 |
Dosage analysis of the 7q11.23 Williams region identifies BAZ1B as a major human gene patterning the modern human face and underlying self-domestication M Zanella, A Vitriolo, A Andirko, PT Martins, S Sturm, T O’Rourke, ... Science advances 5 (12), eaaw7908, 2019 | 64 | 2019 |
RNAontheBENCH: computational and empirical resources for benchmarking RNAseq quantification and differential expression methods PL Germain, A Vitriolo, A Adamo, P Laise, V Das, G Testa Nucleic acids research 44 (11), 5054-5067, 2016 | 50 | 2016 |
hLGDB: a database of human lysosomal genes and their regulation A Brozzi, L Urbanelli, P Luc Germain, A Magini, C Emiliani Database 2013, 2013 | 46 | 2013 |
Cancer cells and adaptive explanations PL Germain Biology & philosophy 27 (6), 785-810, 2012 | 44 | 2012 |
From cohorts to molecules: Adverse impacts of endocrine disrupting mixtures N Caporale, M Leemans, L Birgersson, PL Germain, C Cheroni, ... Science 375 (6582), eabe8244, 2022 | 39* | 2022 |
pipeComp, a general framework for the evaluation of computational pipelines, reveals performant single cell RNA-seq preprocessing tools PL Germain, A Sonrel, MD Robinson Genome Biology 21 (1), 1-28, 2020 | 35 | 2020 |
KMT2B is selectively required for neuronal transdifferentiation, and its loss exposes dystonia candidate genes G Barbagiovanni, PL Germain, M Zech, S Atashpaz, PL Riso, ... Cell reports 25 (4), 988-1001, 2018 | 23 | 2018 |
Involvement of circulating factors in the transmission of paternal experiences through the germline G van Steenwyk, K Gapp, A Jawaid, PL Germain, F Manuella, DK Tanwar, ... The EMBO journal 39 (23), e104579, 2020 | 22* | 2020 |
Doublet identification in single-cell sequencing data using scDblFinder PL Germain, A Lun, CG Meixide, W Macnair, MD Robinson F1000Research 10, 2021 | 20 | 2021 |