| mCSM: predicting the effects of mutations in proteins using graph-based signatures DEV Pires, DB Ascher, TL Blundell Bioinformatics 30 (3), 335-342, 2014 | 369 | 2014 |
| pkCSM: predicting small-molecule pharmacokinetic and toxicity properties using graph-based signatures DEV Pires, TL Blundell, DB Ascher Journal of medicinal chemistry 58 (9), 4066-4072, 2015 | 361 | 2015 |
| DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach DEV Pires, DB Ascher, TL Blundell Nucleic acids research 42 (W1), W314-W319, 2014 | 323 | 2014 |
| SDM: a server for predicting effects of mutations on protein stability AP Pandurangan, B Ochoa-Montaņo, DB Ascher, TL Blundell Nucleic acids research 45 (W1), W229-W235, 2017 | 142 | 2017 |
| Arpeggio: a web server for calculating and visualising interatomic interactions in protein structures HC Jubb, AP Higueruelo, B Ochoa-Montaņo, WR Pitt, DB Ascher, ... Journal of molecular biology 429 (3), 365-371, 2017 | 124 | 2017 |
| DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability CHM Rodrigues, DEV Pires, DB Ascher Nucleic acids research 46 (W1), W350-W355, 2018 | 119 | 2018 |
| Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA DB Ascher, J Wielens, TL Nero, L Doughty, CJ Morton, MW Parker Scientific reports 4, 4765, 2014 | 99 | 2014 |
| Identification and characterization of a new cognitive enhancer based on inhibition of insulin‐regulated aminopeptidase AL Albiston, CJ Morton, HL Ng, V Pham, HR Yeatman, S Ye, ... The FASEB Journal 22 (12), 4209-4217, 2008 | 94 | 2008 |
| DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair BL Sibanda, DY Chirgadze, DB Ascher, TL Blundell Science 355 (6324), 520-524, 2017 | 89 | 2017 |
| Flexibility and small pockets at protein–protein interfaces: new insights into druggability H Jubb, TL Blundell, DB Ascher Progress in biophysics and molecular biology 119 (1), 2-9, 2015 | 81 | 2015 |
| Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance J Phelan, F Coll, R McNerney, DB Ascher, DEV Pires, N Furnham, ... BMC medicine 14 (1), 1-13, 2016 | 74 | 2016 |
| Studies of Glutathione Transferase P1‐1 Bound to a Platinum (IV)‐Based Anticancer Compound Reveal the Molecular Basis of Its Activation LJ Parker, LC Italiano, CJ Morton, NC Hancock, DB Ascher, JB Aitken, ... Chemistry-A European Journal 17 (28), 7806-7816, 2011 | 68 | 2011 |
| Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam KE Holt, P McAdam, PVK Thai, NTT Thuong, DTM Ha, NN Lan, NH Lan, ... Nature genetics 50 (6), 849-856, 2018 | 65 | 2018 |
| mCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistance DEV Pires, TL Blundell, DB Ascher Scientific reports 6, 29575, 2016 | 65 | 2016 |
| In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity DEV Pires, J Chen, TL Blundell, DB Ascher Scientific reports 6, 19848, 2016 | 63 | 2016 |
| Development of cognitive enhancers based on inhibition of insulin-regulated aminopeptidase SY Chai, HR Yeatman, MW Parker, DB Ascher, PE Thompson, HT Mulvey, ... BMC neuroscience 9 (S2), S14, 2008 | 63 | 2008 |
| Tumour risks and genotype–phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD KA Andrews, DB Ascher, DEV Pires, DR Barnes, L Vialard, RT Casey, ... Journal of medical genetics 55 (6), 384-394, 2018 | 62 | 2018 |
| Twelve novel HGD gene variants identified in 99 alkaptonuria patients: focus on ‘black bone disease’in Italy M Nemethova, J Radvanszky, L Kadasi, DB Ascher, DEV Pires, ... European Journal of Human Genetics 24 (1), 66-72, 2016 | 62 | 2016 |
| Platinum: a database of experimentally measured effects of mutations on structurally defined protein–ligand complexes DEV Pires, TL Blundell, DB Ascher Nucleic acids research 43 (D1), D387-D391, 2015 | 61 | 2015 |
| Optimizing genomic medicine in epilepsy through a gene-customized approach to missense variant interpretation J Traynelis, M Silk, Q Wang, SF Berkovic, L Liu, DB Ascher, DJ Balding, ... Genome research 27 (10), 1715-1729, 2017 | 60 | 2017 |
Douglas PiresSchool of Computing and Information Systems, The University of MelbourneVerified email at unimelb.edu.au
