Myriam Alcalay
Myriam Alcalay
Istituto Europeo di Oncologia, Milano / DIPO, Universita' degli Studi di Milano
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Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype
B Falini, C Mecucci, E Tiacci, M Alcalay, R Rosati, L Pasqualucci, ...
New England Journal of Medicine 352 (3), 254-266, 2005
The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells
F Grignani, PF Ferrucci, U Testa, G Talamo, M Fagioli, M Alcalay, ...
Cell 74 (3), 423-431, 1993
Acute promyelocytic leukemia: from genetics to treatment
F Grignani, M Fagioli, M Alcalay, L Longo, PP Pandolfi, E Donti, A Biondi, ...
A PMLRARα transgene initiates murine acute promyelocytic leukemia
D Brown, S Kogan, E Lagasse, I Weissman, M Alcalay, PG Pelicci, ...
Proceedings of the National Academy of Sciences 94 (6), 2551-2556, 1997
Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+ AML) shows a distinct gene expression profile characterized by up-regulation of genes …
M Alcalay, E Tiacci, R Bergomas, B Bigerna, E Venturini, SP Minardi, ...
Blood 106 (3), 899-902, 2005
Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties.
PP Pandolfi, F Grignani, M Alcalay, A Mencarelli, A Biondi, F LoCoco, ...
Oncogene 6 (7), 1285-1292, 1991
Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells
A Viale, F De Franco, A Orleth, V Cambiaghi, V Giuliani, D Bossi, ...
Nature 457 (7225), 51-56, 2009
Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus.
M Alcalay, D Zangrilli, PP Pandolfi, L Longo, A Mencarelli, ...
Proceedings of the National Academy of Sciences 88 (5), 1977-1981, 1991
Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic …
PP Pandolfi, M Alcalay, M Fagioli, D Zangrilli, A Mencarelli, D Diverio, ...
The EMBO journal 11 (4), 1397-1407, 1992
Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repair
M Alcalay, N Meani, V Gelmetti, A Fantozzi, M Fagioli, A Orleth, ...
The Journal of clinical investigation 112 (11), 1751-1761, 2003
Role for histone deacetylase 1 in human tumor cell proliferation
S Senese, K Zaragoza, S Minardi, I Muradore, S Ronzoni, A Passafaro, ...
Molecular and cellular biology 27 (13), 4784-4795, 2007
Nucleophosmin and its complex network: a possible therapeutic target in hematological diseases
E Colombo, M Alcalay, PG Pelicci
Oncogene 30 (23), 2595-2609, 2011
Rearrangements and aberrant expression of the RARα gene in acute promyelocytic leukemias
L Longo, PP Pandolfi, A Biondi, A Rambaldi, A Mencarelli, F Lo Coco, ...
Journal of Experimental Medicine 172, 1571-1575, 1990
The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein
M Alcalay, L Tomassoni, E Colombo, S Stoldt, F Grignani, M Fagioli, ...
Molecular and cellular biology 18 (2), 1084-1093, 1998
Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia
B Falini, MP Martelli, N Bolli, R Bonasso, E Ghia, MT Pallotta, D Diverio, ...
Blood 108 (6), 1999-2005, 2006
Alternative splicing of PML transcripts predicts coexpression of several carboxy-terminally different protein isoforms.
M Fagioli, M Alcalay, PP Pandolfi, L Venturini, A Mencarelli, A Simeone, ...
Oncogene 7 (6), 1083-1091, 1992
Molecular monitoring of the myl/retinoic acid receptor-alpha fusion gene in acute promyelocytic leukemia by polymerase chain reaction
A Biondi, A Rambaldi, PP Pandolfi, V Rossi, G Giudici, M Alcalay, ...
Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant
E Colombo, P Martinelli, R Zamponi, DC Shing, P Bonetti, L Luzi, ...
Cancer research 66 (6), 3044-3050, 2006
Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia.
M Alcalay, D Zangrilli, M Fagioli, PP Pandolfi, A Mencarelli, F Lo Coco, ...
Proceedings of the National Academy of Sciences 89 (11), 4840-4844, 1992
Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor
G Meroni, A Reymond, M Alcalay, G Borsani, A Tanigami, R Tonlorenzi, ...
The EMBO journal 16 (10), 2892-2906, 1997
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