| Distinct shifts in microbiota composition during Drosophila aging impair intestinal function and drive mortality RI Clark, A Salazar, R Yamada, S Fitz-Gibbon, M Morselli, J Alcaraz, ... Cell reports 12 (10), 1656-1667, 2015 | 435 | 2015 |
| Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan A Rana, M Rera, DW Walker Proceedings of the National Academy of Sciences 110 (21), 8638-8643, 2013 | 334 | 2013 |
| AMPK modulates tissue and organismal aging in a non-cell-autonomous manner M Ulgherait, A Rana, M Rera, J Graniel, DW Walker Cell reports 8 (6), 1767-1780, 2014 | 275 | 2014 |
| Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster A Rana, MP Oliveira, AV Khamoui, R Aparicio, M Rera, HB Rossiter, ... Nature communications 8 (1), 448, 2017 | 244 | 2017 |
| Pantethine rescues a Drosophila model for pantothenate kinase–associated neurodegeneration A Rana, E Seinen, K Siudeja, R Muntendam, B Srinivasan, ... Proceedings of the National Academy of Sciences 107 (15), 6988-6993, 2010 | 163 | 2010 |
| Alzheimer’s-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia BJ Andreone, L Przybyla, C Llapashtica, A Rana, SS Davis, ... Nature Neuroscience 23 (8), 927-938, 2020 | 160 | 2020 |
| Identification of the Drosophila ortholog of HSPB8: implication of HSPB8 loss of function in protein folding diseases S Carra, A Boncoraglio, B Kanon, JF Brunsting, M Minoia, A Rana, ... Journal of Biological Chemistry 285 (48), 37811-37822, 2010 | 126 | 2010 |
| De novo CoA biosynthesis is required to maintain DNA integrity during development of the Drosophila nervous system F Bosveld, A Rana, PE van der Wouden, W Lemstra, M Ritsema, ... Human molecular genetics 17 (13), 2058-2069, 2008 | 114 | 2008 |
| Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic T Logan, MJ Simon, A Rana, GM Cherf, A Srivastava, SS Davis, RLY Low, ... Cell 184 (18), 4651-4668. e25, 2021 | 112 | 2021 |
| Upregulation of the autophagy adaptor p62/SQSTM1 prolongs health and lifespan in middle-aged Drosophila R Aparicio, A Rana, DW Walker Cell reports 28 (4), 1029-1040. e5, 2019 | 102 | 2019 |
| Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated … K Siudeja, B Srinivasan, L Xu, A Rana, J De Jong, EAA Nollen, ... EMBO molecular medicine 3 (12), 755-766, 2011 | 98 | 2011 |
| Rapamycin modulates tissue aging and lifespan independently of the gut microbiota in Drosophila JM Schinaman, A Rana, WW Ja, RI Clark, DW Walker Scientific reports 9 (1), 7824, 2019 | 86 | 2019 |
| Proteasome β5 subunit overexpression improves proteostasis during aging and extends lifespan in Drosophila melanogaster NN Nguyen, A Rana, C Goldman, R Moore, J Tai, Y Hong, J Shen, ... Scientific Reports 9 (1), 3170, 2019 | 50 | 2019 |
| Stwl modifies chromatin compaction and is required to maintain DNA integrity in the presence of perturbed DNA replication X Yi, HI de Vries, K Siudeja, A Rana, W Lemstra, JF Brunsting, RM Kok, ... Molecular biology of the cell 20 (3), 983-994, 2009 | 22 | 2009 |
| Cofilin/Twinstar phosphorylation levels increase in response to impaired coenzyme a metabolism K Siudeja, NA Grzeschik, A Rana, J de Jong, OCM Sibon Public Library of Science 7 (8), e43145, 2012 | 18 | 2012 |
| Drosophila phosphopantothenoylcysteine synthetase is required for tissue morphogenesis during oogenesis F Bosveld, A Rana, W Lemstra, HH Kampinga, OCM Sibon BMC Research Notes 1, 1-10, 2008 | 15 | 2008 |
| A brain penetrant progranulin biotherapeutic rescues lysosomal and inflammatory phenotypes in the brain of GRN knockout mice: Lipids in AD and FTD: From … T Logan, S DeVos, MJ Simon, S Davis, J Wang, R Low, F Huang, ... Alzheimer's & Dementia 16, e040602, 2020 | 4 | 2020 |
| The role of impaired de novo Coenzyme A biosynthesis in pantothenate kinase-associated neurodegeneration A Rana Neurodegeneration 107 (15), 6988-93, 2010 | | 2010 |
