Pasquale Laise
Pasquale Laise
Senior Director of Single-Cell Systems Biology at DarwinHealth Inc.
Email verificata su
Citata da
Citata da
Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts
E Elyada, M Bolisetty, P Laise, WF Flynn, ET Courtois, RA Burkhart, ...
Cancer discovery 9 (8), 1102-1123, 2019
Single-cell genomics reveals a novel cell state during smooth muscle cell phenotypic switching and potential therapeutic targets for atherosclerosis in mouse and human
H Pan, C Xue, BJ Auerbach, J Fan, AC Bashore, J Cui, DY Yang, ...
Circulation 142 (21), 2060-2075, 2020
Experimental microdissection enables functional harmonisation of pancreatic cancer subtypes
C Maurer, SR Holmstrom, J He, P Laise, T Su, A Ahmed, H Hibshoosh, ...
Gut 68 (6), 1034-1043, 2019
Cell reprogramming requires silencing of a core subset of polycomb targets
G Fragola, PL Germain, P Laise, A Cuomo, A Blasimme, F Gross, ...
PLoS genetics 9 (2), e1003292, 2013
RNAontheBENCH: computational and empirical resources for benchmarking RNAseq quantification and differential expression methods
PL Germain, A Vitriolo, A Adamo, P Laise, V Das, G Testa
Nucleic acids research 44 (11), 5054-5067, 2016
The ion channels and transporters gene expression profile indicates a shift in excitability and metabolisms during malignant progression of Follicular Lymphoma
A Magi, M Masselli, C Sala, A Guerriero, P Laise, B Puccini, L Rigacci, ...
Scientific Reports 9 (1), 8586, 2019
Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network
E Signaroldi, P Laise, S Cristofanon, A Brancaccio, E Reisoli, S Atashpaz, ...
Nature communications 7 (1), 10753, 2016
A cell-of-origin epigenetic tracer reveals clinically distinct subtypes of high-grade serous ovarian cancer
P Lo Riso, CE Villa, G Gasparoni, A Vingiani, R Luongo, A Manfredi, ...
Genome Medicine 12, 1-20, 2020
Pancreatic ductal adenocarcinoma comprises coexisting regulatory states with both common and distinct dependencies
P Laise, M Turunen, HC Maurer, AG Curiel, E Elyada, B Schmierer, ...
Biorxiv, preprint, 2020
The host cell virocheckpoint: identification and pharmacologic targeting of novel mechanistic determinants of coronavirus-mediated hijacked cell states
P Laise, G Bosker, X Sun, Y Shen, EF Douglass, C Karan, RB Realubit, ...
BioRxiv, 2020
Deterministic and stochastic aspects of VEGF-A production and the cooperative behavior of tumoral cell colony
P Laise, F Di Patti, D Fanelli, M Masselli, A Arcangeli
Journal of theoretical biology 272 (1), 55-63, 2011
PISCES: A pipeline for the systematic, protein activity-based analysis of single cell RNA sequencing data
A Obradovic, L Vlahos, P Laise, J Worley, X Tan, A Wang, A Califano
Biorxiv 6, 22, 2021
Deregulation of ion channel and transporter encoding genes in pediatric gliomas
M Masselli, P Laise, G Tonini, D Fanelli, S Pillozzi, V Cetica, M Da Ros, ...
Frontiers in Oncology 2, 53, 2012
EZH2-mediated H3K27me3 targets transcriptional circuits of neuronal differentiation
S Buontempo, P Laise, JM Hughes, S Trattaro, V Das, C Rencurel, ...
Frontiers in Neuroscience 16, 814144, 2022
Modeling TGF-β signaling pathway in epithelial-mesenchymal transition
P Laise, D Fanelli, P Lió, A Arcangeli
AIP Advances 2 (1), 2012
Systematic, protein activity-based characterization of single cell State
L Vlahos, A Obradovic, J Worley, X Tan, A Howe, P Laise, A Wang, ...
bioRxiv, 2021.05. 20.445002, 2021
Single-cell based elucidation of molecularly-distinct glioblastoma states and drug sensitivity
H Ding, DM Burgenske, W Zhao, PS Subramaniam, KK Bakken, L He, ...
bioRxiv, 675439, 2019
A dynamical model of apoptosis and its role in tumor progression
P Laise, D Fanelli, A Arcangeli
Communications in Nonlinear Science and Numerical Simulation 17 (4), 1795-1804, 2012
Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis
Z Jiang, F Wu, P Laise, T Takayuki, F Na, W Kim, H Kobayashi, W Chang, ...
Cell Stem Cell 30 (8), 1091-1109. e7, 2023
A model for network-based identification and pharmacological targeting of aberrant, replication-permissive transcriptional programs induced by viral infection
P Laise, ML Stanifer, G Bosker, X Sun, S Triana, P Doldan, F La Manna, ...
Communications biology 5 (1), 714, 2022
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
Articoli 1–20