Segui
Marc A. Beal
Marc A. Beal
Head of Molecular and Applied Toxicology Section, Health Canada
Email verificata su canada.ca
Titolo
Citata da
Citata da
Anno
From sperm to offspring: Assessing the heritable genetic consequences of paternal smoking and potential public health impacts
MA Beal, CL Yauk, F Marchetti
Mutation research/Reviews in mutation research 773, 26-50, 2017
1252017
Characterizing Benzo[a]pyrene-induced lacZ mutation spectrum in transgenic mice using next-generation sequencing
MA Beal, R Gagné, A Williams, F Marchetti, CL Yauk
BMC genomics 16, 1-13, 2015
422015
Whole genome sequencing for quantifying germline mutation frequency in humans and model species: cautious optimism
MA Beal, TC Glenn, CM Somers
Mutation Research/Reviews in Mutation Research 750 (2), 96-106, 2012
312012
In Utero Exposure to Benzo[a]Pyrene Increases Mutation Burden in the Soma and Sperm of Adult Mice
MJ Meier, JM O’Brien, MA Beal, B Allan, CL Yauk, F Marchetti
Environmental Health Perspectives 125 (1), 82-88, 2017
292017
Paternal exposure to benzo (a) pyrene induces genome-wide mutations in mouse offspring
MA Beal, MJ Meier, A Williams, A Rowan-Carroll, R Gagné, SJ Lindsay, ...
Communications Biology 2 (1), 228, 2019
272019
Benzo (a) pyrene is mutagenic in mouse spermatogonial stem cells and dividing spermatogonia
JM O’Brien, MA Beal, CL Yauk, F Marchetti
Toxicological Sciences 152 (2), 363-371, 2016
222016
Transgenic rodent assay for quantifying male germ cell mutant frequency
JM O'Brien, MA Beal, JD Gingerich, L Soper, GR Douglas, CL Yauk, ...
JoVE (Journal of Visualized Experiments), e51576, 2014
222014
In silico approaches in carcinogenicity hazard assessment: current status and future needs
RR Tice, A Bassan, A Amberg, LT Anger, MA Beal, P Bellion, R Benigni, ...
Computational Toxicology 20, 100191, 2021
212021
Chemically induced mutations in a MutaMouse reporter gene inform mechanisms underlying human cancer mutational signatures
MA Beal, MJ Meier, DP LeBlanc, C Maurice, JM O’Brien, CL Yauk, ...
Communications Biology 3 (1), 438, 2020
182020
In Utero Exposure to Benzo[a]pyrene Induces Ovarian Mutations at Doses That Deplete Ovarian Follicles in Mice
U Luderer, MJ Meier, GW Lawson, MA Beal, CL Yauk, F Marchetti
Environmental and molecular mutagenesis 60 (5), 410-420, 2019
182019
Implementing in vitro bioactivity data to modernize priority setting of chemical inventories
MA Beal, M Gagne, SA Kulkarni, G Patlewicz, RS Thomas
Altex 39 (1), 123, 2022
172022
The effects of organophosphate esters used as flame retardants and plasticizers on granulosa, Leydig, and spermatogonial cells analyzed using high-content imaging
X Wang, T Luu, MA Beal, TS Barton-Maclaren, B Robaire, BF Hales
Toxicological Sciences 186 (2), 269-287, 2022
162022
Canadian regulatory perspective on next generation risk assessments for pest control products and industrial chemicals
Y Bhuller, D Ramsingh, M Beal, S Kulkarni, M Gagne, ...
Frontiers in Toxicology 3, 748406, 2021
162021
Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application
B Kuo, MA Beal, JW Wills, PA White, F Marchetti, A Nong, ...
Archives of Toxicology 96 (7), 2067-2085, 2022
142022
Elucidation of the effects of bisphenol A and structural analogs on germ and steroidogenic cells using single cell high-content imaging
A Rajkumar, T Luu, MA Beal, TS Barton-Maclaren, B Robaire, BF Hales
Toxicological Sciences 180 (2), 224-238, 2021
142021
Next generation sequencing of benzo(a)pyrene-induced lacZ mutants identifies a germ cell-specific mutation spectrum
JM O’Brien, MA Beal, CL Yauk, F Marchetti
Scientific Reports 6 (1), 36743, 2016
142016
Single-molecule PCR analysis of an unstable microsatellite for detecting mutations in sperm of mice exposed to chemical mutagens
MA Beal, A Rowan-Carroll, C Campbell, A Williams, CM Somers, ...
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 775, 26-32, 2015
142015
Phthalates and alternative plasticizers differentially affect phenotypic parameters in gonadal somatic and germ cell lines
A Rajkumar, T Luu, MA Beal, TS Barton-Maclaren, BF Hales, B Robaire
Biology of reproduction 106 (3), 613-627, 2022
132022
Characterization of unstable microsatellites in mice: No evidence for germline mutation induction following gamma‐radiation exposure
MA Beal, TC Glenn, SL Lance, CM Somers
Environmental and molecular mutagenesis 53 (8), 599-607, 2012
112012
In vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals
G Matteo, K Leingartner, A Rowan-Carroll, M Meier, A Williams, MA Beal, ...
Toxicological Sciences 191 (2), 266-275, 2023
82023
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
Articoli 1–20