Dongwon Lee
Dongwon Lee
Instructor, Boston Children's Hospital and Harvard Medical School
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Citata da
Citata da
A comparative encyclopedia of DNA elements in the mouse genome
F Yue, Y Cheng, A Breschi, J Vierstra, W Wu, T Ryba, R Sandstrom, Z Ma, ...
Nature 515 (7527), 355-364, 2014
Design of a synthetic yeast genome
SM Richardson, LA Mitchell, G Stracquadanio, K Yang, JS Dymond, ...
Science 355 (6329), 1040-1044, 2017
Enhanced regulatory sequence prediction using gapped k-mer features
M Ghandi, D Lee, M Mohammad-Noori, MA Beer
PLoS computational biology 10 (7), e1003711, 2014
A method to predict the impact of regulatory variants from DNA sequence
D Lee, DU Gorkin, M Baker, BJ Strober, AL Asoni, AS McCallion, MA Beer
Nature genetics 47 (8), 955-961, 2015
Discriminative prediction of mammalian enhancers from DNA sequence
D Lee, R Karchin, MA Beer
Genome Research, 2011
kmer-SVM: a web server for identifying predictive regulatory sequence features in genomic data sets
C Fletez-Brant, D Lee, AS McCallion, MA Beer
Nucleic acids research 41 (W1), W544-W556, 2013
gkmSVM: an R package for gapped-kmer SVM
M Ghandi, M Mohammad-Noori, N Ghareghani, D Lee, L Garraway, ...
Bioinformatics 32 (14), 2205-2207, 2016
Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis
M Pimkin, AV Kossenkov, T Mishra, CS Morrissey, W Wu, CA Keller, ...
Genome research 24 (12), 1932-1944, 2014
Enhancer Variants Synergistically Drive Dysfunction of a Gene Regulatory Network In Hirschsprung Disease
S Chatterjee, A Kapoor, JA Akiyama, DR Auer, D Lee, S Gabriel, ...
Cell 167 (2), 355-368. e10, 2016
LS-GKM: a new gkm-SVM for large-scale datasets
D Lee
Bioinformatics 32 (14), 2196-2198, 2016
Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes
DU Gorkin, D Lee, X Reed, C Fletez-Brant, SL Bessling, SK Loftus, ...
Genome Research, 2012
Rare coding variants associated with blood pressure variation in 15,914 individuals of African ancestry
P Nandakumar, LEE Dongwon, MA Richard, F Tekola-Ayele, BO Tayo, ...
Journal of hypertension 35 (7), 1381, 2017
Multiple SCN5A variant enhancers modulate its cardiac gene expression and the QT interval
A Kapoor, D Lee, L Zhu, EZ Soliman, ML Grove, E Boerwinkle, DE Arking, ...
Proceedings of the National Academy of Sciences 116 (22), 10636-10645, 2019
Human cardiac cis-regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants
D Lee, A Kapoor, A Safi, L Song, MK Halushka, GE Crawford, ...
Genome research 28 (10), 1577-1588, 2018
Cardiomyocytes have mosaic patterns of protein expression
TY Wang, D Lee, K Fox-Talbot, DE Arking, A Chakravarti, MK Halushka
Cardiovascular Pathology 34, 50-57, 2018
Methods, Systems and Devices Comprising Support Vector Machine for Regulatory Sequence Features
M Beer, D Lee
US Patent App. 14/013,920, 2014
Rare coding TTN variants are associated with electrocardiographic QT interval in the general population
A Kapoor, K Bakshy, L Xu, P Nandakumar, D Lee, E Boerwinkle, ...
Scientific reports 6 (1), 1-7, 2016
Testing the Ret and Sema3d genetic interaction in mouse enteric nervous system development
A Kapoor, DR Auer, D Lee, S Chatterjee, A Chakravarti
Human Molecular Genetics 26 (10), 1811-1820, 2017
Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome
X Jia, T Yamamura, R Gbadegesin, MT McNulty, K Song, Y Hitomi, D Lee, ...
Kidney international 98 (5), 1308-1322, 2020
Mammalian Enhancer Prediction
D Lee, MA Beer
Genome Analysis: Current Procedures and Applications, 101, 2014
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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