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Luís Fernando Saraiva Macedo Timmers
Luís Fernando Saraiva Macedo Timmers
Assistant Professor at University of Taquari Valley
Email verificata su univates.br
Titolo
Citata da
Citata da
Anno
Discovery of New Inhibitors of Mycobacterium tuberculosis InhA Enzyme Using Virtual Screening and a 3D-Pharmacophore-Based Approach
I Pauli, RN Dos Santos, DC Rostirolla, LK Martinelli, RG Ducati, ...
Journal of chemical information and modeling 53 (9), 2390-2401, 2013
942013
Geo-Measures: A PyMOL plugin for protein structure ensembles analysis
LP Kagami, GM das Neves, LFSM Timmers, RA Caceres, VL Eifler-Lima
Computational Biology and Chemistry 87, 107322, 2020
822020
Mycobacterium tuberculosis Shikimate Pathway Enzymes as Targets for the Rational Design of Anti-Tuberculosis Drugs
JES Nunes, MA Duque, TF de Freitas, L Galina, LFSM Timmers, ...
Molecules 25 (6), 1259, 2020
442020
Evaluation of molecular docking using polynomial empirical scoring functions
R Dias, LFS Macedo Timmers, RA Caceres, J de Azevedo, W Filgueira
Current drug targets 9 (12), 1062-1070, 2008
422008
Structural studies of human purine nucleoside phosphorylase: towards a new specific empirical scoring function
LFSM Timmers, RA Caceres, AL Vivan, LM Gava, R Dias, RG Ducati, ...
Archives of biochemistry and biophysics 479 (1), 28-38, 2008
422008
Molecular modeling and dynamics simulations of PNP from Streptococcus agalactiae
RA Caceres, LFS Timmers, R Dias, LA Basso, DS Santos, ...
Bioorganic & medicinal chemistry 16 (9), 4984-4993, 2008
372008
Molecular modeling as a tool for drug discovery
GB Barcellos, I Pauli, RA Caceres, LFS Macedo Timmers, R Dias, ...
Current drug targets 9 (12), 1084-1091, 2008
312008
Regioselectively controlled synthesis of 3 (5)-(trifluoromethyl) pyrazolylbenzenesulfonamides and their effects on a pathological pain model in mice
MM Lobo, SM Oliveira, I Brusco, P Machado, LFSM Timmers, ...
European journal of medicinal chemistry 102, 143-152, 2015
292015
Activity of 2-(quinolin-4-yloxy) acetamides in Mycobacterium tuberculosis clinical isolates and identification of their molecular target by whole-genome sequencing
FT Subtil, AD Villela, BL Abbadi, VS Rodrigues-Junior, CV Bizarro, ...
International Journal of Antimicrobial Agents 51 (3), 378-384, 2018
272018
In silico and in vitro: identifying new drugs
I Pauli, LFS Macedo Timmers, RA Caceres, MB Pereira Soares, ...
Current drug targets 9 (12), 1054-1061, 2008
272008
Drug-binding databases
LFS Macedo Timmers, I Pauli, RA Caceres, J de Azevedo, W Filgueira
Current drug targets 9 (12), 1092-1099, 2008
262008
Piperazine derivatives: Synthesis, inhibition of the Mycobacterium tuberculosis enoyl-acyl carrier protein reductase and SAR studies
M Rotta, K Pissinate, AD Villela, DF Back, LFSM Timmers, JFR Bachega, ...
European Journal of Medicinal Chemistry 90, 436-447, 2015
242015
Design of novel potent inhibitors of human uridine phosphorylase-1: synthesis, inhibition studies, thermodynamics, and in vitro influence on 5-fluorouracil cytotoxicity
D Renck, P Machado, AA Souto, LA Rosado, T Erig, MM Campos, ...
Journal of medicinal chemistry 56 (21), 8892-8902, 2013
242013
Alkaloid profile and cholinesterase inhibition activity of five species of Amaryllidaceae family collected from Mérida state-Venezuela
JDC Rojas-Vera, AA Buitrago-Díaz, LM Possamai, LFSM Timmers, ...
South African journal of botany 136, 126-136, 2021
232021
Crystal structure and molecular dynamics studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis associated with acyclovir
RA Caceres, LFSM Timmers, RG Ducati, DON Da Silva, LA Basso, ...
Biochimie 94 (1), 155-165, 2012
222012
SARS-CoV-2 mutations in Brazil: from genomics to putative clinical conditions
LFSM Timmers, JV Peixoto, RG Ducati, JFR Bachega, L de Mattos Pereira, ...
Scientific reports 11 (1), 11998, 2021
212021
GTKDynamo: A PyMOL plug‐in for QC/MM hybrid potential simulations
JFR Bachega, LFSM Timmers, L Assirati, LR Bachega, MJ Field, ...
Journal of computational chemistry 34 (25), 2190-2196, 2013
202013
Review of trials currently testing stem cells for treatment of respiratory diseases: facts known to date and possible applications to COVID-19
F Majolo, GL da Silva, L Vieira, LFSM Timmers, S Laufer, MI Goettert
Stem cell reviews and reports 17, 44-55, 2021
182021
Searching for potential mTOR inhibitors: Ligand-based drug design, docking and molecular dynamics studies of rapamycin binding site
R Kist, LFSM Timmers, RA Caceres
Journal of Molecular Graphics and Modelling 80, 251-263, 2018
182018
Pre-clinical evaluation of quinoxaline-derived chalcones in tuberculosis
TC Muradás, BL Abbadi, AD Villela, FS Macchi, PF Bergo, TF de Freitas, ...
PLoS One 13 (8), e0202568, 2018
172018
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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