| A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia–reperfusion in the mouse C Marchetti, J Chojnacki, S Toldo, E Mezzaroma, N Tranchida, SW Rose, ... Journal of cardiovascular pharmacology 63 (4), 316-322, 2014 | 262 | 2014 |
| Inhibition of the NLRP3 inflammasome limits the inflammatory injury following myocardial ischemia–reperfusion in the mouse S Toldo, C Marchetti, AG Mauro, J Chojnacki, E Mezzaroma, S Carbone, ... International Journal of Cardiology 209, 215-220, 2016 | 199 | 2016 |
| NLRP3 inflammasome inhibitor ameliorates amyloid pathology in a mouse model of Alzheimer’s disease J Yin, F Zhao, JE Chojnacki, J Fulp, WL Klein, S Zhang, X Zhu Molecular neurobiology 55, 1977-1987, 2018 | 198 | 2018 |
| Natural product-based amyloid inhibitors P Velander, L Wu, F Henderson, S Zhang, DR Bevan, B Xu Biochemical pharmacology 139, 40-55, 2017 | 192 | 2017 |
| Pharmacologic inhibition of the NLRP3 inflammasome preserves cardiac function after ischemic and nonischemic injury in the mouse C Marchetti, S Toldo, J Chojnacki, E Mezzaroma, K Liu, FN Salloum, ... Journal of cardiovascular pharmacology 66 (1), 1-8, 2015 | 158 | 2015 |
| A novel small molecular NLRP3 inflammasome inhibitor alleviates neuroinflammatory response following traumatic brain injury R Kuwar, A Rolfe, L Di, H Xu, L He, Y Jiang, S Zhang, D Sun Journal of neuroinflammation 16, 1-14, 2019 | 145 | 2019 |
| The NLRP3 inflammasome pathway: A review of mechanisms and inhibitors for the treatment of inflammatory diseases HM Blevins, Y Xu, S Biby, S Zhang Frontiers in aging neuroscience 14, 879021, 2022 | 123 | 2022 |
| Structural insights of benzenesulfonamide analogues as NLRP3 inflammasome inhibitors: design, synthesis, and biological characterization J Fulp, L He, S Toldo, Y Jiang, A Boice, C Guo, X Li, A Rolfe, D Sun, ... Journal of medicinal chemistry 61 (12), 5412-5423, 2018 | 96 | 2018 |
| Discovery of 5-(4-hydroxyphenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide as a neuroprotectant for Alzheimer’s disease by hybridization of curcumin and … JE Chojnacki, K Liu, X Yan, S Toldo, T Selden, M Estrada, ... ACS chemical neuroscience 5 (8), 690-699, 2014 | 88 | 2014 |
| Development and Characterization of a Hydroxyl-Sulfonamide Analogue, 5-Chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxy-benzamide, as a Novel … C Guo, JW Fulp, Y Jiang, X Li, JE Chojnacki, J Wu, XY Wang, S Zhang ACS chemical neuroscience 8 (10), 2194-2201, 2017 | 83 | 2017 |
| Curcumin/Melatonin Hybrid 5-(4-Hydroxy-phenyl)-3-oxo-pentanoic Acid [2-(5-Methoxy-1H-indol-3-yl)-ethyl]-amide Ameliorates AD-Like Pathology in the APP/PS1 … G Gerenu, K Liu, JE Chojnacki, JM Saathoff, P Martínez-Martín, G Perry, ... ACS chemical neuroscience 6 (8), 1393-1399, 2015 | 65 | 2015 |
| A novel inhibitor targeting NLRP3 inflammasome reduces neuropathology and improves cognitive function in Alzheimer’s disease transgenic mice R Kuwar, A Rolfe, L Di, H Blevins, Y Xu, X Sun, GS Bloom, S Zhang, ... Journal of Alzheimer's Disease 82 (4), 1769-1783, 2021 | 44 | 2021 |
| Discovery of second-generation NLRP3 inflammasome inhibitors: Design, synthesis, and biological characterization Y Jiang, L He, J Green, H Blevins, C Guo, SH Patel, MS Halquist, ... Journal of medicinal chemistry 62 (21), 9718-9731, 2019 | 40 | 2019 |
| Bivalent ligands incorporating curcumin and diosgenin as multifunctional compounds against Alzheimer’s disease JE Chojnacki, K Liu, JM Saathoff, S Zhang Bioorganic & Medicinal Chemistry 23 (22), 7324-7331, 2015 | 35 | 2015 |
| Identification of metabolite biomarkers of the designer hallucinogen 25I-NBOMe in mouse hepatic microsomal preparations and human urine samples associated with clinical … JL Poklis, SK Dempsey, K Liu, JK Ritter, C Wolf, S Zhang, A Poklis Journal of analytical toxicology 39 (8), 607-616, 2015 | 34 | 2015 |
| Sinapine thiocyanate ameliorates vascular endothelial dysfunction in hypertension by inhibiting activation of the NLRP3 inflammasome Y Liu, H Yin, C Li, F Jiang, S Zhang, X Zhang, Y Li Frontiers in Pharmacology 11, 620159, 2021 | 29 | 2021 |
| Highly efficient synthesis of 1, 3-dihydroxy-2-carboxycarbazole and Its neuroprotective effects K Liu, S Zhang ACS Medicinal Chemistry Letters 6 (8), 894-897, 2015 | 19 | 2015 |
| Analysis of the First‐and Second‐Generation Raving Dragon Novelty Bath Salts Containing Methylone and Pentedrone JL Poklis, CE Wolf, OI ElJordi, K Liu, S Zhang, A Poklis Journal of Forensic Sciences 60, S234-S240, 2015 | 17 | 2015 |
| A comparison of the location in membranes of curcumin and curcumin-derived bivalent compounds with potential neuroprotective capacity for Alzheimer’s disease A Ausili, V Gómez-Murcia, AM Candel, A Beltrán, A Torrecillas, L He, ... Colloids and Surfaces B: Biointerfaces 199, 111525, 2021 | 16 | 2021 |
| Insights into the impact of a membrane-anchoring moiety on the biological activities of bivalent compounds as potential neuroprotectants for Alzheimer’s disease L He, Y Jiang, K Liu, V Gomez-Murcia, X Ma, A Torrecillas, Q Chen, X Zhu, ... Journal of medicinal chemistry 61 (3), 777-790, 2018 | 15 | 2018 |
