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Arkady Khoutorsky
Arkady Khoutorsky
Email verificata su mcgill.ca
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Citata da
Citata da
Anno
Pharmacological brake-release of mRNA translation enhances cognitive memory
C Sidrauski, D Acosta-Alvear, A Khoutorsky, P Vedantham, BR Hearn, ...
elife 2, e00498, 2013
6282013
Autism-related deficits via dysregulated eIF4E-dependent translational control
CG Gkogkas, A Khoutorsky, I Ran, E Rampakakis, T Nevarko, ...
Nature 493 (7432), 371-377, 2013
5612013
Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain
OK Melemedjian, MN Asiedu, DV Tillu, R Sanoja, J Yan, A Lark, ...
Molecular pain 7, 1744-8069-7-70, 2011
2242011
Translation deregulation in human disease
S Tahmasebi, A Khoutorsky, MB Mathews, N Sonenberg
Nature reviews Molecular cell biology 19 (12), 791-807, 2018
2112018
Metformin ameliorates core deficits in a mouse model of fragile X syndrome
I Gantois, A Khoutorsky, J Popic, A Aguilar-Valles, E Freemantle, R Cao, ...
Nature medicine 23 (6), 674-677, 2017
1962017
Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes
CG Gkogkas, A Khoutorsky, R Cao, SM Jafarnejad, M Prager-Khoutorsky, ...
Cell reports 9 (5), 1742-1755, 2014
1952014
Reactivation of stalled polyribosomes in synaptic plasticity
TE Graber, S Hébert-Seropian, A Khoutorsky, A David, JW Yewdell, ...
Proceedings of the National Academy of Sciences 110 (40), 16205-16210, 2013
1782013
Translational control of entrainment and synchrony of the suprachiasmatic circadian clock by mTOR/4E-BP1 signaling
R Cao, B Robinson, H Xu, C Gkogkas, A Khoutorsky, T Alain, A Yanagiya, ...
Neuron 79 (4), 712-724, 2013
1572013
Molecular and genetic crosstalks between mTOR and ERRα are key determinants of rapamycin-induced nonalcoholic fatty liver
C Chaveroux, LJ Eichner, CR Dufour, A Shatnawi, A Khoutorsky, ...
Cell metabolism 17 (4), 586-598, 2013
1552013
The MNK–eIF4E signaling axis contributes to injury-induced nociceptive plasticity and the development of chronic pain
JK Moy, A Khoutorsky, MN Asiedu, BJ Black, JL Kuhn, ...
Journal of Neuroscience 37 (31), 7481-7499, 2017
1272017
Unique interweaved microtubule scaffold mediates osmosensory transduction via physical interaction with TRPV1
M Prager-Khoutorsky, A Khoutorsky, CW Bourque
Neuron 83 (4), 866-878, 2014
1202014
Translational control mechanisms in persistent pain
A Khoutorsky, TJ Price
Trends in neurosciences 41 (2), 100-114, 2018
1092018
Nociceptor translational profiling reveals the Ragulator-Rag GTPase complex as a critical generator of neuropathic pain
S Megat, PR Ray, JK Moy, TF Lou, P Barragán-Iglesias, Y Li, G Pradhan, ...
Journal of Neuroscience 39 (3), 393-411, 2019
1032019
mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK
OK Melemedjian, A Khoutorsky, RE Sorge, J Yan, MN Asiedu, A Valdez, ...
PAIN® 154 (7), 1080-1091, 2013
1002013
Epiregulin and EGFR interactions are involved in pain processing
LJ Martin, SB Smith, A Khoutorsky, CA Magnussen, A Samoshkin, ...
The Journal of clinical investigation 127 (9), 3353-3366, 2017
982017
eIF2α controls memory consolidation via excitatory and somatostatin neurons
V Sharma, R Sood, A Khlaifia, MJ Eslamizade, TY Hung, D Lou, ...
Nature 586 (7829), 412-416, 2020
862020
Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2
S Tahmasebi, SM Jafarnejad, IS Tam, T Gonatopoulos-Pournatzis, ...
Proceedings of the National Academy of Sciences 113 (44), 12360-12367, 2016
772016
Control of synaptic plasticity and memory via suppression of poly (A)-binding protein
A Khoutorsky, A Yanagiya, CG Gkogkas, MR Fabian, ...
Neuron 78 (2), 298-311, 2013
772013
Single-cell RNA sequencing reveals time-and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain
S Tansley, S Uttam, A Ureña Guzmán, M Yaqubi, A Pacis, M Parisien, ...
Nature communications 13 (1), 843, 2022
702022
Metformin for treatment of fragile X syndrome and other neurological disorders
I Gantois, J Popic, A Khoutorsky, N Sonenberg
Annual review of medicine 70, 167-181, 2019
702019
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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