| Dynamic balance of pro‐and anti‐inflammatory signals controls disease and limits pathology JM Cicchese, S Evans, C Hult, LR Joslyn, T Wessler, JA Millar, S Marino, ... Immunological reviews 285 (1), 147-167, 2018 | 218 | 2018 |
| Overcoming anti-PEG antibody mediated accelerated blood clearance of PEGylated liposomes by pre-infusion with high molecular weight free PEG MD McSweeney, LSL Price, T Wessler, EC Ciociola, LB Herity, ... Journal of controlled release 311, 138-146, 2019 | 63 | 2019 |
| A minimal physiologically based pharmacokinetic model that predicts anti-PEG IgG-mediated clearance of PEGylated drugs in human and mouse MD McSweeney, T Wessler, LSL Price, EC Ciociola, LB Herity, ... Journal of Controlled Release 284, 171-178, 2018 | 57 | 2018 |
| A blueprint for robust crosslinking of mobile species in biogels with weakly adhesive molecular anchors J Newby, JL Schiller, T Wessler, J Edelstein, MG Forest, SK Lai Nature communications 8 (1), 833, 2017 | 40 | 2017 |
| Using computational modeling to optimize the design of antibodies that trap viruses in mucus T Wessler, A Chen, SA McKinley, R Cone, MG Forest, SK Lai ACS infectious diseases 2 (1), 82-92, 2016 | 38 | 2016 |
| Modeling the excess cell surface stored in a complex morphology of bleb-like protrusions M Kapustina, D Tsygankov, J Zhao, T Wessler, X Yang, A Chen, N Roach, ... PLoS computational biology 12 (3), e1004841, 2016 | 35 | 2016 |
| A computational model tracks whole-lung Mycobacterium tuberculosis infection and predicts factors that inhibit dissemination T Wessler, LR Joslyn, HJ Borish, HP Gideon, JAL Flynn, DE Kirschner, ... PLoS computational biology 16 (5), e1007280, 2020 | 25 | 2020 |
| Modeling barrier properties of intestinal mucus reinforced with IgG and secretory IgA against motile bacteria F Xu, JM Newby, JL Schiller, HA Schroeder, T Wessler, A Chen, ... ACS infectious diseases 5 (9), 1570-1580, 2019 | 25 | 2019 |
| An agent-based systems pharmacology model of the antibody-drug conjugate kadcyla to predict efficacy of different dosing regimens B Menezes, C Cilliers, T Wessler, GM Thurber, JJ Linderman The AAPS journal 22, 1-13, 2020 | 24 | 2020 |
| Modeling insights into SARS-CoV-2 respiratory tract infections prior to immune protection A Chen, T Wessler, K Daftari, K Hinton, RC Boucher, R Pickles, ... Biophysical Journal 121 (9), 1619-1631, 2022 | 21 | 2022 |
| Data-driven model validation across dimensions M Renardy, T Wessler, S Blemker, J Linderman, S Peirce, D Kirschner Bulletin of mathematical biology 81, 1853-1866, 2019 | 8 | 2019 |
| Modeling identifies variability in SARS-CoV-2 uptake and eclipse phase by infected cells as principal drivers of extreme variability in nasal viral load in the 48 h post infection J Pearson, T Wessler, A Chen, RC Boucher, R Freeman, SK Lai, ... Journal of Theoretical biology 565, 111470, 2023 | 7 | 2023 |
| Antibody protection from SARS-CoV-2 respiratory tract exposure and infection A Chen, T Wessler, MG Forest Journal of Theoretical Biology 557, 111334, 2023 | 7 | 2023 |
| Optimized crosslinkers for trapping a target on a substrate S Lai, MG Forest, C Henry, T Wessler, A Chen, J Schiller, J Newby US Patent 10,793,623, 2020 | 6 | 2020 |
| A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes AM Talkington, MD McSweeney, T Wessler, MK Rath, Z Li, T Zhang, ... Journal of Controlled Release 343, 518-527, 2022 | 5 | 2022 |
| Experimental data and PBPK modeling quantify antibody interference in PEGylated drug carrier delivery AM Talkington, T Wessler, SK Lai, Y Cao, MG Forest Bulletin of Mathematical Biology 83 (12), 123, 2021 | 4 | 2021 |
| Modeling predicts mechanisms altered by mutations of the SARS-CoV-2 delta and omicron variants J Pearson, T Wessler, A Chen, RC Boucher, R Freeman, SK Lai, ... bioRxiv, 2022.02. 23.481492, 2022 | 3 | 2022 |
| Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration AM Travis, S Manocha, JR Willer, TS Wessler, NP Skiba, JN Pearring Elife 12, e80533, 2023 | 2 | 2023 |
| Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration AM Travis, S Manocha, JR Willer, TS Wessler, NP Skiba, JN Pearring bioRxiv, 2022.05. 02.490367, 2022 | 1 | 2022 |
| Computational Modeling Insights into Extreme Heterogeneity in COVID-19 Nasal Swab Data L Zhang, H Cao, K Medlin, J Pearson, AC Aristotelous, A Chen, T Wessler, ... Viruses 16 (1), 69, 2023 | | 2023 |
