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John Welsh
John Welsh
Principal Consultant, Rivanna Bioprocess Solutions LLC
Verified email at rivannabioprocess.com
Title
Cited by
Cited by
Year
Production and stabilization of the trimeric influenza hemagglutinin stem domain for potentially broadly protective influenza vaccines
Y Lu, JP Welsh, JR Swartz
Proceedings of the National Academy of Sciences 111 (1), 125-130, 2014
2442014
Predicting Antibody Developability Profiles Through Early Stage Discovery Screening
M Bailly, C Mieczkowski, V Juan, E Metwally, D Tomazela, J Baker, ...
Mabs 12 (1), 1743053, 2020
1452020
Multiply mutated Gaussia luciferases provide prolonged and intense bioluminescence
JP Welsh, KG Patel, K Manthiram, JR Swartz
Biochemical and biophysical research communications 389 (4), 563-568, 2009
1032009
A practical strategy for using miniature chromatography columns in a standardized high‐throughput workflow for purification development of monoclonal antibodies
JP Welsh, MG Petroff, P Rowicki, H Bao, T Linden, DJ Roush, JM Pollard
Biotechnology progress 30 (3), 626-635, 2014
672014
Escherichia coli‐based cell free production of flagellin and ordered flagellin display on virus‐like particles
Y Lu, JP Welsh, W Chan, JR Swartz
Biotechnology and bioengineering 110 (8), 2073-2085, 2013
622013
Cell‐free production of trimeric influenza hemagglutinin head domain proteins as vaccine antigens
JP Welsh, Y Lu, XS He, HB Greenberg, JR Swartz
Biotechnology and bioengineering 109 (12), 2962-2969, 2012
442012
Prediction of lab and manufacturing scale chromatography performance using mini-columns and mechanistic modeling
SW Benner, JP Welsh, MA Rauscher, JM Pollard
Journal of Chromatography A 1593, 54-62, 2019
402019
Comparing the functional properties of the Hsp70 chaperones, DnaK and BiP
J Bonomo, JP Welsh, K Manthiram, JR Swartz
Biophysical chemistry 149 (1-2), 58-66, 2010
332010
Toward in silico CMC: An industrial collaborative approach to model‐based process development
D Roush, D Asthagiri, DK Babi, S Benner, C Bilodeau, G Carta, P Ernst, ...
Biotechnology and Bioengineering 117 (12), 3986-4000, 2020
302020
High throughput chromatography strategies for potential use in the formal process characterization of a monoclonal antibody
MG Petroff, H Bao, JP Welsh, M van Beuningen–de Vaan, JM Pollard, ...
Biotechnology and bioengineering 113 (6), 1273-1283, 2016
232016
Localization of BiP to translating ribosomes increases soluble accumulation of secreted eukaryotic proteins in an Escherichia coli cell‐free system
JP Welsh, J Bonomo, JR Swartz
Biotechnology and bioengineering 108 (8), 1739-1748, 2011
202011
Opportunities and challenges for model utilization in the biopharmaceutical industry: current versus future state
DK Babi, J Griesbach, S Hunt, F Insaidoo, D Roush, R Todd, A Staby, ...
Current Opinion in Chemical Engineering 36, 100813, 2022
192022
High‐throughput techniques to evaluate the effect of ligand density for impurity separations with multimodal cation exchange resins
JP Welsh, H Bao, K Barlow, JM Pollard, E Brekkan, KM Lacki, TO Linden, ...
Engineering in Life Sciences 16 (2), 160-168, 2016
132016
Domain antibody downstream process optimization: High‐throughput strategy and analytical methods
JP Welsh, MA Rauscher, H Bao, S Meissner, IK Han, TO Linden, ...
Engineering in Life Sciences 16 (2), 133-142, 2016
122016
Highland Games: A benchmarking exercise in predicting biophysical and drug properties of monoclonal antibodies from amino acid sequences
J Coffman, B Marques, R Orozco, M Aswath, H Mohammad, ...
Biotechnology and Bioengineering 117 (7), 2100-2115, 2020
102020
Solubility partner IF2 Domain I enables high yield synthesis of transducible transcription factors in Escherichia coli
WC Yang, JP Welsh, J Lee, JP Cooke, JR Swartz
Protein expression and purification 80 (1), 145-151, 2011
102011
Application of simplex‐based experimental optimization to challenging bioprocess development problems: Case studies in downstream processing
S Konstantinidis, JP Welsh, DJ Roush, A Velayudhan
Biotechnology progress 32 (2), 404-419, 2016
92016
Pushing the limits of high-throughput chromatography process development: current state and future directions
J Welsh
Pharmaceutical Bioprocessing 3 (1), 1-3, 2015
92015
Demonstrating β-glucan clearance in CHO-and yeast-produced monoclonal antibodies during downstream purification processes
F Wang, H Li, Z Chen, JP Welsh, D Richardson, JM Pollard, D Richardson, ...
J Bioprocess Biotech 4 (185), 2, 2014
92014
Isotherm model discrimination for multimodal chromatography using mechanistic models derived from high-throughput batch isotherm data
SH Altern, JP Welsh, JY Lyall, AJ Kocot, S Burgess, V Kumar, C Williams, ...
Journal of Chromatography A 1693, 463878, 2023
72023
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