| Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis DR Booth, M Sunde, V Bellotti, CV Robinson, WL Hutchinson, PE Fraser, ... Nature 385 (6619), 787, 1997 | 1161 | 1997 |
| Responsive gels formed by the spontaneous self-assembly of peptides into polymeric β-sheet tapes A Aggeli, M Bell, N Boden, JN Keen, PF Knowles, TCB McLeish, ... Nature 386 (6622), 259, 1997 | 883 | 1997 |
| The folding of hen lysozyme involves partially structured intermediates and multiple pathways SE Radford, CM Dobson, PA Evans Nature 358 (6384), 302, 1992 | 818 | 1992 |
| Nucleation of protein fibrillation by nanoparticles S Linse, C Cabaleiro-Lago, WF Xue, I Lynch, S Lindman, E Thulin, ... Proceedings of the National Academy of Sciences 104 (21), 8691-8696, 2007 | 753 | 2007 |
| Detection of transient protein folding populations by mass spectrometry A Miranker, CV Robinson, SE Radford, RT Aplin, CM Dobson Science 262 (5135), 896-900, 1993 | 652 | 1993 |
| pH as a trigger of peptide β-sheet self-assembly and reversible switching between nematic and isotropic phases A Aggeli, M Bell, LM Carrick, CWG Fishwick, R Harding, PJ Mawer, ... Journal of the American Chemical Society 125 (32), 9619-9628, 2003 | 443 | 2003 |
| Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly WF Xue, SW Homans, SE Radford Proceedings of the National Academy of Sciences 105 (26), 8926-8931, 2008 | 401 | 2008 |
| Understanding how proteins fold: the lysozyme story so far CM Dobson, PA Evans, SE Radford Trends in biochemical sciences 19 (1), 31-37, 1994 | 388 | 1994 |
| Pulling geometry defines the mechanical resistance of a β-sheet protein DJ Brockwell, E Paci, RC Zinober, GS Beddard, PD Olmsted, DA Smith, ... Nature Structural & Molecular Biology 10 (9), 731, 2003 | 370 | 2003 |
| The Yin and Yang of protein folding TR Jahn, SE Radford The FEBS journal 272 (23), 5962-5970, 2005 | 360 | 2005 |
| Competing pathways determine fibril morphology in the self-assembly of β2-microglobulin into amyloid WS Gosal, IJ Morten, EW Hewitt, DA Smith, NH Thomson, SE Radford Journal of molecular biology 351 (4), 850-864, 2005 | 358 | 2005 |
| Partially Unfolded States of β2-Microglobulin and Amyloid Formation in Vitro VJ McParland, NM Kad, AP Kalverda, A Brown, P Kirwin-Jones, ... Biochemistry 39 (30), 8735-8746, 2000 | 353 | 2000 |
| Folding versus aggregation: polypeptide conformations on competing pathways TR Jahn, SE Radford Archives of biochemistry and biophysics 469 (1), 100-117, 2008 | 347 | 2008 |
| Deciphering drift time measurements from travelling wave ion mobility spectrometry-mass spectrometry studies DP Smith, TW Knapman, I Campuzano, RW Malham, JT Berryman, ... European journal of mass spectrometry 15 (2), 113-130, 2009 | 323 | 2009 |
| A partially folded state of hen egg white lysozyme in trifluoroethanol: structural characterization and implications for protein folding M Buck, SE Radford, CM Dobson Biochemistry 32 (2), 669-678, 1993 | 308 | 1993 |
| Fibril fragmentation enhances amyloid cytotoxicity WF Xue, AL Hellewell, WS Gosal, SW Homans, EW Hewitt, SE Radford Journal of Biological Chemistry 284 (49), 34272-34282, 2009 | 302 | 2009 |
| Amyloid formation under physiological conditions proceeds via a native-like folding intermediate TR Jahn, MJ Parker, SW Homans, SE Radford Nature structural & molecular biology 13 (3), 195, 2006 | 297 | 2006 |
| Im7 folding mechanism: misfolding on a path to the native state AP Capaldi, C Kleanthous, SE Radford Nature Structural & Molecular Biology 9 (3), 209, 2002 | 290 | 2002 |
| Rapid folding with and without populated intermediates in the homologous four-helix proteins Im7 and Im9 N Ferguson, AP Capaldi, R James, C Kleanthous, SE Radford Journal of molecular biology 286 (5), 1597-1608, 1999 | 262 | 1999 |
| Demonstration by NMR of folding domains in lysozyme A Miranker, SE Radford, M Karplus, CM Dobson Nature 349 (6310), 633, 1991 | 260 | 1991 |
Christopher DobsonUniversity of CambridgeVerified email at cam.ac.uk
