Menghang Xia
Menghang Xia
National Center for Advancing Transnational Sciences, NIH
Email verificata su mail.nih.gov
Titolo
Citata da
Citata da
Anno
High-throughput screening assays for the identification of chemical probes
J Inglese, RL Johnson, A Simeonov, M Xia, W Zheng, CP Austin, DS Auld
Nature chemical biology 3 (8), 466-479, 2007
6462007
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
M Xu, EM Lee, Z Wen, Y Cheng, WK Huang, X Qian, TCW Julia, ...
Nature medicine 22 (10), 1101-1107, 2016
5092016
Compound cytotoxicity profiling using quantitative high-throughput screening
M Xia, R Huang, KL Witt, N Southall, J Fostel, MH Cho, A Jadhav, ...
Environmental health perspectives 116 (3), 284-291, 2008
2642008
Identification of known drugs that act as inhibitors of NF-κB signaling and their mechanism of action
SC Miller, R Huang, S Sakamuru, SJ Shukla, MS Attene-Ramos, P Shinn, ...
Biochemical pharmacology 79 (9), 1272-1280, 2010
2562010
The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform
SJ Shukla, R Huang, CP Austin, M Xia
Drug discovery today 15 (23-24), 997-1007, 2010
2442010
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ...
Carcinogenesis 36 (Suppl_1), S254-S296, 2015
2392015
5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary
T Khare, S Pai, K Koncevicius, M Pal, E Kriukiene, Z Liutkeviciute, M Irimia, ...
Nature structural & molecular biology 19 (10), 1037-1043, 2012
2392012
Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors
A Singh, S Venkannagari, KH Oh, YQ Zhang, JM Rohde, L Liu, ...
ACS chemical biology 11 (11), 3214-3225, 2016
2192016
Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor
RS Judson, FM Magpantay, V Chickarmane, C Haskell, N Tania, J Taylor, ...
Toxicological Sciences 148 (1), 137-154, 2015
2092015
Stimulus specificity of matrix metalloproteinase dependence of human T cell migration through a model basement membrane.
M Xia, D Leppert, SL Hauser, SP Sreedharan, PJ Nelson, AM Krensky, ...
The Journal of Immunology 156 (1), 160-167, 1996
2011996
Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity
RS Judson, MT Martin, DM Reif, KA Houck, TB Knudsen, DM Rotroff, ...
Environmental science & technology 44 (15), 5979-5985, 2010
1932010
Assay guidance manual [Internet]
GS Sittampalam, A Grossman, K Brimacombe, M Arkin, D Auld, CP Austin, ...
Eli Lilly & Company and the National Center for Advancing Translational Sciences, 2004
1852004
Cloning and expression of the EP2 subtype of human receptors for prostaglandin E2
SZ An, JH Yang, MH Xia, EJ Goetzl
Biochemical and biophysical research communications 197 (1), 263-270, 1993
1841993
Chemical genomics profiling of environmental chemical modulation of human nuclear receptors
R Huang, M Xia, MH Cho, S Sakamuru, P Shinn, KA Houck, DJ Dix, ...
Environmental health perspectives 119 (8), 1142-1148, 2011
1702011
The Tox21 robotic platform for the assessment of environmental chemicals–from vision to reality
MS Attene-Ramos, N Miller, R Huang, S Michael, M Itkin, RJ Kavlock, ...
Drug discovery today 18 (15-16), 716-723, 2013
1652013
Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space
R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ...
Toxicological Sciences 152 (2), 323-339, 2016
1632016
Bisphenol A affects androgen receptor function via multiple mechanisms
C Teng, B Goodwin, K Shockley, M Xia, R Huang, J Norris, BA Merrick, ...
Chemico-biological interactions 203 (3), 556-564, 2013
1522013
Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals
ATJ Murk, E Rijntjes, BJ Blaauboer, R Clewell, KM Crofton, ...
Toxicology in vitro 27 (4), 1320-1346, 2013
1502013
Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization
R Huang, M Xia, S Sakamuru, J Zhao, SA Shahane, M Attene-Ramos, ...
Nature communications 7 (1), 1-10, 2016
1412016
Molecular signatures associated with ZIKV exposure in human cortical neural progenitors
F Zhang, C Hammack, SC Ogden, Y Cheng, EM Lee, Z Wen, X Qian, ...
Nucleic acids research 44 (18), 8610-8620, 2016
1372016
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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