Menghang Xia
Menghang Xia
National Center for Advancing Transnational Sciences, NIH
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High-throughput screening assays for the identification of chemical probes
J Inglese, RL Johnson, A Simeonov, M Xia, W Zheng, CP Austin, DS Auld
Nature chemical biology 3 (8), 466-479, 2007
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
M Xu, EM Lee, Z Wen, Y Cheng, WK Huang, X Qian, TCW Julia, ...
Nature medicine 22 (10), 1101-1107, 2016
Compound cytotoxicity profiling using quantitative high-throughput screening
M Xia, R Huang, KL Witt, N Southall, J Fostel, MH Cho, A Jadhav, ...
Environmental health perspectives 116 (3), 284-291, 2008
Identification of known drugs that act as inhibitors of NF-κB signaling and their mechanism of action
SC Miller, R Huang, S Sakamuru, SJ Shukla, MS Attene-Ramos, P Shinn, ...
Biochemical pharmacology 79 (9), 1272-1280, 2010
The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform
SJ Shukla, R Huang, CP Austin, M Xia
Drug discovery today 15 (23-24), 997-1007, 2010
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ...
Carcinogenesis 36 (Suppl_1), S254-S296, 2015
5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary
T Khare, S Pai, K Koncevicius, M Pal, E Kriukiene, Z Liutkeviciute, M Irimia, ...
Nature structural & molecular biology 19 (10), 1037-1043, 2012
Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors
A Singh, S Venkannagari, KH Oh, YQ Zhang, JM Rohde, L Liu, ...
ACS chemical biology 11 (11), 3214-3225, 2016
Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor
RS Judson, FM Magpantay, V Chickarmane, C Haskell, N Tania, J Taylor, ...
Toxicological Sciences 148 (1), 137-154, 2015
Stimulus specificity of matrix metalloproteinase dependence of human T cell migration through a model basement membrane.
M Xia, D Leppert, SL Hauser, SP Sreedharan, PJ Nelson, AM Krensky, ...
The Journal of Immunology 156 (1), 160-167, 1996
Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity
RS Judson, MT Martin, DM Reif, KA Houck, TB Knudsen, DM Rotroff, ...
Environmental science & technology 44 (15), 5979-5985, 2010
Assay guidance manual [Internet]
GS Sittampalam, A Grossman, K Brimacombe, M Arkin, D Auld, CP Austin, ...
Eli Lilly & Company and the National Center for Advancing Translational Sciences, 2004
Cloning and expression of the EP2 subtype of human receptors for prostaglandin E2
SZ An, JH Yang, MH Xia, EJ Goetzl
Biochemical and biophysical research communications 197 (1), 263-270, 1993
Chemical genomics profiling of environmental chemical modulation of human nuclear receptors
R Huang, M Xia, MH Cho, S Sakamuru, P Shinn, KA Houck, DJ Dix, ...
Environmental health perspectives 119 (8), 1142-1148, 2011
The Tox21 robotic platform for the assessment of environmental chemicals–from vision to reality
MS Attene-Ramos, N Miller, R Huang, S Michael, M Itkin, RJ Kavlock, ...
Drug discovery today 18 (15-16), 716-723, 2013
Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space
R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ...
Toxicological Sciences 152 (2), 323-339, 2016
Bisphenol A affects androgen receptor function via multiple mechanisms
C Teng, B Goodwin, K Shockley, M Xia, R Huang, J Norris, BA Merrick, ...
Chemico-biological interactions 203 (3), 556-564, 2013
Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals
ATJ Murk, E Rijntjes, BJ Blaauboer, R Clewell, KM Crofton, ...
Toxicology in vitro 27 (4), 1320-1346, 2013
Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization
R Huang, M Xia, S Sakamuru, J Zhao, SA Shahane, M Attene-Ramos, ...
Nature communications 7 (1), 1-10, 2016
Molecular signatures associated with ZIKV exposure in human cortical neural progenitors
F Zhang, C Hammack, SC Ogden, Y Cheng, EM Lee, Z Wen, X Qian, ...
Nucleic acids research 44 (18), 8610-8620, 2016
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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