| High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-κB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway FM Ho, WW Lin, BC Chen, CM Chao, CR Yang, LY Lin, CC Lai, SH Liu, ... Cellular signalling 18 (3), 391-399, 2006 | 308 | 2006 |
| Soluble decoy receptor 3 induces angiogenesis by neutralization of TL1A, a cytokine belonging to tumor necrosis factor superfamily and exhibiting angiostatic action CR Yang, SL Hsieh, CM Teng, FM Ho, WL Su, WW Lin Cancer Research 64 (3), 1122-1129, 2004 | 160 | 2004 |
| Decoy receptor 3 increases monocyte adhesion to endothelial cells via NF-κB-dependent up-regulation of intercellular adhesion molecule-1, VCAM-1, and IL-8 expression CR Yang, SL Hsieh, FM Ho, WW Lin The journal of immunology 174 (3), 1647-1656, 2005 | 149 | 2005 |
| Histone deacetylase inhibitors increase microRNA-146a expression and enhance negative regulation of interleukin-1β signaling in osteoarthritis fibroblast-like synoviocytes JH Wang, KS Shih, YW Wu, AW Wang, CR Yang Osteoarthritis and cartilage 21 (12), 1987-1996, 2013 | 110 | 2013 |
| Decoy receptor 3 (DcR3) induces osteoclast formation from monocyte/macrophage lineage precursor cells CR Yang, JH Wang, SL Hsieh, SM Wang, TL Hsu, WW Lin Cell Death & Differentiation 11 (1), S97-S107, 2004 | 98 | 2004 |
| Aciculatin inhibits lipopolysaccharide-mediated inducible nitric oxide synthase and cyclooxygenase-2 expression via suppressing NF-κB and JNK/p38 MAPK activation pathways IN Hsieh, ASY Chang, CM Teng, CC Chen, CR Yang Journal of Biomedical Science 18, 1-11, 2011 | 83 | 2011 |
| The novel histone de acetylase 6 inhibitor, MPT0G211, ameliorates tau phosphorylation and cognitive deficits in an Alzheimer’s disease model SJ Fan, FI Huang, JP Liou, CR Yang Cell death & disease 9 (6), 655, 2018 | 78 | 2018 |
| (N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo HY Lee, K Nepali, FI Huang, CY Chang, MJ Lai, YH Li, HL Huang, ... Journal of medicinal chemistry 61 (3), 905-917, 2018 | 71 | 2018 |
| 5-Aroylindoles act as selective histone deacetylase 6 inhibitors ameliorating Alzheimer’s disease phenotypes HY Lee, SJ Fan, FI Huang, HY Chao, KC Hsu, TE Lin, TK Yeh, MJ Lai, ... Journal of Medicinal Chemistry 61 (16), 7087-7102, 2018 | 67 | 2018 |
| Intracerebral transplantation of neural stem cells combined with trehalose ingestion alleviates pathology in a mouse model of Huntington's disease CR Yang, RK Yu Journal of neuroscience research 87 (1), 26-33, 2009 | 62 | 2009 |
| Decoy receptor 3 expression in AsPC-1 human pancreatic adenocarcinoma cells via the phosphatidylinositol 3-kinase-, Akt-, and NF-κB-dependent pathway PH Chen, CR Yang The Journal of Immunology 181 (12), 8441-8449, 2008 | 54 | 2008 |
| Denbinobin upregulates miR-146a expression and attenuates IL-1β-induced upregulation of ICAM-1 and VCAM-1 expressions in osteoarthritis fibroblast-like synoviocytes CR Yang, KS Shih, JP Liou, YW Wu, IN Hsieh, HY Lee, TC Lin, JH Wang Journal of Molecular Medicine 92, 1147-1158, 2014 | 49 | 2014 |
| Indole-3-ethylsulfamoylphenylacrylamides: potent histone deacetylase inhibitors with anti-inflammatory activity S Mehndiratta, YL Hsieh, YM Liu, AW Wang, HY Lee, LY Liang, S Kumar, ... European Journal of Medicinal Chemistry 85, 468-479, 2014 | 48 | 2014 |
| 3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activity HY Lee, JF Lee, S Kumar, YW Wu, WC HuangFu, MJ Lai, YH Li, ... European journal of medicinal chemistry 125, 1268-1278, 2017 | 41 | 2017 |
| Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model JH Wang, KS Shih, JP Liou, YW Wu, ASY Chang, KL Wang, CL Tsai, ... PLoS One 7 (2), e31368, 2012 | 39 | 2012 |
| Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo YL Hsieh, HJ Tu, SL Pan, JP Liou, CR Yang Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1866 (6), 992-1003, 2019 | 36 | 2019 |
| Preclinical anti-arthritic study and pharmacokinetic properties of a potent histone deacetylase inhibitor MPT0G009 IN Hsieh, JP Liou, HY Lee, MJ Lai, YH Li, CR Yang Cell death & disease 5 (4), e1166-e1166, 2014 | 35 | 2014 |
| Thiazolidinediones inhibit TNF-α-mediated osteoclast differentiation of RAW264. 7 macrophages and mouse bone marrow cells through downregulation of NFATC1 CR Yang, CC Lai Shock 33 (6), 662-667, 2010 | 34 | 2010 |
| 2-(Phenylsulfonyl) quinoline N-hydroxyacrylamides as potent anticancer agents inhibiting histone deacetylase HY Lee, CY Chang, CJ Su, HL Huang, S Mehndiratta, YH Chao, CM Hsu, ... European Journal of Medicinal Chemistry 122, 92-101, 2016 | 31 | 2016 |
| Anticancer activity of MPT0G157, a derivative of indolylbenzenesulfonamide, inhibits tumor growth and angiogenesis YC Huang, FI Huang, S Mehndiratta, SC Lai, JP Liou, CR Yang Oncotarget 6 (21), 18590, 2015 | 30 | 2015 |
