The NALP3 inflammasome is involved in the innate immune response to amyloid-β A Halle, V Hornung, GC Petzold, CR Stewart, BG Monks, T Reinheckel, ... Nature immunology 9 (8), 857-865, 2008 | 2694 | 2008 |
Degradation of oxidized proteins in mammalian cells T Grune, T Reinheckel, KJA Davies The FASEB Journal 11 (7), 526-534, 1997 | 1043 | 1997 |
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis W Halangk, MM Lerch, B Brandt-Nedelev, W Roth, M Ruthenbuerger, ... The Journal of clinical investigation 106 (6), 773-781, 2000 | 736 | 2000 |
Specialized roles for cysteine cathepsins in health and disease J Reiser, B Adair, T Reinheckel The Journal of clinical investigation 120 (10), 3421-3431, 2010 | 643 | 2010 |
Distinct roles for cysteine cathepsin genes in multistage tumorigenesis V Gocheva, W Zeng, D Ke, D Klimstra, T Reinheckel, C Peters, ... Genes & development 20 (5), 543-556, 2006 | 638 | 2006 |
Emerging roles of cysteine cathepsins in disease and their potential as drug targets O Vasiljeva, T Reinheckel, C Peters, D Turk, V Turk, B Turk Current pharmaceutical design 13 (4), 387-403, 2007 | 563 | 2007 |
Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation MK Liszewski, M Kolev, G Le Friec, M Leung, PG Bertram, AF Fara, ... Immunity 39 (6), 1143-1157, 2013 | 536 | 2013 |
Comparative resistance of the 20S and 26S proteasome to oxidative stress T REINHECKEL, N SITTE, O ULLRICH, U KUCKELKORN, KJA DAVIES, ... Biochemical Journal 335 (3), 637-642, 1998 | 499 | 1998 |
Proteolysis in Cultured Liver Epithelial Cells during Oxidative Stress: ROLE OF THE MULTICATALYTIC PROTEINASE COMPLEX, PROTEASOME (∗) T Grune, T Reinheckel, M Joshi, KJA Davies Journal of Biological Chemistry 270 (5), 2344-2351, 1995 | 482 | 1995 |
Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment G Mikhaylov, U Mikac, AA Magaeva, VI Itin, EP Naiden, I Psakhye, ... Nature nanotechnology 6 (9), 594-602, 2011 | 428 | 2011 |
Tumor cell–derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer O Vasiljeva, A Papazoglou, A Krüger, H Brodoefel, M Korovin, ... Cancer research 66 (10), 5242-5250, 2006 | 421 | 2006 |
Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome T Grune, T Reinheckel, KJA Davies Journal of Biological Chemistry 271 (26), 15504-15509, 1996 | 406 | 1996 |
Cathepsin L is required for endothelial progenitor cell–induced neovascularization C Urbich, C Heeschen, A Aicher, K Sasaki, T Bruhl, MR Farhadi, ... Nature medicine 11 (2), 206-213, 2005 | 372 | 2005 |
Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation S Conus, R Perozzo, T Reinheckel, C Peters, L Scapozza, S Yousefi, ... The Journal of experimental medicine 205 (3), 685-698, 2008 | 319 | 2008 |
Thyroid functions of mouse cathepsins B, K, and L B Friedrichs, C Tepel, T Reinheckel, J Deussing, K von Figura, V Herzog, ... The Journal of clinical investigation 111 (11), 1733-1745, 2003 | 296 | 2003 |
Poly-ADP ribose polymerase activates nuclear proteasome to degrade oxidatively damaged histones O Ullrich, T Reinheckel, N Sitte, R Hass, T Grune, KJA Davies Proceedings of the National Academy of Sciences 96 (11), 6223-6228, 1999 | 283 | 1999 |
Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter S Yasothornsrikul, D Greenbaum, KF Medzihradszky, T Toneff, R Bundey, ... Proceedings of the National Academy of Sciences 100 (16), 9590-9595, 2003 | 246 | 2003 |
Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L J Stypmann, K Gläser, W Roth, DJ Tobin, I Petermann, R Matthias, ... Proceedings of the National Academy of Sciences 99 (9), 6234-6239, 2002 | 243 | 2002 |
Towards Specific Functions of Lysosomal Cysteine Peptidases: Phenotypes of Mice Deficient for Cathepsin Β or Cathepsin L T Reinheckel, J Deussing, W Roth, C Peters Biological chemistry 382 (5), 735-742, 2001 | 235 | 2001 |
Osteoclastic bone degradation and the role of different cysteine proteinases and matrix metalloproteinases: differences between calvaria and long bone V Everts, W Korper, KA Hoeben, IDC Jansen, D Bromme, KBJM Cleutjens, ... Journal of Bone and Mineral Research 21 (9), 1399-1408, 2006 | 223 | 2006 |