Vishva Dixit
Vishva Dixit
vice-president, Genentech
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Citata da
Citata da
Death receptors: signaling and modulation
A Ashkenazi, VM Dixit
science, 1305-1308, 1998
FLICE, a novel FADD-homologous ICE/CED-3–like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
M Muzio, AM Chinnaiyan, FC Kischkel, K O'Rourke, A Shevchenko, J Ni, ...
Cell 85 (6), 817-827, 1996
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
AM Chinnaiyan, K O'Rourke, M Tewari, VM Dixit
Cell 81 (4), 505-512, 1995
Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase
M Tewari, LT Quan, K O'Rourke, S Desnoyers, Z Zeng, DR Beidler, ...
Cell 81 (5), 801-809, 1995
Cryopyrin activates the inflammasome in response to toxins and ATP
S Mariathasan, DS Weiss, K Newton, J McBride, K O'Rourke, ...
Nature 440 (7081), 228-232, 2006
Caspases: intracellular signaling by proteolysis
GS Salvesen, VM Dixit
Cell 91 (4), 443-446, 1997
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway requirement for Flk-1/KDR…
HP Gerber, A McMurtrey, J Kowalski, M Yan, BA Keyt, V Dixit, N Ferrara
Journal of Biological Chemistry 273 (46), 30336-30343, 1998
The receptor for the cytotoxic ligand TRAIL
G Pan, K O'Rourke, AM Chinnaiyan, R Gentz, R Ebner, J Ni, VM Dixit
Science 276 (5309), 111-113, 1997
Apoptosis signaling
A Strasser, L O'Connor, VM Dixit
Annual review of biochemistry 69 (1), 217-245, 2000
An antagonist decoy receptor and a death domain-containing receptor for TRAIL
G Pan, J Ni, YF Wei, G Yu, R Gentz, VM Dixit
Science 277 (5327), 815-818, 1997
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
IE Wertz, KM O'rourke, H Zhou, M Eby, L Aravind, S Seshagiri, P Wu, ...
Nature 430 (7000), 694-699, 2004
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
S Mariathasan, K Newton, DM Monack, D Vucic, DM French, WP Lee, ...
Nature 430 (6996), 213-218, 2004
Apoptosis control by death and decoy receptors
A Ashkenazi, VM Dixit
Current opinion in cell biology 11 (2), 255-260, 1999
Non-canonical inflammasome activation targets caspase-11
N Kayagaki, S Warming, M Lamkanfi, LV Walle, S Louie, J Dong, ...
Nature 479 (7371), 117-121, 2011
An induced proximity model for caspase-8 activation
M Muzio, BR Stockwell, HR Stennicke, GS Salvesen, VM Dixit
Journal of Biological Chemistry 273 (5), 2926-2930, 1998
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
M Muzio, J Ni, P Feng, VM Dixit
Science 278 (5343), 1612-1615, 1997
Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells
HP Gerber, V Dixit, N Ferrara
Journal of biological chemistry 273 (21), 13313-13316, 1998
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40
M Rothe, V Sarma, VM Dixit, DV Goeddel
Science 269 (5229), 1424-1427, 1995
Mechanisms and functions of inflammasomes
M Lamkanfi, VM Dixit
Cell 157 (5), 1013-1022, 2014
Caspase activation: the induced-proximity model
GS Salvesen, VM Dixit
Proceedings of the National Academy of Sciences 96 (20), 10964-10967, 1999
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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