John M Burke
John M Burke
President and CEO, Applied BioMath
Email verificata su appliedbiomath.com - Home page
TitoloCitata daAnno
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
SL Spencer, S Gaudet, JG Albeck, JM Burke, PK Sorger
Nature 459 (7245), 428, 2009
8902009
Physicochemical modelling of cell signalling pathways
BB Aldridge, JM Burke, DA Lauffenburger, PK Sorger
Nature cell biology 8 (11), 1195, 2006
6362006
Quantitative analysis of pathways controlling extrinsic apoptosis in single cells
JG Albeck, JM Burke, BB Aldridge, M Zhang, DA Lauffenburger, ...
Molecular cell 30 (1), 11-25, 2008
3642008
Modeling a snap-action, variable-delay switch controlling extrinsic cell death
JG Albeck, JM Burke, SL Spencer, DA Lauffenburger, PK Sorger
PLoS biology 6 (12), e299, 2008
2812008
Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks
DC Kirouac, J Saez-Rodriguez, J Swantek, JM Burke, DA Lauffenburger, ...
BMC systems biology 6 (1), 29, 2012
742012
Computational modelling of ErbB family phosphorylation dynamics in response to transforming growth factor alpha and heregulin indicates spatial compartmentation of phosphatase …
BS Hendriks, J Cook, JM Burke, JM Beusmans, DA Lauffenburger, ...
IEE Proceedings-Systems Biology 153 (1), 22-33, 2006
442006
Profiling drugs for rheumatoid arthritis that inhibit synovial fibroblast activation
DS Jones, AP Jenney, JL Swantek, JM Burke, DA Lauffenburger, ...
Nature chemical biology 13 (1), 38, 2017
282017
Quantitative Systems Pharmacology Model of hUGT1A1‐modRNA Encoding for the UGT1A1 Enzyme to Treat Crigler‐Najjar Syndrome Type 1
JF Apgar, JP Tang, P Singh, N Balasubramanian, J Burke, MR Hodges, ...
CPT: pharmacometrics & systems pharmacology 7 (6), 404-412, 2018
52018
QUANTITATIVE SYSTEMS PHARMACOLOGY MODEL FOR THE RATIONAL DESIGN AND CLINICAL TRANSLATION OF A MASKED, TUMOR-ACTIVATED ANTIBODY.
M Stroh, J Sagert, BL Miliard, L Lin, JF Apgar, JM Burke, W Kavanaugh
CLINICAL PHARMACOLOGY & THERAPEUTICS 103, S88-S88, 2018
12018
A quantitative systems pharmacology model of colonic motility with applications in drug development
R Das, L Wille, L Zhang, C Chen, W Winchester, J Selimkhanov, ...
Journal of pharmacokinetics and pharmacodynamics, 1-14, 2019
2019
Systemic Calibration of a Cell Signaling Network Model
SL Spencer, JG Albeck, JM Burke, PK Sorger, S Gaudet, K Kim, DH Kim
BioMed Central, 2010
2010
Single-Cell Math Model With Experimental And Math Analysis Of The Apoptosis Regulatory Network
JM Burke, JG Albeck, PK Sorger, DA Lauffenburger
The 2007 Annual Meeting, 2007
2007
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
Articoli 1–12