Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis V Makarov, G Manina, K Mikusova, U Möllmann, O Ryabova, ... Science 324 (5928), 801-804, 2009 | 839 | 2009 |
Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms G Manina, N Dhar, JD McKinney Cell host & microbe 17 (1), 32-46, 2015 | 305 | 2015 |
Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5–MmpL5 efflux system A Milano, MR Pasca, R Provvedi, AP Lucarelli, G Manina, ALJL Ribeiro, ... Tuberculosis 89 (1), 84-90, 2009 | 206 | 2009 |
Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome P Guglierame, MR Pasca, E De Rossi, S Buroni, P Arrigo, G Manina, ... BMC microbiology 6, 1-14, 2006 | 124 | 2006 |
The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis G Riccardi, MR Pasca, LR Chiarelli, G Manina, A Mattevi, C Binda Applied microbiology and biotechnology 97, 8841-8848, 2013 | 117 | 2013 |
Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance G Manina, M Bellinzoni, MR Pasca, J Neres, A Milano, ... Molecular microbiology 77 (5), 1172-1185, 2010 | 94 | 2010 |
Decaprenylphosphoryl-β-D-ribose 2'-epimerase from Mycobacterium tuberculosis is a magic drug target G Manina, M R Pasca, S Buroni, E De Rossi, G Riccardi Current medicinal chemistry 17 (27), 3099-3108, 2010 | 90 | 2010 |
Phenotypic Heterogeneity in Mycobacterium tuberculosis N Dhar, J McKinney, G Manina Tuberculosis and the Tubercle Bacillus, 671-697, 2017 | 63 | 2017 |
A single-cell perspective on non-growing but metabolically active (NGMA) bacteria G Manina, JD McKinney Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host …, 2013 | 51 | 2013 |
LfrR Is a Repressor That Regulates Expression of the Efflux Pump LfrA in Mycobacterium smegmatis S Buroni, G Manina, P Guglierame, MR Pasca, G Riccardi, E De Rossi Antimicrobial agents and chemotherapy 50 (12), 4044-4052, 2006 | 50 | 2006 |
Preexisting variation in DNA damage response predicts the fate of single mycobacteria under stress G Manina, A Griego, LK Singh, JD McKinney, N Dhar The EMBO journal 38 (22), e101876, 2019 | 26 | 2019 |
Single-cell analysis of mycobacteria using microfluidics and time-lapse microscopy N Dhar, G Manina Mycobacteria Protocols, 241-256, 2015 | 24 | 2015 |
Listeriolysin S: A bacteriocin from Listeria monocytogenes that induces membrane permeabilization in a contact-dependent manner J Meza-Torres, M Lelek, JJ Quereda, M Sachse, G Manina, D Ershov, ... Proceedings of the National Academy of Sciences 118 (40), e2108155118, 2021 | 13 | 2021 |
6,11-Dioxobenzo[f]pyrido[1,2-a]indoles Kill Mycobacterium tuberculosis by Targeting Iron–Sulfur Protein Rv0338c (IspQ), A Putative Redox Sensor R Székely, M Rengifo-Gonzalez, V Singh, O Riabova, A Benjak, J Piton, ... ACS infectious diseases 6 (11), 3015-3025, 2020 | 7 | 2020 |
Microfluidic dose–response platform to track the dynamics of drug response in single mycobacterial cells M Mistretta, N Gangneux, G Manina Scientific Reports 12 (1), 19578, 2022 | 6 | 2022 |
Fragment-based phenotypic lead discovery to identify new drug seeds that target infectious diseases Y Ayotte, E Bernet, F Bilodeau, M Cimino, D Gagnon, M Lebughe, ... ACS Chemical Biology 16 (11), 2158-2163, 2021 | 5 | 2021 |
Chemical, Metabolic, and Cellular Characterization of a FtsZ Inhibitor Effective Against Burkholderia cenocepacia LR Chiarelli, VC Scoffone, G Trespidi, G Barbieri, O Riabova, ... Frontiers in Microbiology 11, 562, 2020 | 5 | 2020 |
RNase E and HupB dynamics foster mycobacterial cell homeostasis and fitness A Griego, T Douche, QG Gianetto, M Matondo, G Manina Iscience 25 (5), 2022 | 4 | 2022 |
Single-cell analysis of mycobacteria using microfluidics and time-lapse microscopy G Manina, N Dhar Mycobacteria Protocols, 205-229, 2021 | 2 | 2021 |
Delving into the functional meaning of phenotypic variation in mycobacterial persistence: who benefits the most from programmed death of individual cells? L Burgess Tornaletti, G Manina Microbiology Insights 13, 1178636120945304, 2020 | 2 | 2020 |