| Different types of cerebellar GABAergic interneurons originate from a common pool of multipotent progenitor cells K Leto, B Carletti, IM Williams, L Magrassi, F Rossi Journal of Neuroscience 26 (45), 11682-11694, 2006 | 171 | 2006 |
| Heat shock protein–based therapy as a potential candidate for treating the sphingolipidoses T Kirkegaard, J Gray, DA Priestman, KL Wallom, J Atkins, OD Olsen, ... Science Translational Medicine 8 (355), 355ra118-355ra118, 2016 | 169 | 2016 |
| Beneficial effects of anti-inflammatory therapy in a mouse model of Niemann-Pick disease type C1 D Smith, KL Wallom, IM Williams, M Jeyakumar, FM Platt Neurobiology of disease 36 (2), 242-251, 2009 | 169 | 2009 |
| Nerve growth factor-induced p75-mediated death of cultured hippocampal neurons is age-dependent and transduced through ceramide generated by neutral sphingomyelinase AB Brann, M Tcherpakov, IM Williams, AH Futerman, M Fainzilber Journal of Biological Chemistry 277 (12), 9812-9818, 2002 | 166 | 2002 |
| NSAIDs increase survival in the Sandhoff disease mouse: Synergy with N‐butyldeoxynojirimycin M Jeyakumar, DA Smith, IM Williams, MC Borja, DCA Neville, TD Butters, ... Annals of neurology 56 (5), 642-649, 2004 | 142 | 2004 |
| Systemic AAV9 gene therapy improves the lifespan of mice with Niemann-Pick disease, type C1 RJ Chandler, IM Williams, AL Gibson, CD Davidson, AA Incao, ... Human molecular genetics 26 (1), 52-64, 2017 | 92 | 2017 |
| Improved neuroprotection using miglustat, curcumin and ibuprofen as a triple combination therapy in Niemann–Pick disease type C1 mice IM Williams, KL Wallom, DA Smith, N Al Eisa, C Smith, FM Platt Neurobiology of disease 67, 9-17, 2014 | 85 | 2014 |
| Immune dysfunction in Niemann‐Pick disease type C N Platt, AO Speak, A Colaco, J Gray, DA Smith, IM Williams, KL Wallom, ... Journal of neurochemistry 136, 74-80, 2016 | 79 | 2016 |
| Necroptosis in Niemann–Pick disease, type C1: a potential therapeutic target A Cougnoux, C Cluzeau, S Mitra, R Li, I Williams, K Burkert, X Xu, ... Cell death & disease 7 (3), e2147-e2147, 2016 | 62 | 2016 |
| Benefit–risk profile of sphingosine-1-phosphate receptor modulators in relapsing and secondary progressive multiple sclerosis G Comi, HP Hartung, R Bakshi, IM Williams, H Wiendl Drugs 77, 1755-1768, 2017 | 61 | 2017 |
| Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes KR Francis, AN Ton, Y Xin, PE O'Halloran, CA Wassif, N Malik, ... Nature medicine 22 (4), 388-396, 2016 | 59 | 2016 |
| Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway P Fineran, E Lloyd-Evans, NA Lack, N Platt, LC Davis, AJ Morgan, ... Wellcome open research 1, 18, 2016 | 52 | 2016 |
| Time constraints and positional cues in the developing cerebellum regulate Purkinje cell placement in the cortical architecture B Carletti, IM Williams, K Leto, K Nakajima, L Magrassi, F Rossi Developmental biology 317 (1), 147-160, 2008 | 52 | 2008 |
| Multiple Sclerosis Phenotypes as a Continuum: The Role of Neurologic Reserve TL Vollmer, KV Nair, IM Williams, E Alvarez Neurology: Clinical Practice 11 (4), 342-351, 2021 | 45 | 2021 |
| Critical role of iron in the pathogenesis of the murine gangliosidoses M Jeyakumar, I Williams, DA Smith, TM Cox, FM Platt Neurobiology of disease 34 (3), 406-416, 2009 | 32 | 2009 |
| Disability outcomes in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder R Marignier, JL Bennett, HJ Kim, BG Weinshenker, SJ Pittock, ... Neurology: Neuroimmunology & Neuroinflammation 8 (3), e978, 2021 | 26 | 2021 |
| Identification of novel pathways associated with patterned cerebellar purkinje neuron degeneration in niemann-pick disease, type C1 KB Martin, IM Williams, CV Cluzeau, A Cougnoux, RK Dale, JR Iben, ... International journal of molecular sciences 21 (1), 292, 2019 | 24 | 2019 |
| Phase IV study of retention on fingolimod versus injectable multiple sclerosis therapies: a randomized clinical trial BAC Cree, DL Arnold, M Cascione, EJ Fox, IM Williams, X Meng, ... Therapeutic Advances in Neurological Disorders 11, 1756286418774338, 2018 | 24 | 2018 |
| Cerebellar granule cells transplanted in vivo can follow physiological and unusual migratory routes to integrate into the recipient cortex IM Williams, B Carletti, K Leto, L Magrassi, F Rossi Neurobiology of disease 30 (1), 139-149, 2008 | 16 | 2008 |
| Sensitivity analysis of the primary endpoint from the N-MOmentum study of inebilizumab in NMOSD BAC Cree, JL Bennett, HJ Kim, BG Weinshenker, SJ Pittock, ... Multiple Sclerosis Journal 27 (13), 2052-2061, 2021 | 14 | 2021 |
