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Shahila Mehboob
Shahila Mehboob
Verified email at uic.edu
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Cited by
Year
Nanomole-scale protein solid-state NMR by breaking intrinsic 1H T1 boundaries
NP Wickramasinghe, S Parthasarathy, CR Jones, C Bhardwaj, F Long, ...
Nature methods 6 (3), 215-218, 2009
2272009
Comparison of radii sets, entropy, QM methods, and sampling on MM‐PBSA, MM‐GBSA, and QM/MM‐GBSA ligand binding energies of F. tularensis enoyl‐ACP …
PC Su, CC Tsai, S Mehboob, KE Hevener, ME Johnson
Journal of computational chemistry 36 (25), 1859-1873, 2015
1102015
Discovery of a novel and potent class of F. tularensis enoyl-reductase (FabI) inhibitors by molecular shape and electrostatic matching
KE Hevener, S Mehboob, PC Su, K Truong, T Boci, J Deng, M Ghassemi, ...
Journal of medicinal chemistry 55 (1), 268-279, 2012
732012
Structural and functional analysis of two glutamate racemase isozymes from Bacillus anthracis and implications for inhibitor design
M May, S Mehboob, DC Mulhearn, Z Wang, H Yu, GRJ Thatcher, ...
Journal of molecular biology 371 (5), 1219-1237, 2007
662007
αβ spectrin coiled coil association at the tetramerization site
S Mehboob, BH Luo, BM Patel, LWM Fung
Biochemistry 40 (41), 12457-12464, 2001
402001
Structural analysis of the αN-terminal region of erythroid and nonerythroid spectrins by small-angle X-ray scattering
S Mehboob, J Jacob, M May, L Kotula, P Thiyagarajan, ME Johnson, ...
Biochemistry 42 (49), 14702-14710, 2003
342003
Benzimidazole-based FabI inhibitors: a promising novel scaffold for anti-staphylococcal drug development
TL Mistry, L Truong, AK Ghosh, ME Johnson, S Mehboob
ACS infectious diseases 3 (1), 54-61, 2017
322017
Crystal structure of the nonerythroid α-spectrin tetramerization site reveals differences between erythroid and nonerythroid spectrin tetramer formation
S Mehboob, Y Song, M Witek, F Long, BD Santarsiero, ME Johnson, ...
Journal of biological chemistry 285 (19), 14572-14584, 2010
322010
Structural and Enzymatic Analyses Reveal the Binding Mode of a Novel Series of Francisella tularensis Enoyl Reductase (FabI) Inhibitors
S Mehboob, KE Hevener, K Truong, T Boci, BD Santarsiero, ME Johnson
Journal of medicinal chemistry 55 (12), 5933-5941, 2012
292012
Structural and biological evaluation of a novel series of benzimidazole inhibitors of Francisella tularensis enoyl-ACP reductase (FabI)
S Mehboob, J Song, KE Hevener, PC Su, T Boci, L Brubaker, L Truong, ...
Bioorganic & medicinal chemistry letters 25 (6), 1292-1296, 2015
232015
Glutamate racemase dimerization inhibits dynamic conformational flexibility and reduces catalytic rates
S Mehboob, L Guo, W Fu, A Mittal, T Yau, K Truong, M Johlfs, F Long, ...
Biochemistry 48 (29), 7045-7055, 2009
222009
Structure of the Francisella tularensis enoyl-acyl carrier protein reductase (FabI) in complex with NAD+ and triclosan
S Mehboob, K Truong, BD Santarsiero, ME Johnson
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010
202010
Conformational studies of the tetramerization site of human erythroid spectrin by cysteine-scanning spin-labeling EPR methods
S Mehboob, BH Luo, W Fu, ME Johnson, LWM Fung
Biochemistry 44 (48), 15898-15905, 2005
202005
A novel series of enoyl reductase inhibitors targeting the ESKAPE pathogens, Staphylococcus aureus and Acinetobacter baumannii
J Kwon, T Mistry, J Ren, ME Johnson, S Mehboob
Bioorganic & medicinal chemistry 26 (1), 65-76, 2018
172018
Important region in the β‐spectrin C‐terminus for spectrin tetramer formation
BH Luo, S Mehboob, MG Hurtuk, NH Pipalia, LWM Fung
European journal of haematology 68 (2), 73-79, 2002
152002
Structure of dihydroorotase from Bacillus anthracis at 2.6 Å resolution
S Mehboob, DC Mulhearn, K Truong, ME Johnson, BD Santarsiero
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010
142010
Special challenges to the rational design of antibacterial agents
KE Hevener, S Cao, T Zhu, PC Su, S Mehboob, ME Johnson
Annual reports in medicinal chemistry 48, 283-298, 2013
132013
Special challenges to the rational design of antibacterial agents
KE Hevener, S Cao, T Zhu, PC Su, S Mehboob, ME Johnson
Annual reports in medicinal chemistry 48, 283-298, 2013
132013
Determination of absolute configuration and binding efficacy of benzimidazole-based FabI inhibitors through the support of electronic circular dichroism and MM-GBSA techniques
J Ren, TL Mistry, PC Su, S Mehboob, R Demissie, LWM Fung, AK Ghosh, ...
Bioorganic & medicinal chemistry letters 28 (11), 2074-2079, 2018
122018
Structural characterization of Porphyromonas gingivalis enoyl-ACP reductase II (FabK)
KE Hevener, BD Santarsiero, H Lee, JA Jones, T Boci, ME Johnson, ...
Acta Crystallographica Section F: Structural Biology Communications 74 (2 …, 2018
122018
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