Nanomole-scale protein solid-state NMR by breaking intrinsic 1H T1 boundaries NP Wickramasinghe, S Parthasarathy, CR Jones, C Bhardwaj, F Long, ... Nature methods 6 (3), 215-218, 2009 | 227 | 2009 |
Comparison of radii sets, entropy, QM methods, and sampling on MM‐PBSA, MM‐GBSA, and QM/MM‐GBSA ligand binding energies of F. tularensis enoyl‐ACP … PC Su, CC Tsai, S Mehboob, KE Hevener, ME Johnson Journal of computational chemistry 36 (25), 1859-1873, 2015 | 110 | 2015 |
Discovery of a novel and potent class of F. tularensis enoyl-reductase (FabI) inhibitors by molecular shape and electrostatic matching KE Hevener, S Mehboob, PC Su, K Truong, T Boci, J Deng, M Ghassemi, ... Journal of medicinal chemistry 55 (1), 268-279, 2012 | 73 | 2012 |
Structural and functional analysis of two glutamate racemase isozymes from Bacillus anthracis and implications for inhibitor design M May, S Mehboob, DC Mulhearn, Z Wang, H Yu, GRJ Thatcher, ... Journal of molecular biology 371 (5), 1219-1237, 2007 | 66 | 2007 |
αβ spectrin coiled coil association at the tetramerization site S Mehboob, BH Luo, BM Patel, LWM Fung Biochemistry 40 (41), 12457-12464, 2001 | 40 | 2001 |
Structural analysis of the αN-terminal region of erythroid and nonerythroid spectrins by small-angle X-ray scattering S Mehboob, J Jacob, M May, L Kotula, P Thiyagarajan, ME Johnson, ... Biochemistry 42 (49), 14702-14710, 2003 | 34 | 2003 |
Benzimidazole-based FabI inhibitors: a promising novel scaffold for anti-staphylococcal drug development TL Mistry, L Truong, AK Ghosh, ME Johnson, S Mehboob ACS infectious diseases 3 (1), 54-61, 2017 | 32 | 2017 |
Crystal structure of the nonerythroid α-spectrin tetramerization site reveals differences between erythroid and nonerythroid spectrin tetramer formation S Mehboob, Y Song, M Witek, F Long, BD Santarsiero, ME Johnson, ... Journal of biological chemistry 285 (19), 14572-14584, 2010 | 32 | 2010 |
Structural and Enzymatic Analyses Reveal the Binding Mode of a Novel Series of Francisella tularensis Enoyl Reductase (FabI) Inhibitors S Mehboob, KE Hevener, K Truong, T Boci, BD Santarsiero, ME Johnson Journal of medicinal chemistry 55 (12), 5933-5941, 2012 | 29 | 2012 |
Structural and biological evaluation of a novel series of benzimidazole inhibitors of Francisella tularensis enoyl-ACP reductase (FabI) S Mehboob, J Song, KE Hevener, PC Su, T Boci, L Brubaker, L Truong, ... Bioorganic & medicinal chemistry letters 25 (6), 1292-1296, 2015 | 23 | 2015 |
Glutamate racemase dimerization inhibits dynamic conformational flexibility and reduces catalytic rates S Mehboob, L Guo, W Fu, A Mittal, T Yau, K Truong, M Johlfs, F Long, ... Biochemistry 48 (29), 7045-7055, 2009 | 22 | 2009 |
Structure of the Francisella tularensis enoyl-acyl carrier protein reductase (FabI) in complex with NAD+ and triclosan S Mehboob, K Truong, BD Santarsiero, ME Johnson Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010 | 20 | 2010 |
Conformational studies of the tetramerization site of human erythroid spectrin by cysteine-scanning spin-labeling EPR methods S Mehboob, BH Luo, W Fu, ME Johnson, LWM Fung Biochemistry 44 (48), 15898-15905, 2005 | 20 | 2005 |
A novel series of enoyl reductase inhibitors targeting the ESKAPE pathogens, Staphylococcus aureus and Acinetobacter baumannii J Kwon, T Mistry, J Ren, ME Johnson, S Mehboob Bioorganic & medicinal chemistry 26 (1), 65-76, 2018 | 17 | 2018 |
Important region in the β‐spectrin C‐terminus for spectrin tetramer formation BH Luo, S Mehboob, MG Hurtuk, NH Pipalia, LWM Fung European journal of haematology 68 (2), 73-79, 2002 | 15 | 2002 |
Structure of dihydroorotase from Bacillus anthracis at 2.6 Å resolution S Mehboob, DC Mulhearn, K Truong, ME Johnson, BD Santarsiero Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010 | 14 | 2010 |
Special challenges to the rational design of antibacterial agents KE Hevener, S Cao, T Zhu, PC Su, S Mehboob, ME Johnson Annual reports in medicinal chemistry 48, 283-298, 2013 | 13 | 2013 |
Special challenges to the rational design of antibacterial agents KE Hevener, S Cao, T Zhu, PC Su, S Mehboob, ME Johnson Annual reports in medicinal chemistry 48, 283-298, 2013 | 13 | 2013 |
Determination of absolute configuration and binding efficacy of benzimidazole-based FabI inhibitors through the support of electronic circular dichroism and MM-GBSA techniques J Ren, TL Mistry, PC Su, S Mehboob, R Demissie, LWM Fung, AK Ghosh, ... Bioorganic & medicinal chemistry letters 28 (11), 2074-2079, 2018 | 12 | 2018 |
Structural characterization of Porphyromonas gingivalis enoyl-ACP reductase II (FabK) KE Hevener, BD Santarsiero, H Lee, JA Jones, T Boci, ME Johnson, ... Acta Crystallographica Section F: Structural Biology Communications 74 (2 …, 2018 | 12 | 2018 |