| Oxidation of either methionine 351 or methionine 358 in α1-antitrypsin causes loss of anti-neutrophil elastase activity C Taggart, D Cervantes-Laurean, G Kim, NG McElvaney, N Wehr, J Moss, ... Journal of Biological Chemistry 275 (35), 27258-27265, 2000 | 418 | 2000 |
| Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers M Shyamsundar, STW McKeown, CM O'Kane, TR Craig, V Brown, ... American journal of respiratory and critical care medicine 179 (12), 1107-1114, 2009 | 315 | 2009 |
| Neutrophil elastase up-regulates interleukin-8 via toll-like receptor 4 JM Devaney, CM Greene, CC Taggart, TP Carroll, SJ O’Neill, ... FEBS letters 544 (1-3), 129-132, 2003 | 293 | 2003 |
| TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells CM Greene, TP Carroll, SGJ Smith, CC Taggart, J Devaney, S Griffin, ... The Journal of Immunology 174 (3), 1638-1646, 2005 | 287 | 2005 |
| Secretory leucoprotease inhibitor binds to NF-κB binding sites in monocytes and inhibits p65 binding CC Taggart, SA Cryan, S Weldon, A Gibbons, CM Greene, E Kelly, ... The Journal of experimental medicine 202 (12), 1659-1668, 2005 | 279 | 2005 |
| Secretory leucoprotease inhibitor binds to NF-κB binding sites in monocytes and inhibits p65 binding CC Taggart, SA Cryan, S Weldon, A Gibbons, CM Greene, E Kelly, ... The Journal of experimental medicine 202 (12), 1659-1668, 2005 | 279 | 2005 |
| Inactivation of human β-defensins 2 and 3 by elastolytic cathepsins CC Taggart, CM Greene, SG Smith, RL Levine, PB McCray, S O’Neill, ... The Journal of Immunology 171 (2), 931-937, 2003 | 260 | 2003 |
| Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor CC Taggart, GJ Lowe, CM Greene, AT Mulgrew, SJ O'Neill, RL Levine, ... Journal of biological chemistry 276 (36), 33345-33352, 2001 | 221 | 2001 |
| Activation of endoplasmic reticulum-specific stress responses associated with the conformational disease Z α1-antitrypsin deficiency MW Lawless, CM Greene, A Mulgrew, CC Taggart, SJ O’Neill, ... The Journal of Immunology 172 (9), 5722-5726, 2004 | 219 | 2004 |
| Interleukin-8 up-regulation by neutrophil elastase is mediated by MyD88/IRAK/TRAF-6 in human bronchial epithelium DE Walsh, CM Greene, TP Carroll, CC Taggart, PM Gallagher, SJ O'Neill, ... Journal of Biological Chemistry 276 (38), 35494-35499, 2001 | 207 | 2001 |
| Z α1-antitrypsin polymerizes in the lung and acts as a neutrophil chemoattractant AT Mulgrew, CC Taggart, MW Lawless, CM Greene, ML Brantly, ... Chest 125 (5), 1952-1957, 2004 | 202 | 2004 |
| Loss of microbicidal activity and increased formation of biofilm due to decreased lactoferrin activity in patients with cystic fibrosis MP Rogan, CC Taggart, CM Greene, PG Murphy, SJ O'Neill, ... The Journal of infectious diseases 190 (7), 1245-1253, 2004 | 201 | 2004 |
| Antimicrobial proteins and polypeptides in pulmonary innate defence MP Rogan, P Geraghty, CM Greene, SJ O'Neill, CC Taggart, ... Respiratory research 7, 1-11, 2006 | 193 | 2006 |
| Gentamicin-loaded nanoparticles show improved antimicrobial effects towards Pseudomonas aeruginosa infection SM Abdelghany, DJ Quinn, RJ Ingram, BF Gilmore, RF Donnelly, ... International journal of nanomedicine, 4053-4063, 2012 | 184 | 2012 |
| Secretory leucoprotease inhibitor prevents lipopolysaccharide-induced IκBα degradation without affecting phosphorylation or ubiquitination CC Taggart, CM Greene, NG McElvaney, S O'Neill Journal of Biological Chemistry 277 (37), 33648-33653, 2002 | 176 | 2002 |
| Increased elastase release by CF neutrophils is mediated by tumor necrosis factor-α and interleukin-8 C Taggart, RJ Coakley, P Greally, G Canny, SJ O'Neill, NG McElvaney American Journal of Physiology-Lung Cellular and Molecular Physiology 278 (1 …, 2000 | 168 | 2000 |
| Antimicrobial efficacy of tobramycin polymeric nanoparticles for Pseudomonas aeruginosa infections in cystic fibrosis: formulation, characterisation and functionalisation with … J Deacon, SM Abdelghany, DJ Quinn, D Schmid, J Megaw, RF Donnelly, ... Journal of Controlled Release 198, 55-61, 2015 | 155 | 2015 |
| Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation S Weldon, P McNally, NG McElvaney, JS Elborn, DF McAuley, J Wartelle, ... The Journal of Immunology 183 (12), 8148-8156, 2009 | 151 | 2009 |
| Respiratory epithelial cells require Toll-like receptor 4 for induction of human β-defensin 2 by lipopolysaccharide R MacRedmond, C Greene, CC Taggart, N McElvaney, S O'Neill Respiratory research 6, 1-11, 2005 | 147 | 2005 |
| Cytosolic pH and the inflammatory microenvironment modulate cell death in human neutrophils after phagocytosis RJ Coakley, C Taggart, NG McElvaney, SJ O'Neill Blood, The Journal of the American Society of Hematology 100 (9), 3383-3391, 2002 | 147 | 2002 |
