Synthetic biology: applications come of age AS Khalil, JJ Collins Nature Reviews Genetics 11 (5), 367-379, 2010 | 1734 | 2010 |
Antibiotics induce redox-related physiological alterations as part of their lethality DJ Dwyer, PA Belenky, JH Yang, IC MacDonald, JD Martell, N Takahashi, ... Proceedings of the National Academy of Sciences 111 (20), E2100-E2109, 2014 | 916 | 2014 |
Antibiotic efficacy is linked to bacterial cellular respiration MA Lobritz, P Belenky, CBM Porter, A Gutierrez, JH Yang, EG Schwarz, ... Proceedings of the National Academy of Sciences 112 (27), 8173-8180, 2015 | 733 | 2015 |
Signaling-mediated bacterial persister formation NM Vega, KR Allison, AS Khalil, JJ Collins Nature chemical biology 8 (5), 431-433, 2012 | 486 | 2012 |
Next-generation synthetic gene networks TK Lu, AS Khalil, JJ Collins Nature biotechnology 27 (12), 1139-1150, 2009 | 460 | 2009 |
A synthetic biology framework for programming eukaryotic transcription functions AS Khalil, TK Lu, CJ Bashor, CL Ramirez, NC Pyenson, JK Joung, ... Cell 150 (3), 647-658, 2012 | 416 | 2012 |
Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation X Zheng, J Krakowiak, N Patel, A Beyzavi, J Ezike, AS Khalil, D Pincus elife 5, e18638, 2016 | 249 | 2016 |
Precise, automated control of conditions for high-throughput growth of yeast and bacteria with eVOLVER BG Wong, CP Mancuso, S Kiriakov, CJ Bashor, AS Khalil Nature biotechnology 36 (7), 614-623, 2018 | 246 | 2018 |
Prospective isolation of NKX2-1–expressing human lung progenitors derived from pluripotent stem cells F Hawkins, P Kramer, A Jacob, I Driver, DC Thomas, KB McCauley, ... The Journal of clinical investigation 127 (6), 2277-2294, 2017 | 220 | 2017 |
Tissue Elasticity Estimation with Optical Coherence Elastography: Toward Mechanical Characterization of In Vivo Soft Tissue AS Khalil, RC Chan, AH Chau, BE Bouma, MRK Mofrad Annals of biomedical engineering 33, 1631-1639, 2005 | 199 | 2005 |
Functional genomics of the rapidly replicating bacterium Vibrio natriegens by CRISPRi HH Lee, N Ostrov, BG Wong, MA Gold, AS Khalil, GM Church Nature microbiology 4 (7), 1105-1113, 2019 | 184 | 2019 |
Kinesin's cover-neck bundle folds forward to generate force AS Khalil, DC Appleyard, AK Labno, A Georges, M Karplus, AM Belcher, ... Proceedings of the National Academy of Sciences 105 (49), 19247-19252, 2008 | 173 | 2008 |
Using targeted chromatin regulators to engineer combinatorial and spatial transcriptional regulation AJ Keung, CJ Bashor, S Kiriakov, JJ Collins, AS Khalil Cell 158 (1), 110-120, 2014 | 172 | 2014 |
Hsf1 and Hsp70 constitute a two-component feedback loop that regulates the yeast heat shock response J Krakowiak, X Zheng, N Patel, ZA Feder, J Anandhakumar, K Valerius, ... Elife 7, e31668, 2018 | 147 | 2018 |
Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies CJ Bashor, N Patel, S Choubey, A Beyzavi, J Kondev, JJ Collins, ... Science 364 (6440), 593-597, 2019 | 142 | 2019 |
Functional endothelialized microvascular networks with circular cross-sections in a tissue culture substrate JT Borenstein, MM Tupper, PJ Mack, EJ Weinberg, AS Khalil, J Hsiao, ... Biomedical microdevices 12, 71-79, 2010 | 142 | 2010 |
Single M13 bacteriophage tethering and stretching AS Khalil, JM Ferrer, RR Brau, ST Kottmann, CJ Noren, MJ Lang, ... Proceedings of the National Academy of Sciences 104 (12), 4892-4897, 2007 | 142 | 2007 |
OCT-based arterial elastography: robust estimation exploiting tissue biomechanics RC Chan, AH Chau, WC Karl, S Nadkarni, AS Khalil, N Iftimia, M Shishkov, ... Optics Express 12 (19), 4558-4572, 2004 | 140 | 2004 |
Chromatin regulation at the frontier of synthetic biology AJ Keung, JK Joung, AS Khalil, JJ Collins Nature Reviews Genetics 16 (3), 159-171, 2015 | 123 | 2015 |
Modular design of synthetic receptors for programmed gene regulation in cell therapies I Zhu, R Liu, JM Garcia, A Hyrenius-Wittsten, DI Piraner, J Alavi, DV Israni, ... Cell 185 (8), 1431-1443. e16, 2022 | 121 | 2022 |