Gianluigi Giannelli
Gianluigi Giannelli
Direttore Scientifico IRCCS "Saverio de Bellis"
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Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5
G Giannelli, J Falk-Marzillier, O Schiraldi, WG Stetler-Stevenson, ...
Science 277 (5323), 225-228, 1997
Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5
N Koshikawa, G Giannelli, V Cirulli, K Miyazaki, V Quaranta
The Journal of cell biology 148 (3), 615-624, 2000
Laminin-5 with transforming growth factor-β1 induces epithelial to mesenchymal transition in hepatocellular carcinoma
G Giannelli, C Bergamini, E Fransvea, C Sgarra, S Antonaci
Gastroenterology 129 (5), 1375-1383, 2005
TGF‐β signalling and liver disease
I Fabregat, J Moreno‐Cŕceres, A Sánchez, S Dooley, B Dewidar, ...
The FEBS journal 283 (12), 2219-2232, 2016
Blocking transforming growth factor–beta up‐regulates E‐cadherin and reduces migration and invasion of hepatocellular carcinoma cells
E Fransvea, U Angelotti, S Antonaci, G Giannelli
Hepatology 47 (5), 1557-1566, 2008
Clinical role of MMP‐2/TIMP‐2 imbalance in hepatocellular carcinoma
G Giannelli, C Bergamini, F Marinosci, E Fransvea, M Quaranta, L Lupo, ...
International journal of cancer 97 (4), 425-431, 2002
Role of epithelial to mesenchymal transition in hepatocellular carcinoma
G Giannelli, P Koudelkova, F Dituri, W Mikulits
Journal of hepatology 65 (4), 798-808, 2016
Transforming growth factor-β as a therapeutic target in hepatocellular carcinoma
G Giannelli, E Villa, M Lahn
Cancer research 74 (7), 1890-1894, 2014
Transforming growth factor-β1 triggers hepatocellular carcinoma invasiveness via α3β1 integrin
G Giannelli, E Fransvea, F Marinosci, C Bergamini, S Colucci, O Schiraldi, ...
The American journal of pathology 161 (1), 183-193, 2002
Drug-loaded polyelectrolyte microcapsules for sustained targeting of cancer cells
V Vergaro, F Scarlino, C Bellomo, R Rinaldi, D Vergara, M Maffia, ...
Advanced drug delivery reviews 63 (9), 847-864, 2011
Human hepatocellular carcinoma (HCC) cells require both α3β1 integrin and matrix metalloproteinases activity for migration and invasion
G Giannelli, C Bergamini, E Fransvea, F Marinosci, V Quaranta, ...
Laboratory investigation 81 (4), 613-627, 2001
Down‐regulation of connective tissue growth factor by inhibition of transforming growth factor β blocks the tumor–stroma cross‐talk and tumor progression in hepatocellular …
A Mazzocca, E Fransvea, F Dituri, L Lupo, S Antonaci, G Giannelli
Hepatology 51 (2), 523-534, 2010
MMP-2, MMP-9, TIMP-1 and TIMP-2 levels in patients with rheumatoid arthritis and psoriatic arthritis
G Giannelli, R Erriquez, F Iannone, F Marinosci, G Lapadula, S Antonaci
Clinical and experimental rheumatology 22 (3), 335-338, 2004
Targeting transforming growth factor (TGF)‐βRI inhibits activation of β1 integrin and blocks vascular invasion in hepatocellular carcinoma
E Fransvea, A Mazzocca, S Antonaci, G Giannelli
Hepatology 49 (3), 839-850, 2009
AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in non-alcoholic and alcoholic fatty liver disease
G Beale, D Chattopadhyay, J Gray, S Stewart, M Hudson, C Day, ...
BMC cancer 8 (1), 200, 2008
Dietary fiber and health outcomes: an umbrella review of systematic reviews and meta-analyses
N Veronese, M Solmi, MG Caruso, G Giannelli, AR Osella, E Evangelou, ...
The American journal of clinical nutrition 107 (3), 436-444, 2018
Neoangiogenesis-related genes are hallmarks of fast-growing hepatocellular carcinomas and worst survival. Results from a prospective study
E Villa, R Critelli, B Lei, G Marzocchi, C Cammŕ, G Giannelli, P Pontisso, ...
Gut 65 (5), 861-869, 2016
Biological and clinical relevance of Laminin-5 in cancer
G Giannelli, S Antonaci
Clinical & experimental metastasis 18 (6), 439-443, 2000
Inhibition of transforming growth factor β receptor I kinase blocks hepatocellular carcinoma growth through neo‐angiogenesis regulation
A Mazzocca, E Fransvea, G Lavezzari, S Antonaci, G Giannelli
Hepatology 50 (4), 1140-1151, 2009
Laminin-5 chains are expressed differentially in metastatic and nonmetastatic hepatocellular carcinoma
G Giannelli, E Fransvea, C Bergamini, F Marinosci, S Antonaci
Clinical cancer research 9 (10), 3684-3691, 2003
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