eloise mastrangelo
eloise mastrangelo
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Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug
E Mastrangelo, M Pezzullo, T De Burghgraeve, S Kaptein, B Pastorino, ...
Journal of Antimicrobial Chemotherapy 67 (8), 1884-1894, 2012
Structure and functionality in flavivirus NS-proteins: perspectives for drug design
M Bollati, K Alvarez, R Assenberg, C Baronti, B Canard, S Cook, ...
Antiviral research 87 (2), 125-148, 2010
Crystal structure of a novel conformational state of the flavivirus NS3 protein: implications for polyprotein processing and viral replication
R Assenberg, E Mastrangelo, TS Walter, A Verma, M Milani, RJ Owens, ...
Journal of virology 83 (24), 12895-12906, 2009
Ebolavirus and Marburgvirus: insight the Filoviridae family
P Ascenzi, A Bocedi, J Heptonstall, MR Capobianchi, A Di Caro, ...
Molecular aspects of medicine 29 (3), 151-185, 2008
Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib
D Lecis, C Drago, L Manzoni, P Seneci, C Scolastico, E Mastrangelo, ...
British journal of cancer 102 (12), 1707-1716, 2010
Structure-based inhibition of Norovirus RNA-dependent RNA polymerases
E Mastrangelo, M Pezzullo, D Tarantino, R Petazzi, F Germani, D Kramer, ...
Journal of molecular biology 419 (3-4), 198-210, 2012
Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein
E Mastrangelo, M Milani, M Bollati, B Selisko, F Peyrane, V Pandini, ...
Journal of molecular biology 372 (2), 444-455, 2007
Recognition of RNA cap in the Wesselsbron virus NS5 methyltransferase domain: implications for RNA-capping mechanisms in Flavivirus
M Bollati, M Milani, E Mastrangelo, S Ricagno, G Tedeschi, S Nonnis, ...
Journal of molecular biology 385 (1), 140-152, 2009
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
F Cossu, E Mastrangelo, M Milani, G Sorrentino, D Lecis, D Delia, ...
Biochemical and biophysical research communications 378 (2), 162-167, 2009
Flaviviral methyltransferase/RNA interaction: structural basis for enzyme inhibition
M Milani, E Mastrangelo, M Bollati, B Selisko, E Decroly, M Bouvet, ...
Antiviral research 83 (1), 28-34, 2009
Targeting the BIR domains of inhibitor of apoptosis (IAP) proteins in cancer treatment
F Cossu, M Milani, E Mastrangelo, D Lecis
Computational and Structural Biotechnology Journal 17, 142-150, 2019
Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds
R Croci, M Pezzullo, D Tarantino, M Milani, SC Tsay, R Sureshbabu, ...
PloS one 9 (3), e91765, 2014
Structural basis for bivalent Smac-mimetics recognition in the IAP protein family
F Cossu, M Milani, E Mastrangelo, P Vachette, F Servida, D Lecis, ...
Journal of molecular biology 392 (3), 630-644, 2009
Ferredoxin-NADP+ reductase from Plasmodium falciparum undergoes NADP+-dependent dimerization and inactivation: functional and crystallographic analysis
M Milani, E Balconi, A Aliverti, E Mastrangelo, F Seeber, M Bolognesi, ...
Journal of molecular biology 367 (2), 501-513, 2007
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor
D Tarantino, R Cannalire, E Mastrangelo, R Croci, G Querat, ML Barreca, ...
Antiviral research 134, 226-235, 2016
Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase
D Tarantino, M Pezzullo, E Mastrangelo, R Croci, J Rohayem, I Robel, ...
Antiviral research 102, 23-28, 2014
Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo [5.3. 0] alkane smac mimetics. Structure, activity, and recognition principles
E Mastrangelo, F Cossu, M Milani, G Sorrentino, D Lecis, D Delia, ...
Journal of molecular biology 384 (3), 673-689, 2008
Liposomal systems as nanocarriers for the antiviral agent ivermectin
R Croci, E Bottaro, KWK Chan, S Watanabe, M Pezzullo, E Mastrangelo, ...
International journal of biomaterials 2016, 2016
Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy
P Seneci, A Bianchi, C Battaglia, L Belvisi, M Bolognesi, A Caprini, ...
Bioorganic & medicinal chemistry 17 (16), 5834-5856, 2009
Role and inhibition of GLI1 protein in cancer
E Mastrangelo, M Milani
Lung Cancer: Targets and Therapy, 35-43, 2018
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