| Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug E Mastrangelo, M Pezzullo, T De Burghgraeve, S Kaptein, B Pastorino, ... Journal of Antimicrobial Chemotherapy 67 (8), 1884-1894, 2012 | 457 | 2012 |
| Structure and functionality in flavivirus NS-proteins: perspectives for drug design M Bollati, K Alvarez, R Assenberg, C Baronti, B Canard, S Cook, ... Antiviral research 87 (2), 125-148, 2010 | 435 | 2010 |
| Crystal structure of a novel conformational state of the flavivirus NS3 protein: implications for polyprotein processing and viral replication R Assenberg, E Mastrangelo, TS Walter, A Verma, M Milani, RJ Owens, ... Journal of virology 83 (24), 12895-12906, 2009 | 177 | 2009 |
| Ebolavirus and Marburgvirus: insight the Filoviridae family P Ascenzi, A Bocedi, J Heptonstall, MR Capobianchi, A Di Caro, ... Molecular aspects of medicine 29 (3), 151-185, 2008 | 144 | 2008 |
| Structure-based inhibition of Norovirus RNA-dependent RNA polymerases E Mastrangelo, M Pezzullo, D Tarantino, R Petazzi, F Germani, D Kramer, ... Journal of molecular biology 419 (3-4), 198-210, 2012 | 109 | 2012 |
| Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib D Lecis, C Drago, L Manzoni, P Seneci, C Scolastico, E Mastrangelo, ... British journal of cancer 102 (12), 1707-1716, 2010 | 103 | 2010 |
| Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein E Mastrangelo, M Milani, M Bollati, B Selisko, F Peyrane, V Pandini, ... Journal of molecular biology 372 (2), 444-455, 2007 | 99 | 2007 |
| Recognition of RNA cap in the Wesselsbron virus NS5 methyltransferase domain: implications for RNA-capping mechanisms in Flavivirus M Bollati, M Milani, E Mastrangelo, S Ricagno, G Tedeschi, S Nonnis, ... Journal of molecular biology 385 (1), 140-152, 2009 | 94 | 2009 |
| Targeting the BIR domains of inhibitor of apoptosis (IAP) proteins in cancer treatment F Cossu, M Milani, E Mastrangelo, D Lecis Computational and Structural Biotechnology Journal 17, 142-150, 2019 | 84 | 2019 |
| Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2 F Cossu, E Mastrangelo, M Milani, G Sorrentino, D Lecis, D Delia, ... Biochemical and biophysical research communications 378 (2), 162-167, 2009 | 72 | 2009 |
| Flaviviral methyltransferase/RNA interaction: structural basis for enzyme inhibition M Milani, E Mastrangelo, M Bollati, B Selisko, E Decroly, M Bouvet, ... Antiviral research 83 (1), 28-34, 2009 | 70 | 2009 |
| Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds R Croci, M Pezzullo, D Tarantino, M Milani, SC Tsay, R Sureshbabu, ... PloS one 9 (3), e91765, 2014 | 62 | 2014 |
| Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase D Tarantino, M Pezzullo, E Mastrangelo, R Croci, J Rohayem, I Robel, ... Antiviral research 102, 23-28, 2014 | 57 | 2014 |
| Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor D Tarantino, R Cannalire, E Mastrangelo, R Croci, G Querat, ML Barreca, ... Antiviral research 134, 226-235, 2016 | 56 | 2016 |
| Liposomal systems as nanocarriers for the antiviral agent ivermectin R Croci, E Bottaro, KWK Chan, S Watanabe, M Pezzullo, E Mastrangelo, ... International journal of biomaterials 2016, 2016 | 53 | 2016 |
| Structural basis for bivalent Smac-mimetics recognition in the IAP protein family F Cossu, M Milani, E Mastrangelo, P Vachette, F Servida, D Lecis, ... Journal of molecular biology 392 (3), 630-644, 2009 | 52 | 2009 |
| Ferredoxin-NADP+ reductase from Plasmodium falciparum undergoes NADP+-dependent dimerization and inactivation: functional and crystallographic analysis M Milani, E Balconi, A Aliverti, E Mastrangelo, F Seeber, M Bolognesi, ... Journal of molecular biology 367 (2), 501-513, 2007 | 51 | 2007 |
| Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy P Seneci, A Bianchi, C Battaglia, L Belvisi, M Bolognesi, A Caprini, ... Bioorganic & medicinal chemistry 17 (16), 5834-5856, 2009 | 50 | 2009 |
| Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo [5.3. 0] alkane smac mimetics. Structure, activity, and recognition principles E Mastrangelo, F Cossu, M Milani, G Sorrentino, D Lecis, D Delia, ... Journal of molecular biology 384 (3), 673-689, 2008 | 49 | 2008 |
| Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis L Muzio, R Sirtori, D Gornati, S Eleuteri, A Fossaghi, D Brancaccio, ... Nature communications 11 (1), 3848, 2020 | 43 | 2020 |
