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Kaleeckal G. Harikumar, Mphil, PhD
Kaleeckal G. Harikumar, Mphil, PhD
Mayo clinic: Assistant Professor in Medicine
Email verificata su mayo.edu
Titolo
Citata da
Citata da
Anno
Dependence of critical micelle concentration of a zwitterionic detergent on ionic strength: implications in receptor solubilization
A Chattopadhyay, KG Harikumar
FEBS letters 391 (1-2), 199-202, 1996
1591996
Structure and function of Norrin in assembly and activation of a Frizzled 4–Lrp5/6 complex
J Ke, KG Harikumar, C Erice, C Chen, X Gu, L Wang, N Parker, Z Cheng, ...
Genes & development 27 (21), 2305-2319, 2013
1302013
Single-molecule FRET imaging of GPCR dimers in living cells
WB Asher, P Geggier, MD Holsey, GT Gilmore, AK Pati, J Meszaros, ...
Nature methods 18 (4), 397-405, 2021
1182021
Transmembrane segment IV contributes a functionally important interface for oligomerization of the Class II G protein-coupled secretin receptor
KG Harikumar, DI Pinon, LJ Miller
Journal of biological chemistry 282 (42), 30363-30372, 2007
1172007
Crystal structure of the Frizzled 4 receptor in a ligand-free state
S Yang, Y Wu, TH Xu, PW de Waal, Y He, M Pu, Y Chen, ZJ DeBruine, ...
Nature 560 (7720), 666-670, 2018
1012018
Differential effects of modification of membrane cholesterol and sphingolipids on the conformation, function, and trafficking of the G protein-coupled cholecystokinin receptor
KG Harikumar, V Puri, RD Singh, K Hanada, RE Pagano, LJ Miller
Journal of Biological Chemistry 280 (3), 2176-2185, 2005
932005
Heterodimerization of type A and B cholecystokinin receptors enhance signaling and promote cell growth
ZJ Cheng, KG Harikumar, EL Holicky, LJ Miller
Journal of Biological Chemistry 278 (52), 52972-52979, 2003
862003
Constitutive formation of oligomeric complexes between family BG protein-coupled vasoactive intestinal polypeptide and secretin receptors
KG Harikumar, MM Morfis, CS Lisenbee, PM Sexton, LJ Miller
Molecular pharmacology 69 (1), 363-373, 2006
852006
G-protein-dependent cell surface dynamics of the human serotonin1A receptor tagged to yellow fluorescent protein
TJ Pucadyil, S Kalipatnapu, KG Harikumar, N Rangaraj, SS Karnik, ...
Biochemistry 43 (50), 15852-15862, 2004
832004
Dimeric arrangement of the parathyroid hormone receptor and a structural mechanism for ligand-induced dissociation
AA Pioszak, KG Harikumar, NR Parker, LJ Miller, HE Xu
Journal of biological chemistry 285 (16), 12435-12444, 2010
762010
Induced Association of μ Opioid (MOP) and Type 2 Cholecystokinin (CCK2) Receptors by Novel Bivalent Ligands
Y Zheng, E Akgün, KG Harikumar, J Hopson, MD Powers, MM Lunzer, ...
Journal of medicinal chemistry 52 (2), 247-258, 2009
762009
Glucagon-like peptide-1 receptor dimerization differentially regulates agonist signaling but does not affect small molecule allostery
KG Harikumar, D Wootten, DI Pinon, C Koole, AM Ball, SGB Furness, ...
Proceedings of the National Academy of Sciences 109 (45), 18607-18612, 2012
702012
Molecular basis of association of receptor activity-modifying protein 3 with the family BG protein-coupled secretin receptor
KG Harikumar, J Simms, G Christopoulos, PM Sexton, LJ Miller
Biochemistry 48 (49), 11773-11785, 2009
662009
Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization
ZJ DeBruine, J Ke, KG Harikumar, X Gu, P Borowsky, BO Williams, W Xu, ...
Genes & development 31 (9), 916-926, 2017
632017
Pattern of intra-family hetero-oligomerization involving the G-protein-coupled secretin receptor
KG Harikumar, MM Morfis, PM Sexton, LJ Miller
Journal of molecular neuroscience 36, 279-285, 2008
602008
Role of cholesterol in ligand binding and G-protein coupling of serotonin1A receptors solubilized from bovine hippocampus
A Chattopadhyay, M Jafurulla, S Kalipatnapu, TJ Pucadyil, KG Harikumar
Biochemical and Biophysical Research Communications 327 (4), 1036-1041, 2005
602005
Differential sensitivity of types 1 and 2 cholecystokinin receptors to membrane cholesterol
RM Potter, KG Harikumar, SV Wu, LJ Miller
Journal of lipid research 53 (1), 137-148, 2012
572012
Environment and mobility of a series of fluorescent reporters at the amino terminus of structurally related peptide agonists and antagonists bound to the cholecystokinin receptor
KG Harikumar, DI Pinon, WS Wessels, FG Prendergast, LJ Miller
Journal of Biological Chemistry 277 (21), 18552-18560, 2002
572002
Dimerization in the absence of higher-order oligomerization of the G protein-coupled secretin receptor
KG Harikumar, RM Happs, LJ Miller
Biochimica et Biophysica Acta (BBA)-Biomembranes 1778 (11), 2555-2563, 2008
542008
Functional importance of a structurally distinct homodimeric complex of the family BG protein-coupled secretin receptor
F Gao, KG Harikumar, M Dong, PCH Lam, PM Sexton, A Christopoulos, ...
Molecular pharmacology 76 (2), 264-274, 2009
512009
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