CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand D Depoil, S Fleire, BL Treanor, M Weber, NE Harwood, KL Marchbank, ... Nature immunology 9 (1), 63-72, 2008 | 436 | 2008 |
Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical … I Moore, L Strain, I Pappworth, D Kavanagh, PN Barlow, AP Herbert, ... Blood, The Journal of the American Society of Hematology 115 (2), 379-387, 2010 | 401 | 2010 |
Complement: central to innate immunity and bridging to adaptive responses BP Morgan, KJ Marchbank, MP Longhi, CL Harris, AM Gallimore Immunology letters 97 (2), 171-179, 2005 | 260 | 2005 |
Determining the population frequency of the CFHR3/CFHR1 deletion at 1q32 LV Holmes, L Strain, SJ Staniforth, I Moore, K Marchbank, D Kavanagh, ... PloS one 8 (4), e60352, 2013 | 134 | 2013 |
A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome NJ Francis, B McNicholas, A Awan, M Waldron, D Reddan, D Sadlier, ... Blood, The Journal of the American Society of Hematology 119 (2), 591-601, 2012 | 107 | 2012 |
Factor H autoantibodies in membranoproliferative glomerulonephritis THJ Goodship, IY Pappworth, T Toth, M Denton, K Houlberg, ... Molecular immunology 52 (3-4), 200-206, 2012 | 105 | 2012 |
Molecular cloning, chromosomal localization, expression, and functional characterization of the mouse analogue of human CD59. MB Powell, KJ Marchbank, NK Rushmere, CW Van den Berg, BP Morgan Journal of immunology (Baltimore, Md.: 1950) 158 (4), 1692-1702, 1997 | 96 | 1997 |
Characterization of the mouse analogues of CD59 using novel monoclonal antibodies: tissue distribution and functional comparison CL Harris, SM Hanna, M Mizuno, DS Holt, KJ Marchbank, BP Morgan Immunology 109 (1), 117-126, 2003 | 82 | 2003 |
An extended mini-complement factor H molecule ameliorates experimental C3 glomerulopathy EM Nichols, TD Barbour, IY Pappworth, EKS Wong, JM Palmer, ... Kidney international 88 (6), 1314-1322, 2015 | 76 | 2015 |
Factor I autoantibodies in patients with atypical hemolytic uremic syndrome: disease-associated or an epiphenomenon? D Kavanagh, IY Pappworth, H Anderson, CM Hayes, I Moore, EM Hunze, ... Clinical Journal of the American Society of Nephrology 7 (3), 417-426, 2012 | 73 | 2012 |
Factor H autoantibody is associated with atypical hemolytic uremic syndrome in children in the United Kingdom and Ireland V Brocklebank, S Johnson, TP Sheerin, SD Marks, RD Gilbert, K Tyerman, ... Kidney international 92 (5), 1261-1271, 2017 | 68 | 2017 |
Standardisation of the factor H autoantibody assay R Watson, S Lindner, P Bordereau, EM Hunze, F Tak, S Ngo, PF Zipfel, ... Immunobiology 219 (1), 9-16, 2014 | 58 | 2014 |
Thermal stability, storage and release of proteins with tailored fit in silica YC Chen, T Smith, RH Hicks, A Doekhie, F Koumanov, SA Wells, KJ Edler, ... Scientific reports 7 (1), 46568, 2017 | 57 | 2017 |
The role of ADAMTS‐13 activity and complement mutational analysis in differentiating acute thrombotic microangiopathies EH Phillips, JP Westwood, V Brocklebank, EKS Wong, JO Tellez, ... Journal of Thrombosis and Haemostasis 14 (1), 175-185, 2016 | 56 | 2016 |
Characterization of a factor H mutation that perturbs the alternative pathway of complement in a family with membranoproliferative GN EKS Wong, HE Anderson, AP Herbert, RC Challis, P Brown, GS Reis, ... Journal of the American Society of Nephrology 25 (11), 2425-2433, 2014 | 53 | 2014 |
Thrombotic microangiopathy in inverted formin 2–mediated renal disease RC Challis, T Ring, Y Xu, EKS Wong, O Flossmann, ISD Roberts, ... Journal of the American Society of Nephrology 28 (4), 1084-1091, 2017 | 52 | 2017 |
Loxosceles spider venom induces metalloproteinase mediated cleavage of MCP/CD46 and MHCI and induces protection against C‐mediated lysis CW Van Den Berg, RMG De Andrade, FC Magnoli, KJ Marchbank, ... Immunology 107 (1), 102-110, 2002 | 52 | 2002 |
A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H–Related 3 Gene in Atypical Hemolytic Uremic … RC Challis, GSR Araujo, EKS Wong, HE Anderson, A Awan, AM Dorman, ... Journal of the American Society of Nephrology 27 (6), 1617-1624, 2016 | 50 | 2016 |
Triggering of atypical hemolytic uremic syndrome by influenza A (H1N1) D Bento, J Mapril, C Rocha, KJ Marchbank, D Kavanagh, D Barge, ... Renal failure 32 (6), 753-756, 2010 | 45 | 2010 |
Successful renal transplantation in factor H autoantibody associated HUS with CFHR1 and 3 deficiency and CFH variant G2850T AM Waters, I Pappworth, K Marchbank, D Bockenhauer, K Tullus, ... American Journal of Transplantation 10 (1), 168-172, 2010 | 45 | 2010 |