| Circulating microRNAs as novel biomarkers for platelet activation P Willeit, A Zampetaki, K Dudek, D Kaudewitz, A King, NS Kirkby, ... Circulation research 112 (4), 595-600, 2013 | 438 | 2013 |
| The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house? NS Kirkby, PWF Hadoke, AJ Bagnall, DJ Webb British journal of pharmacology 153 (6), 1105-1119, 2008 | 223 | 2008 |
| Eicosanoids, prostacyclin and cyclooxygenase in the cardiovascular system JA Mitchell, NS Kirkby British journal of pharmacology 176 (8), 1038-1050, 2019 | 195 | 2019 |
| In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation PCJ Armstrong, PD Leadbeater, MV Chan, NS Kirkby, JA Jakubowski, ... Journal of Thrombosis and Haemostasis 9 (3), 552-561, 2011 | 191 | 2011 |
| Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways NS Kirkby, MV Chan, AK Zaiss, E Garcia-Vaz, J Jiao, LM Berglund, ... Proceedings of the National Academy of Sciences 113 (2), 434-439, 2016 | 184 | 2016 |
| Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system NS Kirkby, MH Lundberg, LS Harrington, PDM Leadbeater, GL Milne, ... Proceedings of the National Academy of Sciences 109 (43), 17597-17602, 2012 | 153 | 2012 |
| Evidence for the involvement of type I interferon in pulmonary arterial hypertension PM George, E Oliver, P Dorfmuller, OD Dubois, DM Reed, NS Kirkby, ... Circulation research 114 (4), 677-688, 2014 | 142 | 2014 |
| Role of prostacyclin in pulmonary hypertension JA Mitchell, B Ahmetaj-Shala, NS Kirkby, WR Wright, LS Mackenzie, ... Global Cardiology Science and Practice 2014 (4), 53, 2015 | 101 | 2015 |
| Evidence that links loss of cyclooxygenase-2 with increased asymmetric dimethylarginine: novel explanation of cardiovascular side effects associated with anti-inflammatory drugs B Ahmetaj-Shala, NS Kirkby, R Knowles, M Al’Yamani, S Mazi, Z Wang, ... Circulation 131 (7), 633-642, 2015 | 98 | 2015 |
| Antiplatelet effects of aspirin vary with level of P2Y12 receptor blockade supplied by either ticagrelor or prasugrel NS Kirkby, PDM Leadbeater, MV Chan, S Nylander, JA Mitchell, ... Journal of Thrombosis and Haemostasis 9 (10), 2103-2105, 2011 | 79 | 2011 |
| Cryptogenic multifocal ulcerating stenosing enteritis associated with homozygous deletion mutations in cytosolic phospholipase A2-α MA Brooke, HJ Longhurst, V Plagnol, NS Kirkby, JA Mitchell, ... Gut 63 (1), 96-104, 2014 | 78 | 2014 |
| Characterization of multiple platelet activation pathways in patients with bleeding as a high-throughput screening option: use of 96-well Optimul assay M Lordkipanidzé, GC Lowe, NS Kirkby, MV Chan, MH Lundberg, ... Blood, The Journal of the American Society of Hematology 123 (8), e11-e22, 2014 | 74 | 2014 |
| LC-MS/MS confirms that COX-1 drives vascular prostacyclin whilst gene expression pattern reveals non-vascular sites of COX-2 expression NS Kirkby, AK Zaiss, P Urquhart, J Jiao, PJ Austin, M Al-Yamani, ... PloS one 8 (7), e69524, 2013 | 71 | 2013 |
| Blockade of the purinergic P2Y12 receptor greatly increases the platelet inhibitory actions of nitric oxide NS Kirkby, MH Lundberg, MV Chan, I Vojnovic, AB Solomon, M Emerson, ... Proceedings of the National Academy of Sciences 110 (39), 15782-15787, 2013 | 70 | 2013 |
| Optical multichannel (optimul) platelet aggregometry in 96-well plates as an additional method of platelet reactivity testing MV Chan, PCJ Armstrong, F Papalia, NS Kirkby, TD Warner Platelets 22 (7), 485-494, 2011 | 69 | 2011 |
| Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia R d’Emmanuele di Villa Bianca, E Mitidieri, MND Di Minno, NS Kirkby, ... Proceedings of the National Academy of Sciences 110 (39), 15812-15817, 2013 | 63 | 2013 |
| Aspirin inhibits the production of proangiogenic 15 (S)-HETE by platelet cyclooxygenase-1 F Rauzi, NS Kirkby, ML Edin, J Whiteford, DC Zeldin, JA Mitchell, ... The FASEB Journal 30 (12), 4256, 2016 | 62 | 2016 |
| COX-2 protects against atherosclerosis independently of local vascular prostacyclin: identification of COX-2 associated pathways implicate Rgl1 and lymphocyte networks NS Kirkby, MH Lundberg, WR Wright, TD Warner, MJ Paul-Clark, ... PLoS One 9 (6), e98165, 2014 | 60 | 2014 |
| Differential role of pannexin-1/ATP/P2X7 axis in IL-1β release by human monocytes K Parzych, AV Zetterqvist, WR Wright, NS Kirkby, JA Mitchell, ... The FASEB Journal 31 (6), 2439, 2017 | 55 | 2017 |
| Differential COX-2 induction by viral and bacterial PAMPs: Consequences for cytokine and interferon responses and implications for anti-viral COX-2 directed therapies NS Kirkby, AK Zaiss, WR Wright, J Jiao, MV Chan, TD Warner, ... Biochemical and biophysical research communications 438 (2), 249-256, 2013 | 52 | 2013 |
