Engin Ízkan
Engin Ízkan
Assistant Professor, University of Chicago
Verified email at uchicago.edu
Cited by
Cited by
Gabapentin receptor α2δ-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis
C Eroglu, NJ Allen, MW Susman, NA O'Rourke, CY Park, E Ízkan, ...
Cell 139 (2), 380-392, 2009
Deconstructing the peptide-MHC specificity of T cell recognition
ME Birnbaum, JL Mendoza, DK Sethi, S Dong, J Glanville, J Dobbins, ...
Cell 157 (5), 1073-1087, 2014
Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies
K Weiskopf, AM Ring, CCM Ho, JP Volkmer, AM Levin, AK Volkmer, ...
Science 341 (6141), 88-91, 2013
Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases
E Ízkan, H Yu, J Deisenhofer
Proceedings of the National Academy of Sciences 102 (52), 18890-18895, 2005
APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex
Z Tang, B Li, R Bharadwaj, H Zhu, E Ízkan, K Hakala, J Deisenhofer, ...
Molecular biology of the cell 12 (12), 3839-3851, 2001
Structures of neuroligin-1 and the neuroligin-1/neurexin-1β complex reveal specific protein-protein and protein-Ca2+ interactions
D Araš, AA Boucard, E Ízkan, P Strop, E Newell, TC SŘdhof, AT Brunger
Neuron 56 (6), 992-1003, 2007
Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15
AM Ring, JX Lin, D Feng, S Mitra, M Rickert, GR Bowman, VS Pande, P Li, ...
Nature immunology 13 (12), 1187-1195, 2012
An extracellular interactome of immunoglobulin and LRR proteins reveals receptor-ligand networks
E Ízkan, RA Carrillo, CL Eastman, R Weiszmann, D Waghray, ...
Cell 154 (1), 228-239, 2013
Molecular and structural insight into proNGF engagement of p75NTR and sortilin
D Feng, T Kim, E Ízkan, M Light, R Torkin, KK Teng, BL Hempstead, ...
Journal of molecular biology 396 (4), 967-984, 2010
Control of synaptic connectivity by a network of Drosophila IgSF cell surface proteins
RA Carrillo, E Ízkan, KP Menon, S Nagarkar-Jaiswal, PT Lee, M Jeon, ...
Cell 163 (7), 1770-1782, 2015
The plug domain of FepA, a TonB-dependent transport protein from Escherichia coli, binds its siderophore in the absence of the transmembrane barrel domain
KC Usher, E Ízkan, KH Gardner, J Deisenhofer
Proceedings of the National Academy of Sciences 98 (19), 10676-10681, 2001
“Velcro” engineering of high affinity CD47 ectodomain as signal regulatory protein α (SIRPα) antagonists that enhance antibody-dependent cellular phagocytosis
CCM Ho, N Guo, JT Sockolosky, AM Ring, K Weiskopf, E Ízkan, Y Mori, ...
Journal of Biological Chemistry 290 (20), 12650-12663, 2015
MADD-4/punctin and neurexin organize C. elegans GABAergic postsynapses through neuroligin
GS Maro, S Gao, AM Olechwier, WL Hung, M Liu, E Ízkan, M Zhen, ...
Neuron 86 (6), 1420-1432, 2015
Extracellular architecture of the SYG-1/SYG-2 adhesion complex instructs synaptogenesis
E Ízkan, PH Chia, RR Wang, N Goriatcheva, D Borek, Z Otwinowski, ...
Cell 156 (3), 482-494, 2014
Plum, an immunoglobulin superfamily protein, regulates axon pruning by facilitating TGF-β signaling.
XM Yu, I Gutman, TJ Mosca, T Iram, E Ozkan, KC Garcia, L Luo, ...
Neuron 78 (3), 456-468, 2013
Structure of an intermediate conformer of the spindle checkpoint protein Mad2
M Hara, E Ízkan, H Sun, H Yu, X Luo
Proceedings of the National Academy of Sciences 112 (36), 11252-11257, 2015
Neural immunoglobulin superfamily interaction networks
K Zinn, E Ízkan
Current opinion in neurobiology 45, 99-105, 2017
Conformational plasticity in the transsynaptic neurexin-cerebellin-glutamate receptor adhesion complex
S Cheng, AB Seven, J Wang, G Skiniotis, E Ízkan
Structure 24 (12), 2163-2173, 2016
Precise regulation of the guidance receptor DMA-1 by KPC-1/Furin instructs dendritic branching decisions
X Dong, H Chiu, YJ Park, W Zou, Y Zou, E Ízkan, C Chang, K Shen
Elife 5, e11008, 2016
Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila
S Cheng, J Ashley, JD Kurleto, M Lobb-Rabe, YJ Park, RA Carrillo, ...
Elife 8, e41028, 2019
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