| MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling JA Engelman, K Zejnullahu, T Mitsudomi, Y Song, C Hyland, JO Park, ... science 316 (5827), 1039-1043, 2007 | 5172 | 2007 |
| First-line crizotinib versus chemotherapy in ALK-positive lung cancer BJ Solomon, T Mok, DW Kim, YL Wu, K Nakagawa, T Mekhail, E Felip, ... N Engl j Med 371, 2167-2177, 2014 | 3195 | 2014 |
| Atezolizumab for first-line treatment of metastatic nonsquamous NSCLC MA Socinski, RM Jotte, F Cappuzzo, F Orlandi, D Stroyakovskiy, ... New England Journal of Medicine 378 (24), 2288-2301, 2018 | 2723 | 2018 |
| Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective … W De Roock, B Claes, D Bernasconi, J De Schutter, B Biesmans, ... The lancet oncology 11 (8), 753-762, 2010 | 2443 | 2010 |
| First-line nivolumab in stage IV or recurrent non–small-cell lung cancer DP Carbone, M Reck, L Paz-Ares, B Creelan, L Horn, M Steins, E Felip, ... New England Journal of Medicine 376 (25), 2415-2426, 2017 | 2190 | 2017 |
| Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non–small-cell lung cancer F Cappuzzo, FR Hirsch, E Rossi, S Bartolini, GL Ceresoli, L Bemis, ... Journal of the National Cancer Institute 97 (9), 643-655, 2005 | 1939 | 2005 |
| Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study F Cappuzzo, T Ciuleanu, L Stelmakh, S Cicenas, A Szczésna, E Juhász, ... The lancet oncology 11 (6), 521-529, 2010 | 1543 | 2010 |
| Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase … NA Rizvi, J Mazières, D Planchard, TE Stinchcombe, GK Dy, SJ Antonia, ... The lancet oncology 16 (3), 257-265, 2015 | 1509 | 2015 |
| Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer M Peifer, L Fernández-Cuesta, ML Sos, J George, D Seidel, LH Kasper, ... Nature genetics 44 (10), 1104-1110, 2012 | 1318 | 2012 |
| Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy … EB Garon, TE Ciuleanu, O Arrieta, K Prabhash, KN Syrigos, T Goksel, ... The Lancet 384 (9944), 665-673, 2014 | 1218 | 2014 |
| Atezolizumab in combination with carboplatin plus nab-paclitaxel chemotherapy compared with chemotherapy alone as first-line treatment for metastatic non-squamous non-small … H West, M McCleod, M Hussein, A Morabito, A Rittmeyer, HJ Conter, ... The Lancet Oncology 20 (7), 924-937, 2019 | 999 | 2019 |
| Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer J Weiss, ML Sos, D Seidel, M Peifer, T Zander, JM Heuckmann, RT Ullrich, ... Science translational medicine 2 (62), 62ra93-62ra93, 2010 | 949 | 2010 |
| Atezolizumab plus bevacizumab and chemotherapy in non-small-cell lung cancer (IMpower150): key subgroup analyses of patients with EGFR mutations or baseline liver metastases in … M Reck, TSK Mok, M Nishio, RM Jotte, F Cappuzzo, F Orlandi, ... The Lancet Respiratory Medicine 7 (5), 387-401, 2019 | 677 | 2019 |
| Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab K Yonesaka, K Zejnullahu, I Okamoto, T Satoh, F Cappuzzo, J Souglakos, ... Science translational medicine 3 (99), 99ra86-99ra86, 2011 | 636 | 2011 |
| Increased MET gene copy number negatively affects survival of surgically resected non–small-cell lung cancer patients F Cappuzzo, A Marchetti, M Skokan, E Rossi, S Gajapathy, L Felicioni, ... Journal of clinical oncology 27 (10), 1667, 2009 | 597 | 2009 |
| PD-1 and PD-L1 expression in molecularly selected non-small-cell lung cancer patients A D'incecco, M Andreozzi, V Ludovini, E Rossi, A Capodanno, L Landi, ... British journal of cancer 112 (1), 95-102, 2015 | 587 | 2015 |
| Identifying and Targeting ROS1 Gene Fusions in Non–Small Cell Lung CancerROS1 Gene Fusions in NSCLC KD Davies, AT Le, MF Theodoro, MC Skokan, DL Aisner, EM Berge, ... Clinical Cancer Research 18 (17), 4570-4579, 2012 | 483 | 2012 |
| Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor–positive non–small-cell lung cancer patients F Cappuzzo, M Varella-Garcia, H Shigematsu, I Domenichini, S Bartolini, ... Journal of clinical oncology 23 (22), 5007-5018, 2005 | 458 | 2005 |
| Akt phosphorylation and gefitinib efficacy in patients with advanced non–small-cell lung cancer F Cappuzzo, E Magrini, GL Ceresoli, S Bartolini, E Rossi, V Ludovini, ... Journal of the National Cancer Institute 96 (15), 1133-1141, 2004 | 453 | 2004 |
| Gefitinib in patients with brain metastases from non-small-cell lung cancer: a prospective trial GL Ceresoli, F Cappuzzo, V Gregorc, S Bartolini, L Crino, E Villa Annals of Oncology 15 (7), 1042-1047, 2004 | 412 | 2004 |
Romano DanesiProfessor of Pharmacology, University of PisaEmail verificata su unipi.it
