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Mohamed Kreir
Mohamed Kreir
Janssen Pharmaceutical Companies of Johnson & Johnson
Verified email at its.jnj.com - Homepage
Title
Cited by
Cited by
Year
Human TRPA1 is intrinsically cold-and chemosensitive with and without its N-terminal ankyrin repeat domain
L Moparthi, S Survery, M Kreir, C Simonsen, P Kjellbom, ED Högestätt, ...
Proceedings of the National Academy of Sciences 111 (47), 16901-16906, 2014
1652014
Rapid screening of membrane protein activity: electrophysiological analysis of OmpF reconstituted in proteoliposomes
M Kreir, C Farre, M Beckler, M George, N Fertig
Lab on a Chip 8 (4), 587-595, 2008
1282008
Permeation of Antibiotics through Escherichia coli OmpF and OmpC Porins: Screening for Influx on a Single-Molecule Level
KR Mahendran, M Kreir, H Weingart, N Fertig, M Winterhalter
Journal of biomolecular Screening 15 (3), 302-307, 2010
1212010
Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins
D Shaya, M Kreir, RA Robbins, S Wong, J Hammon, A Brüggemann, ...
Proceedings of the National Academy of Sciences 108 (30), 12313-12318, 2011
982011
Port-a-patch and patchliner: high fidelity electrophysiology for secondary screening and safety pharmacology
C Farre, A Haythornthwaite, C Haarmann, S Stoelzle, M Kreir, M George, ...
Combinatorial chemistry & high throughput screening 12 (1), 24-37, 2009
802009
The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics
E Sancho-Vaello, D Gil-Carton, P François, EJ Bonetti, M Kreir, ...
Scientific reports 10 (1), 17356, 2020
692020
Natural and artificial ion channels for biosensing platforms
L Steller, M Kreir, R Salzer
Analytical and bioanalytical chemistry 402, 209-230, 2012
632012
Generation of a human induced pluripotent stem cell–based model for tauopathies combining three microtubule‐associated protein TAU mutations which displays several phenotypes …
JA García‐León, A Cabrera‐Socorro, K Eggermont, A Swijsen, J Terryn, ...
Alzheimer's & Dementia 14 (10), 1261-1280, 2018
522018
Do in vitro assays in rat primary neurons predict drug-induced seizure liability in humans?
M Kreir, B Van Deuren, S Versweyveld, A De Bondt, I Van den Wyngaert, ...
Toxicology and Applied Pharmacology 346, 45-57, 2018
482018
Membrane assembly of the functional KcsA potassium channel in a vesicle-based eukaryotic cell-free translation system
SK Dondapati, M Kreir, RB Quast, DA Wüstenhagen, A Brüggemann, ...
Biosensors and Bioelectronics 59, 174-183, 2014
482014
Planar patch clamp: advances in electrophysiology
A Brüggemann, C Farre, C Haarmann, A Haythornthwaite, M Kreir, ...
Potassium Channels: Methods and Protocols, 165-176, 2009
482009
Design, synthesis and functional analysis of dansylated polytheonamide mimic: an artificial peptide ion channel
H Itoh, S Matsuoka, M Kreir, M Inoue
Journal of the American Chemical Society 134 (34), 14011-14018, 2012
332012
The M34A mutant of Connexin26 reveals active conductance states in pore-suspending membranes
O Gaßmann, M Kreir, C Ambrosi, J Pranskevich, A Oshima, C Röling, ...
Journal of structural biology 168 (1), 168-176, 2009
332009
SOX9-induced generation of functional astrocytes supporting neuronal maturation in an all-human system
K Neyrinck, J Van Den Daele, T Vervliet, J De Smedt, K Wierda, M Nijs, ...
Stem Cell Reviews and Reports 17 (5), 1855-1873, 2021
232021
Antibiotic translocation through porins studied in planar lipid bilayers using parallel platforms
C Weichbrodt, H Bajaj, G Baaken, J Wang, S Guinot, M Kreir, ...
Analyst 140 (14), 4874-4881, 2015
222015
Green fluorescent protein changes the conductance of connexin 43 (Cx43) hemichannels reconstituted in planar lipid bilayers
C Carnarius, M Kreir, M Krick, C Methfessel, V Moehrle, O Valerius, ...
Journal of Biological Chemistry 287 (4), 2877-2886, 2012
222012
Role of Kv7. 2/Kv7. 3 and M1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons
M Kreir, A De Bondt, I Van den Wyngaert, G Teuns, HR Lu, DJ Gallacher
European Journal of Pharmacology 858, 172474, 2019
152019
Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies
PY Shih, M Kreir, D Kumar, F Seibt, F Pestana, B Schmid, B Holst, ...
Stem Cell Research 54, 102386, 2021
122021
Functional characterization of p7 viroporin from hepatitis C virus produced in a cell-free expression system
T Soranzo, S Cortès, F Gilde, M Kreir, C Picart, JL Lenormand
Protein expression and purification 118, 83-91, 2016
112016
Cell-free expression of a functional pore-only sodium channel
G Kovácsová, E Gustavsson, J Wang, M Kreir, S Peuker, S Westenhoff
Protein Expression and Purification 111, 42-47, 2015
102015
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